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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:

23卷

期数:

2017年04期

页码:

354-356

栏目:

临床医学

出版日期:

2017-07-02

文章信息/Info

Title:

Impact of diabetes mellitus on postoperative complications after pancreaticoduodenectomy

文章编号:

1006-8147(2017)04-0354-03

作者:

王开毫; 田伟军

（天津医科大学总医院普通外科，天津 300052）

Author(s):

WANG Kai-hao;  TIAN Wei-jun

（Department of General Surgery, General Hospital，Tianjin Medical University, Tianjin 300052, China）

关键词:

糖尿病; 胰十二指肠切除术; 术后并发症; 胰瘘; 术后血糖

Keywords:

diabetes mellitus; pancreaticoduodenectomy; postoperative complications; pancreatic fistula; postoperative blood glucose

分类号:

R656

DOI:

-

文献标志码:

A

摘要:

目的：探讨糖尿病对胰十二指肠切除术（PD）患者术后并发症的影响。方法：回顾性分析110例行胰十二指肠切除术患者的临床资料。根据术前是否合并糖尿病分为糖尿病组（32例）和非糖尿病组（78例），比较两组患者术后胰瘘等并发症发生情况。结果：糖尿病组和非糖尿病组患者术后胰瘘发生率分别为59.4%和38.5%，差异有统计学意义（P ＜0.05）。两组患者术后胃排空延迟、术后感染、胆漏、术后出血发生率以及住院时间和住院花费的差异均无统计学意义（P ＞0.05）。胰瘘患者中合并糖尿病（χ²=4.018，P ＜0.05）和术后血糖控制不佳（χ²=14.045，P ＜0.05）的比例较高，差异有统计学意义。结论：合并糖尿病的PD患者术后胰瘘发生率较不合并糖尿病患者更高，术后血糖控制不佳增加PD患者术后胰瘘的风险。

Abstract:

Objective ：To investigate the effects of diabetes mellitus(DM) on postoperative complications after pancreaticoduodenectomy(PD). Methods：One hundred and ten patients who underwent PD were retrospectively studied. Patients were classified into the DM group (32 cases) and the non-DM group (78 cases) according to the preoperative status of DM. Differences of postoperative complications， such as pancreatic fistula，were compared. Results：The incidences of pancreatic fistula of the DM group and the non-DM group were 59.4% and 38.5%,respectively.The difference was significant (P ＜0.05＝. No statistical significance (P ＞0.05) was found in the incidences of delayed gastric emptying, infections, biliary fistula , hemorrhage , hospitalization cost, as well as length of stay in hospital. Diabetes mellitus （χ²=4.018，P ＜0.05)and poorly controlled postoperative blood glucose level （χ²=14.045，P ＜0.05)were more common in patients who developed pancreatic fistula. Conclusion：The incidence of pancreatic fistula in patients with DM is higher than those without DM. Postoperative pancreatic fistula is more likely to happen in patients whose postoperative glucose level is poorly controlled.

参考文献/References:

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[9]Xia X, Huang C, Cen G, et al. Preoperative diabetes as a protective factor for pancreatic fistula after pancreaticoduodenectomy: a meta-analysis[J].Hepatobiliary& Pancreatic Diseases International, 2015,14(2):132

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备注/Memo

备注/Memo:

作者简介 王开毫（1990-），男，硕士在读，研究方向：肝胆胰外科；

通信作者：田伟军，E-mail:jonathontian@163.com。

常用功能

更新日期/Last Update: 2017-07-01