|本期目录/Table of Contents|

[1]苏东峰,聂秀玲,孙丽荣.2型糖尿病合并高尿酸血症临床特征及相关危险因素分析[J].天津医科大学学报,2013,19(06):481.
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2型糖尿病合并高尿酸血症临床特征及相关危险因素分析
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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
19
期数:
2013年06期
页码:
481
栏目:
临床医学
出版日期:
2013-11-20

文章信息/Info

Title:
-
作者:
苏东峰聂秀玲孙丽荣
天津医科大学代谢病医院糖尿病痛风科,卫生部激素与发育重点实验室,天津300070
Author(s):
-
关键词:
糖尿病2型高尿酸血症 临床特征危险因素
Keywords:
-
分类号:
R587.2
DOI:
-
文献标志码:
A
摘要:
目的:探讨2型糖尿病合并高尿酸血症临床特征及危险因素。方法:选取2型糖尿病患者421例,根据血尿酸(SUA)水平分为高尿酸(HUA)组118例和正常尿酸(NUA)组303例,测量身高、体质量、血压、空腹静脉血糖(FPG)、血脂、血尿酸、肝肾功能、糖化血红蛋白,24 h尿微量白蛋白(UMA)、总蛋白(UTP)、尿肌酐(UCR)、尿尿酸(UUA)。结果:2型糖尿病合并高尿酸血症患病率为28.03%,HUA组的体质量指数( BMI )、舒张压、TG(甘油三酯)、AST(谷草转氨酶)、GGT(γ-谷氨酰转肽酶)、血肌酐、尿素氮、UCR、UMA、UTP较NUA组明显升高, 而HDL、FEUA 、Ccr均明显低于NUA组。Logistic 回归分析显示体质量指数、TG、血肌酐、尿酸排泄分数、肌酐清除率是 SUA的独立危险因素。结论:糖尿病合并高尿酸血症者存在更明显的肥胖,脂代谢紊乱,肝肾功能损害,是发生高尿酸血症主要原因。
Abstract:
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参考文献/References:

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2013-12-20