|本期目录/Table of Contents|

[1]李凤英,朱铁虹.中年男性2型糖尿病患者促甲状腺激素与尿钙/肌酐比值的相关性研究[J].天津医科大学学报,2014,20(05):389-391.
 LI Feng-ying,ZHU Tie-hong.Relationship between thyroid stimulating hormone and urinary calcium/creatinine excretion in middle-aged man with type 2 diabetes[J].Journal of Tianjin Medical University,2014,20(05):389-391.
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中年男性2型糖尿病患者促甲状腺激素与尿钙/肌酐比值的相关性研究(PDF)
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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
20
期数:
2014年05期
页码:
389-391
栏目:
临床医学
出版日期:
2014-09-20

文章信息/Info

Title:
Relationship between thyroid stimulating hormone and urinary calcium/creatinine excretion in middle-aged man with type 2 diabetes
文章编号:
1006-8147(2014)05-0389-03
作者:
李凤英1 朱铁虹2
(1.天津医科大学研究生院,天津300070;2.天津医科大学总医院内分泌科,天津300052)
Author(s):
LI Feng-ying1ZHU Tie-hong2
(1.Graduate School, Tianjin Medical University, Tianjin 300070,China; 2.Department of Endocrinology, General Hospital, Tianjin Medical University, Tianjin 300052,China)
关键词:
促甲状腺激素尿钙/肌酐比值糖尿病2型
Keywords:
thyroid stimulating hormone urinary calcium/creatinine excretion diabetes mellitus type 2
分类号:
R587.1
DOI:
-
文献标志码:
A
摘要:
目的:探讨中年男性2型糖尿病患者促甲状腺激素与尿钙/肌酐比值的相关性。方法:根据血促甲状腺激素(TSH)水平将516例中年男性2型糖尿病患者分为低TSH组、正常TSH组和高TSH组,测量身高、体质量、血压、空腹血糖、血肌酐、碱性磷酸酶、血钙、血磷、TSH、24 h尿钙、尿磷、尿肌酐。结果:随着TSH水平升高,中年男性2型糖尿病患者尿钙及尿钙/肌酐比值逐步降低(均P趋势<0.05)。多元线性回归分析经年龄、糖尿病病程等因素调整后仍显示TSH是影响尿钙/肌酐比值的相关因素(β=-0.024,P<0.05)。结论:中年男性2型糖尿病患者TSH与尿钙/肌酐比值呈负相关,TSH是影响尿钙排泄率的独立影响因素。
Abstract:
Objective: To investigate the relationship between thyroid stimulating hormone (TSH) and urinary calcium/creatinine excretion in middle-aged man with type 2 diabetes. Methods: Five hundred and sixteen middle-aged man with type 2 diabetes were included in the study. Based on their TSH, these subjects were divided into three groups : low TSH group , normal TSH group and high TSH group . Height,weight,blood pressure,fasting blood glucose,serum creatinine,alkaline phosphatase,serum calcium,serum phosphorus,TSH,24h urinary calcium,urinary phosphorus,urinary creatinine were measured. Results: A relationship of lower calcium and lower urinary calcium/creatinine excretion with increasing TSH, even after adjusting age and diabetic duration, was found ( both Ptrend <0.05). Multiple linear regression analysis showed that TSH could be associated with urinary calcium/creatinine excretion (β=-0.024,P<0.05). Conclusion: TSH has a negative correlation with urinary calcium/creatinine excretion in middle-aged man with type 2 diabetes, and can function as an independent acting factor of urinary calcium excretion rate。

参考文献/References:

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备注/Memo

备注/Memo:
作者简介 李凤英(1968-),女,硕士在读,研究方向:内分泌与代谢病;通信作者:朱铁虹,E-mail:zhutiehong@163.com。
更新日期/Last Update: 2014-09-25