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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:

28卷

期数:

2022年01期

页码:

69-72

栏目:

临床研究

出版日期:

2022-01-20

文章信息/Info

Title:

Correlation analysis and predictive value of metabolic index for coronary heart disease

文章编号:

1006-8147（2022）01-0069-04

作者:

李艳芳; 牛书林; 袁如玉

（天津医科大学第二医院心脏科，天津市心血管病离子与分子机能重点实验室，天津心脏病学研究所，天津 300211）

Author(s):

LI Yan-fang; NIU Shu-lin; YUAN Ru-yu

（Department of Cardiology，The Second Hospital，Tianjin Medical University，Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease，Tianjin Institute of Cardiology，Tianjin 300211，China）

关键词:

冠心病; 代谢性指标; 预测价值; 颈围

Keywords:

coronary heart disease; metabolic index; predictive value; neck circumference

分类号:

R541.4

DOI:

-

文献标志码:

A

摘要:

目的：探讨代谢性指标与冠状动脉粥样硬化性心脏病（冠心病）之间的相关性及预测价值。方法：选取2019年9—12月在天津医科大学第二医院接受冠状动脉造影（冠造）检查的患者313例（男161例、女152例），确诊的212例冠心病患者作为冠心病组，同期冠造检查正常的101例作为正常组，记录患者的基本临床资料及相关检查结果。将高脂血症患者分为冠心病组（131例）和正常组（55名）。比较两种方法下两组患者代谢性指标与冠心病的关系及预测价值。研究不同性别代谢性指标对冠心病的预测价值。结果：冠心病组与正常组间性别、年龄、颈围、腰围、体重指数（BMI）、吸烟史、饮酒史、糖尿病史及甘油三酯差异有统计学意义（t/?字2=13.66、3.45、4.72、2.67、3.76、18.37、4.52、8.73、2.28；均P<0.05）。伴有高脂血症的冠心病组与正常组间年龄、颈围、腰围、BMI、腰臀比、吸烟史及总胆固醇差异有统计学意义（t/?字2=2.13、3.83、2.53、2.89、2.67、8.70、-2.87；均P<0.05）。受试者工作特征（ROC）曲线示颈围较其余代谢性指标对冠心病预测更有意义（P<0.05）。结论：代谢性指标与冠心病密切相关，颈围对冠心病更具有预测价值。

Abstract:

Objective：To investigate the correlation and predictive value between coronary heart disease（CHD） and metabolic indexes. Methods: A total of 313 patients（male 161，female 152） receiving coronary angiography in the Second Hospital of Tianjin Medical University from September to December were recruited. The 212 confirmed CHD patients were treated as the CHD group，and the 101 patients with normal coronary angiography were treated as the normal group. Basic clinical data and relevant examination results were recorded. The patients with hyperlipidemia in the general population were divided into CHD group（131 cases） and normal group（55 cases）.The relationship between metabolic indexes and CHD and its predictive value were compared between the two groups. In addition，the predictive value of metabolic indexes for CHD was studied by gender. Results：Gender，age，neck circumference，waist circumference，BMI，smoking and drinking history，diabetes history and triglyceride between CHD group and normal group had statistical significance in the total population（t/?字2=13.66，3.45，4.72，2.67，3.76，18.37，4.52，8.73，2.28；all P<0.05）.Age，neck circumference，waist circumference，BMI，waist-hip ratio，smoking history，and total cholesterol was statistically significant difference between CHD group with hyperlipidemia and normal group（t/?字2=2.13，3.83，2.53，2.89，2.67，8.70，-2.87；all P<0.05）.ROC curve showed that neck circumference was more significant than other metabolic indexes in predicting CHD（P<0.05）.Conclusion：The metabolic indexes are closely related to CHD，and the neck circumference has more predictive value CHD.

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备注/Memo

备注/Memo:

基金项目 国家自然科学基金（81420108003）；天津市自然科学基金（18JCQNJC82600）
作者简介 李艳芳（1993-），女，硕士在读，研究方向：心血管内科；通信作者：袁如玉，E-mail：yuanruyu2014@126.com。

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更新日期/Last Update: 2022-01-20