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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:

22卷

期数:

2016年03期

页码:

234-237

栏目:

临床医学

出版日期:

2016-05-20

文章信息/Info

Title:

Impact of body mass index on prognosis in patients with Acute ST-segment elevation Myocardial Infarction after emergency percutaneous coronary intervention during Super urgent period

文章编号:

1006-8147（2016）03-0234-04

作者:

王东昕; 崔占前; 郭星梅; 徐延敏

(天津医科大学第二医院心脏科,天津 300211)

Author(s):

?WANG Dong -xin ; CUI Zhan -qian ; GUO Xing -mei; XU Yan -min

(Department of Cardiology ,The Second Hospital ,Tianjin Medical University ,Tianjin Institute of Cardiology,Tianjin 300211, China)

关键词:

急性心肌梗死; 体质量指数; 肌钙蛋白I; 预后; 主要心血管不良事件

Keywords:

acute myocardial infarction;  body mass index;  troponin I;  outcomes; major adverse cardiac events

分类号:

R542.2+2

DOI:

-

文献标志码:

A

摘要:

目的：探讨体质量指数(BMI)对入院后行急诊经皮腔内冠状动脉成形术（PCI）的超急期急性ST段抬高型心肌梗死(STEMI)患者预后的影响。方法：连续入选入院后行急诊PCI治疗的超急期STEMI患者353例，根据BMI水平分为3组，BMI<24 kg/m2者为A组(115例)，BMI在24.0～28.0 kg/m2之间者为B组(133例)，BMI≥28.0 kg/m2者为C组(105例)。记录院内有无主要不良心血管事件（MACE）的发生，分析3组间差异有无统计学意义。结果：（1）合并高血压病史、氢氯吡格雷负荷剂量、替罗非班使用率在3组间差异有统计学意义(P<0.05)。（2）总胆固醇（TC）水平C组高于A、B两组，差异有统计学意义(P＜0.05)，甘油三酯（TG）水平C组高于A组，差异有统计学意义(P＜0.05)。（3）自发再通率C组高于A组，差异有统计学意义(P＜0.05),无复流发生率在C组高于A组(P＜0.05)。（4）院内MACE发生率C组明显高于A、B两组(P＜0.05)；院内死亡率3组间差异无统计学意义(P＞0.05)。结论：对于入院行急诊PCI的超急期STEMI患者肥胖能增加院内MACE的发生率，但超重和肥胖并不增加院内死亡率。

Abstract:

Objective：To assess the impact of body mass index(BMI)on prognosis in patients with Acute ST-segment elevation myocardial infarction after emergency percutaneous coronary intervention during Super urgent period. Methods： Three hundred and fifty-three consecutive patients after emergency percutaneous coronary intervention were included. Patients were divided into 3 Groups according to baseline BMI: Group A, normal weight(BMI<24kg/m2,n=115),Group B, overweight(24.0～28.0 kg/m²,n=133), Group C, obese(BMI≥28.0 kg/m²,n=105).Major adverse cardiac events (MACE) during in-hospital periods were recorded. Presence of any significant differences among three groups was statistically analyzed. Results：（1）There were significant differences in the prevalence of hypertension ,the load dosage of clopidogrel and the usage of tirofiban(P<0.05) among three groups.（2）Serum total cholesterol(TC) levels in obese group was significantly higher than normal and overweight groups (P<0.05).Serum triglycerides(TG)levels in obese group was significantly higher than normal (P<0.05).（3）Spontaneous reperfusion in obese group was significantly higher than normal(P<0.05).The prevalence of no-reflow in obese was also significantly higher than normal group(P<0.05).（4）The incidence rate of in-hospital MACE in obese was significantly higher than normal and overweight groups(P<0.05).The difference in the incidence of in-hospital mortality among the three groups was not statistically significant (P>0.05).Conclusion：For ASTEMI hospitalized patients after emergency percutaneous coronary intervention during super urgent period, overweight and obesity may be independent of in-hospital mortality rates, although obesity could be associated with the incidence of in-hospital MACE.

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备注/Memo

备注/Memo:

作者简介 王东昕（1987-），女，硕士在读，研究方向：心血管内科学；

通信作者：徐延敏，E-mail: xuyanminphd@aliyun.com。

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更新日期/Last Update: 2016-05-25