|本期目录/Table of Contents|

[1]魏强,齐灿,罗飞,等.转移性去势抵抗性前列腺癌患者多西他赛化疗的预后分析[J].天津医科大学学报,2013,19(05):390-392.
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转移性去势抵抗性前列腺癌患者多西他赛化疗的预后分析
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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
19卷
期数:
2013年05期
页码:
390-392
栏目:
临床医学
出版日期:
2013-09-20

文章信息/Info

Title:
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作者:
魏强;齐灿;罗飞;张志宏;徐勇;
天津医科大学第二医院泌尿外科,天津市泌尿外科研究所;
Author(s):
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关键词:
前列腺癌去势抵抗性多西他赛预后碱性磷酸酶
Keywords:
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分类号:
-
DOI:
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文献标志码:
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摘要:
目的:探讨影响转移性去势抵抗性前列腺癌(mCRPC)患者多西他赛化疗后总生存期(OS)的预后因素。方法:选择性回顾性分析96例接受多西他赛化疗的mCRPC患者的临床资料,对相关的临床因素分别进行单因素及多因素分析。结果:96例患者中63例死亡,全组患者中位OS为26.2个月。单因素分析显示,ECOG评分、基线前列腺特异抗原(PSA)值、骨转移、基线碱性磷酸酶(ALP)浓度及化疗周期数与化疗后OS相关(P<0.05)。多因素分析显示,基线ALP浓度≥120IU/L、基线PSA值≥60ng/mL、化疗周期数<10是较短OS的独立预后因素(P<0.05)。结论:多西他赛治疗mCRPC可以获得较好的总生存率,化疗前基线ALP浓度、基线PSA值及化疗周期数是影响预后的独立因素。更多还原
Abstract:
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参考文献/References:

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2013-10-20