|本期目录/Table of Contents|

[1]刘博,明浩朗,江煜星,等.脊髓室管膜瘤的研究进展[J].天津医科大学学报,2024,30(05):471-475.[doi:10.20135/j.issn.1006-8147.2024.05.0471]
点击复制

脊髓室管膜瘤的研究进展(PDF)
分享到:

《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
30卷
期数:
2024年05期
页码:
471-475
栏目:
综述
出版日期:
2024-09-25

文章信息/Info

Title:
-
文章编号:
1006-8147(2024)05-0471-05
作者:
刘博明浩朗江煜星朱涛 综述王增光 审校
(天津医科大学总医院神经外科,天津 300052)
Author(s):
-
关键词:
脊髓室管膜瘤病理学分子预后
Keywords:
-
分类号:
R739.42
DOI:
10.20135/j.issn.1006-8147.2024.05.0471
文献标志码:
A
摘要:
脊髓室管膜瘤是中枢神经系统上皮性肿瘤,也属于最常见的脊髓髓内肿瘤之一,发生在所有年龄段。与颅内室管膜瘤相比,脊髓室管膜瘤的发生率较低,预后较好。这些肿瘤具有多种类型和亚型的广泛异质性。由于肿瘤的异质性,患者的预后存在明显的个体差异。因此,本文从特征、诊断及鉴别诊断、治疗方案及预后等方面对脊髓室管膜瘤进行综述。
Abstract:
-

参考文献/References:

[1] SCOTT K R,GENER M A,REPNIKOVA EA. Pediatric spinal ependymoma with chromothripsis of chromosome 6:a case report and review of the literature[J]. J Med Case Rep,2024,18(1):95.
[2] MCGUIRE C S,SAINANI K L,FISHER P G. Incidence patterns for ependymoma:a surveillance,epidemiology,and end results study[J]. J Neurosurg,2009,110(4):725-729.
[3] LOUIS D N,PERRY A,REIFENBERGER G,et al. The 2016 World Health Organization Classification of Tumors of the Central Nervous System:a summary[J]. Acta Neuropathol,2016,131(6):803-820.
[4] ELLISON D W,ALDAPE K D,CAPPER D,et al. cIMPACT-NOW update 7:advancing the molecular classification of ependymal tumors[J]. Brain Pathol,2020,30(5):863-866.
[5] LOUIS D N,PERRY A,WESSELING P,et al. The 2021 WHO Class-ification of Tumors of the Central Nervous System:a summary[J]. Neuro Oncol,2021,23(8):1231-1251.
[6] 潘灏,杨学军,李志勇,等. 2021年世界卫生组织中枢神经系统肿瘤分类(第五版)室管膜肿瘤分类解读[J].中国现代神经疾病杂志,2021,21(9):809-816.
[7] RAFFELD M,ABDULLAEV Z,PACK S D,et al. High level MYCN amplification and distinct methylation signature define an aggressive sub-type of spinal cord ependymoma[J]. Acta Neuropathol Commun,2020,8(1):101.
[8] GHASEMI D R,SILL M,OKONECHNIKOV K,et al. MYCN amplification drives an aggressive form of spinal ependymoma[J]. Acta Neuropathol,2019,138(6):1075-1089.
[9] SWANSON A A,RAGHUNATHAN A,JENKINS R B,et al. Spinal cord ependymomas with MYCN amplification show aggressive clinical behavior[J]. J Neuropathol Exp Neurol,2019,78(9):791-797.
[10] LOPEZ-RIVERA V,DONO A,ABDELKHALEQ R,et al. Treatment trends and overall survival in patients with grade Ⅱ/Ⅲ ependymoma:the role of tumor grade and location[J]. Clin Neurol Neurosurg,2020,199:106282.
[11] LI X,ANDRUSIVOVA Z,CZARNEWSKI P,et al. Profiling spatiotemporal gene expression of the developing human spinal cord and implications for ependymoma origin[J]. Nat Neurosci,2023,26(5):891-901.
[12] OMERHODZIC I,POJSKIC M,ROTIM K,et al. Myxopapillary ependymoma of the spinal cord in adults:a report of personal series and review of literature[J]. Acta Clin Croat,2020,59(2):329-337.
[13] CELANO E,SALEHANI A,MALCOLM J G,et al. Spinal cord ependymoma:a review of the literature and case series of ten patients[J]. J Neurooncol,2016,128(3):377-386.
[14] AZZAZI A,ALMEKAWI S,ZEIN M. Lumbar disc nucleoplasty using coblation technology:clinical outcome[J]. J Neurointerv Surg,2011,3(3):288-292.
[15] ENGELHARD H H,VILLANO J L,PORTER K R,et al. Clinical presentation,histology,and treatment in 430 patients with primary tumors of the spinal cord,spinal meninges,or cauda equina[J]. J Neurosurg Spine,2010,13(1):67-77.
[16] CAGE T A,CLARK A J,ARANDA D,et al. A systematic review of treatment outcomes in pediatric patients with intracranial ependymomas[J]. J Neurosurg Pediatr,2013,11(6):673-681.
[17] 王金龙,刘亚军,郭运发,等. 脊髓室管膜瘤的临床特征及治疗方法分析[J].中华神经医学杂志,2017,22(11):1153-1157.
[18] KEIL V C,SCHMITT A J,MARTIN S C,et al. Optimising treatment strategies in spinal ependymoma based on 20 years of experience at asingle centre[J]. J Clin Neurosci,2016,29:52-58.
[19] TAKAMI T,NAITO K,YAMAGATA T,et al. Surgical management of spinal intramedullary tumors:radical and safe strategy for benign tumors[J]. Neurol Med Chir (Tokyo),2015,55(4):317-327.
[20] 陆南,陈超,高干,等. 术中体感诱发电位监测在椎管内肿瘤手术中的预测价值[J].中国矫形外科杂志,2018,26(7):619-621.
[21] 肖群根,郭翔,陶安宇,等. 术中超声在脊髓髓内室管膜瘤和星形细胞瘤外科治疗中的应用[J]. 中华神经外科杂志,2020,(2):156-161.
[22] 孙振兴,王贵怀,王劲,等. 脊髓室管膜瘤患者术中黄荧光技术的应用[J].中华神经外科杂志,2017,33(2):128-132.
[23] EROES C A,ZAUSINGER S,KRETH F W,et al. Intramedullary low grade astrocytoma and ependymoma. Surgical results and predicting factors for clinical outcome[J]. Acta Neurochir(Wien),2010,152(4):611-618.
[24] LIN Y,SMITH Z A,WONG A P,et al. Predictors of survival in patients with spinal ependymoma[J]. Neurol Res,2015,37(7):650-655.
[25] LIU T,YANG C,DENG X,et al. Clinical characteristics and surgical outcomes of spinal myxopapillary ependymomas[J]. Neurosurg Rev,2020,43(5):1351-1356.
[26] MONTERO A S,TRAN S,AMELOT A,et al. Clinical characteristics and long-term surgical outcome of spinal myxopapillary ependy-moma:a French cohort of 101 patients[J]. J Neurooncol,2021,152(3):491-499.
[27] FELDMAN W B,CLARK A J,SAFAEE M,et al. Tumor control aftersurgery for spinal myxopapillary ependymomas:distinct outcomes in adults versus children:a systematic review[J]. J Neurosurg Spine,2013,19(4):471-476.
[28] OH M C,IVAN M E,SUN M Z,et al. Adjuvant radiotherapy delaysrecurrence following subtotal resection of spinal cord ependymomas[J]. Neuro Oncol,2013,15(2):208-215.
[29] BATES J E,CHOI G,MILANO M T. Myxopapillary ependymoma:a SEER analysis of epidemiology and outcomes[J]. J Neurooncol,2016, 129(2):251-258.
[30] AKYUREK S,CHANG E L,YU T K,et al. Spinal myxopapillary ependymoma outcomes in patients treated with surgery and radiotherapy at M.D. Anderson Cancer Center[J]. J Neurooncol,2006,80(2):177-183.
[31] KIM W H,YOON S H,KIM C Y,et al. Temozolomide for malignant primary spinal cord glioma:an experience of six cases and a literature review[J].J Neurooncol,2011,101(2):247-254.
[32] LORGIS V,VARBEDIAN O,GHIRINGHELLI F. Metronomic cyclophosphamide with cisplatin and bevacizumab:a new chemo-therapeutic regimen for refractory anaplastic ependymoma[J]. Anticancer Res,20121,32(11):5067-5070.
[33] KALAMARIDES M,ESSAYED W,LEJEUNE J P,et al. Spinal ependymomas in NF2:a surgical disease[J]. J Neurooncol,2018, 136(3):605-611.
[34] KATRINA A M,SHAZIA K A,EVANS D G,et al. The response of spinal cord ependymomas to bevacizumab in patients with neurofibromatosis type 2[J]. J Neurosurg Spine,2017, 26(4):474-482.
[35] BLAKELEY J O,YE X,DUDA D G,et al. Efficacy and biomarker study of bevacizumab for hearing loss resulting from neurofibromatosis type 2-associated vestibular schwannomas[J]. J Clin Oncol,2016,34(14):1669-1675.
[36] CHAMBERLAIN M C. Ependymomas[J]. Curr Neurol Neurosci Rep,2003,3(3):193-199.
[37] SALEH A H,SAMUEL N,JURASCHKA K,et al. The biology of ependymomas and emerging novel therapies[J]. Nat Rev Cancer,2022,22(4):208-222.
[38] GATTO L,FRANCESCHI E,DI NUNNO V,et al. Engineered CAR-T and novel CAR-based therapies to fight the immune evasion of glioblas-toma:gutta cavat lapidem[J]. Expert Rev Anticancer Ther,2021,21(12):1333-1353.
[39] GATTO L,NUNNO V D,FRANCESCHI E,et al. Chimeric antigenreceptor macrophage for glioblastoma immunotherapy:the way forward[J]. Immunotherapy,2021,13(11):879-883.
[40] GATTA G,BOTTA L,ROSSI S,et al. Childhood cancer survival in Europe 1999-2007:results of EUROCARE-5a populationbased study[J]. Lancet Oncol,2014,15(1):35-47.
[41] 范雁东,孙宏杰,马木提江·木尔提扎,等. 显微手术治疗脊髓室管膜瘤的临床效果及其预后影响因素分析[J]. 中外医学研究,2022,20(17):45-48.
[42] 卞艺颖,陈伟鹏,李战战,等. 影响颅内室管膜瘤患者生存和预后的相关因素分析[J]. 中国肿瘤临床,2019,46(3):138-144.
[43] 王文涛,曹宁,张国来.表皮生长因子受体在室管膜瘤中的表达及与患者预后的关系[J]. 癌症进展,2022,20(11):1183-1186.
[44] 曹春香,徐晓婷,周菊英. 放疗后室管膜肿瘤患者的生存预后因素分析[J]. 中国血液流变学杂志,2017,27(3):291-293.
[45] CERRETTI G,PESSINA F,FRANCESCHI E,et al. Spinal ependymoma in adults:from molecular advances to new treatment perspectives[J]. Front Oncol,2023,13:1301179.
[46] KONG L Y,HAIDER A S,LIEBELT B D,et al. Therapeutic target in subependymoma[J].Neuroimmunol,2014,277(1~2):168-175.

相似文献/References:

[1]黄雪强,王 一,刘高瑞,等.囊性肾细胞癌的诊治分析[J].天津医科大学学报,2015,21(03):68.
 HUANG Xue-qiang,WANG Yi,LIU Gao-rui,et al.Diagnosis and treatment of cystic renal cell carcinoma[J].Journal of Tianjin Medical University,2015,21(05):68.
[2]黄雪强,王 一,刘高瑞,等.囊性肾细胞癌的诊治分析[J].天津医科大学学报,2015,21(01):68.
 HUANG Xue-qiang,WANG Yi,LIU Gao-rui,et al.Diagnosis and treatment of cystic renal cell carcinoma[J].Journal of Tianjin Medical University,2015,21(05):68.
[3]赵 云,赵 红,张 蕾,等.12例眼眶孤立性纤维性肿瘤临床病理特征分析[J].天津医科大学学报,2016,22(01):68.
[4]董有文综述,徐文贵审校.硬化性肺泡细胞瘤的影像及临床特征研究进展[J].天津医科大学学报,2016,22(05):463.
[5]秦振邦,王冬冬,杨 盼,等.肾粘液样小管状和梭形细胞癌的研究分析[J].天津医科大学学报,2017,23(01):43.
[6]杨菊菊,董丽霞,曹 洁.HIV阴性的肺隐球菌病患者13例临床分析[J].天津医科大学学报,2017,23(01):78.
[7]郭玉虹,孙燕,孙保存.44例EBV相关性胃癌临床病理分析[J].天津医科大学学报,2019,25(06):634.
 GUO Yu-hong,SUN Yan,SUN Bao-cun.To investigate the pathological features of EBV-associated gastric cancer[J].Journal of Tianjin Medical University,2019,25(05):634.

备注/Memo

备注/Memo:
基金项目 国家重点研发计划项目(2022YFF1202500)
作者简介 刘博(1974-),男,副主任医师,博士,研究方向:神经外科;通信作者:刘博,E-mail:stanleyliubo@126.com。
更新日期/Last Update: 2024-09-20