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[1]孙超,余兰,李蓉蓉,等.1990—2019年中国和日本食管癌疾病负担变化趋势的比较分析[J].天津医科大学学报,2024,30(01):46-50,55.[doi:10.20135/j.issn.1006-8147.2024.01.0046]
　SUN Chao,YU Lan,LI Rongrong,et al.A comparative analysis of trends in the disease burden of esophageal cancer in China and Japan from 1990 to 2019[J].Journal of Tianjin Medical University,2024,30(01):46-50,55.[doi:10.20135/j.issn.1006-8147.2024.01.0046]
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1990—2019年中国和日本食管癌疾病负担变化趋势的比较分析(PDF)
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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
30卷
期数:
2024年01期
页码:
46-50,55
栏目:
临床医学
出版日期:
2024-01-01

文章信息/Info

Title:
A comparative analysis of trends in the disease burden of esophageal cancer in China and Japan from 1990 to 2019
文章编号:
1006-8147(2024)01-0046-06
作者:
孙超1; 余兰2; 李蓉蓉2; 张强2; 张绪梅2; 杨学礼2
（1. 天津市西青区杨柳青镇社区卫生服务中心，天津300380；2. 天津医科大学公共卫生学院，天津300070）
Author(s):
SUN Chao1; YU Lan2; LI Rongrong2; ZHANG Qiang2; ZHANG Xumei2; YANG Xueli2
（1.Yangliuqing Community Health Service Center，Tianjin 300380，China；2.School of Public Health，Tianjin Medical University，Tianjin 300070，China）
关键词:
食管癌; 中国; 日本; 疾病负担; 危险因素
Keywords:
esophageal cancer; China; Japan; burden of disease; risk factor
分类号:
R735.1
DOI:
10.20135/j.issn.1006-8147.2024.01.0046
文献标志码:
A
摘要:
目的：描述和分析1990—2019年中国和日本食管癌发病、死亡和伤残调整寿命年（DALYs）状况的变化趋势，比较两国食管癌疾病负担及相关危险因素的变化和差异。方法：利用2019年全球疾病负担数据，采用发病率、死亡率、DALYs率和年龄标化率以及平均年度变化百分比（AAPC）对两国食管癌疾病负担及变化趋势进行比较分析。应用食管癌各危险因素的人群归因百分比（PAF）分析不同危险因素对两国食管癌疾病负担的贡献。结果：总体上，中国食管癌的疾病负担大于日本。2019年中国食管癌年龄标化发病率、标化死亡率和标化DALYs率分别为13.90/10万、13.15/10万和277.60/10万，日本分别为6.45/10万、3.91/10万和85.81/10万。食管癌的疾病负担存在性别差异，两国男性食管癌疾病负担均明显大于女性。另外，从1990年至2019年，中国食管癌年龄标化发病率（AAPC=-1.4%，P<0.001）、标化死亡率（AAPC=-1.8%，P<0.001）和标化DALYs率（AAPC=-2.1%，P<0.001）整体呈现下降趋势，而日本食管癌年龄标化发病率（AAPC=-0.1%，P=0.006）、标化死亡率（AAPC=-0.8%，P<0.001）和标化DALYs率（AAPC=-0.9%，P<0.001）呈现稳中略降的趋势。吸烟、饮酒是导致两国食管癌疾病负担的主要危险因素。结论：1990年至2019年，中国和日本食管癌疾病负担均有所下降，但我国食管癌疾病负担仍高于日本。吸烟、饮酒是导致两国食管癌疾病负担的重点危险因素。
Abstract:
Objective：The study was aimed to describe and analyze the trends of incidence，mortality and disability-adjusted life-years （DALYs） rate for esophageal cancer （EC） in China and Japan from 1990 to 2019. Furthermore，the study compared the changes and differences in the disease burden and related risk factors of EC in the two countries. Methods：Using the 2019 Global Burden of Disease（GBD 2019） data，the trends in disease burden and risk factors for EC were analyzed by incidence，mortality，DALYs rate and their corresponding age-standardized rate（ASR），as well as calculating average annual percentage change（AAPC）. Population attributable faction（PAF） of various risk factors for esophageal cancer was used to analyze the contribution of different risk factors to the burden of EC in both countries. Results：Overall，the disease burden of EC in China was greater than that in Japan. In 2019，the age-standardized inci-dence rate（ASIR），age-standardized mortality rate（ASMR） and age-standardized DALYs rate of EC in China were 13.90/100 000， 13.15/100 000 and 277.60/100 000，respectively. The ASIR，ASMR and age-standardized DALYs rate of EC in Japan were 6.45/100 000，3.91/100 000 and 85.81/100 000，respectively. There was a gender difference in the burden of esophageal cancer，and the disease burden of esophageal cancer in men is significantly greater than that in women in both countries. Besides，from 1990 to 2019，the ASIR（AAPC= -1.4%，P<0.001），ASMR（AAPC= -1.8%，P<0.001） and age-standardized DALYs rate（AAPC=-2.1%，P<0.001） of EC in China showed an overall downward trend，while the ASIR（AAPC= -0.1%，P=0.006），ASMR（AAPC= -0.8%，P<0.001） and age-standardized DALYs rate（AAPC= -0.9%，P<0.001） of EC in Japan showed a steady trend with a slight decline. Smoking and alcohol consumption were the top two risk factors for the disease burden of esophageal cancer in both China and Japan. Conclusion：From 1990 to 2019，the disease burden of esophageal cancer in both China and Japan has decreased，but it is still higher in China than that in Japan. Smoking and alcohol consumption are key risk factors for the disease burden of EC in both countries.

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备注/Memo

备注/Memo:
作者简介 孙超（1985-），男，主管检验师，学士，研究方向：基层慢病管理；通信作者：杨学礼，E-mail：yangxueli2019@tmu.edu.cn。
更新日期/Last Update: 2024-01-01