|本期目录/Table of Contents|

[1]索睿,郝天旭,茹仙古丽·吾买尔 综述,等.间充质干细胞来源的外泌体治疗哮喘的研究进展[J].天津医科大学学报,2023,29(06):673-676.
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间充质干细胞来源的外泌体治疗哮喘的研究进展(PDF)
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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
29卷
期数:
2023年06期
页码:
673-676
栏目:
综述
出版日期:
2023-11-20

文章信息/Info

Title:
-
文章编号:
1006-8147(2023) 06-0673-04
作者:
索睿; 郝天旭; 茹仙古丽·吾买尔 综述; 赵晓赟 审校
（天津医科大学胸科临床学院，天津300222）
Author(s):
-
关键词:
哮喘; 间充质干细胞; 外泌体; 气道重塑
Keywords:
-
分类号:
R562.2+5
DOI:
-
文献标志码:
A
摘要:
哮喘是由多种细胞（如嗜酸性粒细胞、肥大细胞、T细胞、中性粒细胞、气道上皮细胞等）和细胞组分参与的气道慢性炎症性疾病，长期慢性气道炎症导致气道高反应性、可逆性气流受限及气道重塑。间充质干细胞（MSCs）对改善哮喘小鼠的气道重塑有较好的疗效，其释放的外泌体可能在治疗过程中发挥重要的作用。外泌体是细胞间通讯的重要载体，在细胞间转运具有生物活性的脂质、核酸及蛋白质等，从而改变靶细胞的生物学功能。MSCs来源的外泌体具有抗炎、免疫调节及促进组织修复和再生等作用，是哮喘治疗的新靶点。
Abstract:
-

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备注/Memo

备注/Memo:
基金项目 天津市医学重点学科（专科）建设项目（TKYXZDXK-049A）；天津市卫生健康科技项目（KJ20015）；天津市津南区科技计划项目（20200116）
作者简介 索睿（1998-），女，硕士在读，研究方向：呼吸系统疾病；通信作者：赵晓赟，E-mail：zxydoctor@163.com。
更新日期/Last Update: 2023-12-01