|本期目录/Table of Contents|

[1]林淑萍,代红磊,房宏伟,等.慢性鼻窦炎患者中变应性因素的临床研究[J].天津医科大学学报,2017,23(03):259-262.
 LIN Shu-ping,DAI Hong-lei,FANG Hong-wei,et al.Clinical study of? allergic factors in patients with chronic rhinosinusitis[J].Journal of Tianjin Medical University,2017,23(03):259-262.
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慢性鼻窦炎患者中变应性因素的临床研究(PDF)
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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
23卷
期数:
2017年03期
页码:
259-262
栏目:
临床医学
出版日期:
2017-05-18

文章信息/Info

Title:
Clinical study of? allergic factors in patients with chronic rhinosinusitis
文章编号:
1006-8147(2017)03-0259-04
作者:
林淑萍代红磊房宏伟孙士铭
(天津医科大学总医院耳鼻咽喉头颈外科,天津 300052)
Author(s):
LIN Shu-pingDAI Hong-leiFANG Hong-weiSUN Shi-ming
(Department of Otorhinolaryngology Head and Neck Surgery,General Hospital ,Tianjin Medical University,Tianjin 300052,China)
关键词:
慢性鼻-鼻窦炎鼻息肉IgE嗜酸性粒细胞过敏原
Keywords:
chronic rhinosinusitis nasal polyps IgE eosinophils allergen
分类号:
R765.4+1
DOI:
-
文献标志码:
A
摘要:
目的:探讨慢性鼻-鼻窦炎(CRS)的病因与变应性因素的关系。 方法:选取97例CRS患者为试验组,并按照1997年海口标准进行分型(I型30例,Ⅱ型32例,Ⅲ型35例),20例鼻中隔偏曲患者为对照组,两组之间分别进行血清学指标检测,以SPSS20.0统计软件进行统计学分析。 结果:(1)与对照组相比,外周血嗜酸性粒细胞、血清总IgE(TIgE)、血清特异性IgE(sIgE)在I型CRS患者中的表达差异无统计学意义(P>0.05),在Ⅱ、Ⅲ型CRS患者中表达差异有统计学意义(P<0.05); (2)97例CRS患者中变应原检测阳性结果53例; (3)67例II、III型CRS患者鼻息肉组织切片结果显示有52例为嗜酸性粒细胞浸润,其中III型患者居多。 结论:CRS与变态反应有一定的相关性,抗过敏治疗可能预防或降低CRS的发生。
Abstract:
?Objective: To investigate the correlation between the etiology of chronic rhinosinusitis (CRS)and allergic factors. Methods: Ninety-seven cases of patients with CRS as the experimental group were selected and classified by the Haikou standard in1997(type I 30 cases,type II 32 cases, type Ⅲ 35 cases),20 cases of patients with nasal septum deviation (except allergy history) as the control group,and related serology testing was performed. SPSS20.0 software was used to analyze the data. Results: 1 Compared with control group, the peripheral blood eosinophilia, serum total IgE, serum specific IgE expression in type I CRS were not significantly different (P > 0.05), but expression in type II and Ⅲ patients showed significant difference(P < 0.05). (2) In 97 cases of patients with CRS, allergen result was 53. (3) In 67 cases of type II and III CRS, pathological results showed that there were 52 cases of eosinophilic infiltration, and the majority of patients were type III patients. Conclusion: CRS has certain correlation with allergic reaction and appropriate allergic treatment may prevent or reduce the occurrence of CRS.

参考文献/References:

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备注/Memo

备注/Memo:

作者简介 林淑萍(1987-),女,硕士在读,研究方向:耳鼻咽喉科学;通信作者:孙士铭,Email:sun--_shiming@163.com



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更新日期/Last Update: 2017-05-18