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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:

22卷

期数:

2016年04期

页码:

322-324

栏目:

临床医学

出版日期:

2016-07-19

文章信息/Info

Title:

Efficacy of short-medium term and low dose inhalation of corticosteroids in treatment of asthma and its effect on growth in children

文章编号:

1006-8147（2016）04-0322-03

作者:

周秋梅; 刘长山

(天津医科大学第二医院儿科 ,天津 300211)

Author(s):

ZHOU Qiu-mei;  LIU Chang-shan

(Department of Pediatrics ,The Second Hospital, Tianjin Medical University ,Tianjin 300211,China)

关键词:

哮喘; 吸入糖皮质激素; 生长速率; 体质量指数;  儿童

Keywords:

asthma;  inhalation of corticosteroid;  growth velocity;  body mass index;  child

分类号:

R725.6

DOI:

-

文献标志码:

A

摘要:

目的：探讨中短程低剂量持续吸入糖皮质激素（ICS）对哮喘儿童身高及体质量的影响。方法：观察64例5～14岁中重度持续哮喘儿童经布地奈德福莫特罗治疗前、治疗12周、24周及52周后的身高、体质量及肺功能值并计算生长速率及体质量指数，同54例正常对照组儿童进行比较。结果：哮喘儿童生长速率及体质量指数在治疗后12、24周及52周后同正常对照组相比均无统计学意义（P>0.05），肺功能较治疗前改善明显。结论：中短程低剂量持续ICS治疗对哮喘儿童生长速率及体质量指数无明显抑制，且能有效改善哮喘儿童肺功能。

Abstract:

Objective：To observe the efficacy of short-medium term and low dose inhalation of corticosteroids(ICS) in the treatment of bronchial asthma as well as its effect on growth and development in children. Methods：A total of 64 children diagnosed with bronchial asthma were assigned to treatment and 54 normal children were control group. Comparisons of main pulmonary function indicators, growth velocity(GV) and body mass index (BMI ) between the two groups were carried out before treatment and at 12,24 and 52 weeks after treatment. Results：At 12,24 and 52 weeks after the treatment, the asthma group significantly increased pulmonary function indicators (P<0.05). The GV and BMI showed no significant differences between the two groups at12,24 and 52 weeks after treatment (P>0.05). Conclusion：Low dose ICS for one year may have no marked effect on the growth and development of children with asthma, and could enhance pulmonary function in those children.

参考文献/References:

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备注/Memo

备注/Memo:

作者简介 周秋梅(1987-)，女，硕士在读，研究方向：儿童支气管哮喘；通信作者：刘长山：chshliu@eyou.com。

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更新日期/Last Update: 2016-07-13