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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:

22卷

期数:

2016年06期

页码:

522-524

栏目:

临床医学

出版日期:

2016-11-20

文章信息/Info

Title:

Relationship between plasma leves B-type natriuretic peptide and cardiac structure in patients with different types of atrial fibrillation

文章编号:

1006-8147（2016）06-0522-3

作者:

刘运龄; 赵艳淑; 刘恩照; 赵 珺; 刘 彤; 许 纲

(天津医科大学第二医院心内科 ,天津300211)

Author(s):

LIU Yun-ling; ZHAO Yan-shu; LIU En-zhao; ZHAO Jun;  LIU Tong; XU Gang

(Department of Cardiology,The Second Hospital ，Tianjin Medical University,Tianjin 300211,China)

关键词:

心房颤动; B型钠尿肽; 左房内径; 左室射血分数

Keywords:

atrial fibrillation;  B-type natriuretic peptide;  left atrial diameter ;  left ventricular ejection fraction

分类号:

R541.7

DOI:

-

文献标志码:

A

摘要:

目的：比较不同类型房颤患者血浆中B型钠尿肽（BNP）水平及心脏结构变化。方法：顺序入选阵发性房颤患者35例，持续性房颤患者30例，另设无房颤患者30例作为对照组。详细记录各组患者基线资料、血浆BNP水平以及超声心动图测量数据。结果：持续性房颤组患者血浆BNP平均水平明显高于阵发性房颤组（P<0.001），且这两组患者血浆BNP平均水平均明显高于对照组患者（P <0.001）。3组患者间左心房内径（LAD）（P＜0.001）及右心室舒张末期内径（RVDd）（P= 0.023）存在显著差异。血浆BNP水平与超声指标LAD呈正相关（r = 0.419，P<0.001）。结论：血浆BNP水平随房颤进展而升高，并与房颤患者LAD呈显著正相关。

?

Abstract:

Objective: To analyze the risk factors related to plasma levels of BNP in patients with different types of atrial fibrillation（AF）. Methods:Sixty-five patients with AF were divided into paroxysmal AF group (n=35) and persistent AF group (n=30), and 30 patients without AF were included as control. Detailed information were recorded including the basic characteristics of patients, biochemical parameters, the levels of plasma BNP and transthoracic echocardiography indices. Results: The BNP level in patients with persistent AFgroup was significantly higher than that in paroxysmal AF group (BNP：397.70 ± 335.91vs215.17 ± 212.66，P<0.001), and the BNP level in the two groups with AF was higher than control group

(63.93 ± 69.78, P <0.001). The blood BNP levels were positively correlated with LAD (r=0.419, P <0.001). Conclusion: The plasma BNP levels tend to increase with the development of atrial fibrillation, and are significantly positively correlated with LAD in patients with atrial fibrillation.

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备注/Memo

备注/Memo:

作者简介 刘运龄（1991-），女，硕士在读，研究方向：心血管内科；通信作者：刘恩照，E-mail:liu_ezh@126.com。

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更新日期/Last Update: 2016-11-25