[1]景彩萍,何静子,魏晓丽.炎症因子IL-1β、IL-8、TNF-α与乳腺癌的关系[J].延安大学学报:医学科学版,2014(3):61 [2]Inoue J I, Gohda J, Akiyama T, et al. NF-kappa B activation in development and progression of cancer[J]. Cancer Sci, 2007, 98(3): 268 [3]Karin M. Nuclear factor-kappaB in cancer development and progression[J]. Nature, 2006, 441(792): 431 [4]Baldwin A S. Series introduction: the transcription factor NF-kappaB and human disease[J]. J Clin Invest, 2001, 107(1): 3 [5]O’dea E, Hoffmann A. The regulatory logic of the NF-kappaB signaling system[J]. Cold Spring Harb Perspect Biol, 2010, 2(1): a000216 [6]Oeckinghaus A, Ghosh S. The NF-kappa B Family of Transcription Factors and Its Regulation[J]. Cold Spring Harb Perspect Biol, 2009, 1(4): a000034 [7]Karin M, Greten F R. NF-kappaB: linking inflammation and immunity to cancer development and progression[J]. Nat Rev Immunol, 2005, 5(10): 749 [8]Luo J L, Kamata H, Karin M. IKK/NF-kappaB signaling: balancing Life and death--a new approach to cancer therapy[J]. J Clin Invest, 2005, 115(10): 2625 [9]Kaisho T, Takeda K, Tsujimura T, et al. IkappaB kinase alpha is essential for mature B cell development and function[J]. J Exp Med, 2001, 193(4): 417 [10]Pahl H L. Activators and target genes of Rel/NF-kappaB transcription factors[J]. Oncogene, 1999, 18(49): 6853 [11]Guttridge D C, Albanese C, Reuther J Y, et al. NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1[J]. Mol Cell Biol, 1999, 19(8): 5785 [12]王玲,单保恩,桑梅香,等.靶向沉默p65基因对人乳腺癌细胞MDA-MB-231增殖及凋亡的影响[J].南方医科大学学报,2011,31(10):1742 [13]王玲,单保恩,曹玉,等.靶向p65基因的miRNA对人三阴性乳腺癌细胞裸鼠移植瘤生长的抑制作用[J].中国癌症杂志,2012,22(2):96 [14]王玲,赵连梅,张超,等.沉默p65基因对人乳腺癌细胞MDA-MB-231细胞周期的影响[J].肿瘤防治研究,2011,38(11):1236 [15]Ito-Kureha T, Koshikawa N, Yamamoto M, et al. Tropomodulin 1 expression driven by NF-κB enhances breast cancer growth[J]. Cancer Res, 2015, 75(1): 62 [16]Ledoux A C, Sellier H, Gillies K, et al. NFκB regulates expression of Polo-like kinase 4[J]. Cell Cycle, 2013, 12(18): 3052 [17]Biswas D K, Cruz A P, Gansberger E, et al. Epidermal growth factor-induced nuclear factor kappa B activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells[J]. Proc Natl Acad Sci U S A, 2000, 97(15): 8542 [18]Handschick K, Beuerlein K, Jurida L, et al. Cyclin-dependent kinase 6 is a chromatin-bound cofactor for NF-κB-dependent gene expression[J]. Mol Cell, 2014, 53(2): 193 [19]Zhao X, Hsu K S, Lim J H, et al. Alpha actinin 4 potentiates nuclear NF-κB activity in podocytes Independent of its cytoplasmic actin binding function[J]. J Biol Chem, 2015, 290(1): 338 [20]Sen N, Paul B D, Gadalla M M, et al. Hydrogen sulfide-linked sulfhydration of NF-κB mediates its antiapoptotic actions[J]. Mol Cell, 2012, 45(1): 13 [21]Biswas D K, Shi Qian, Baily S, et al. NF-kappa B activation in human breast cancer specimens and its role in cell proliferation and apoptosis[J]. Proc Natl Acad Sci U S A, 2004, 101(27): 10137 [22]Liu R H, Liu C, Chen D Q, et al. FOXP3 controls an miR-146/NF-κB negative feedback loop that inhibits apoptosis in breast cancer cells[J]. Cancer Res, 2015, 75(8): 1703 [23]Varfolomeev E, Wayson S M, Dixit V M, et al. The inhibitor of apoptosis protein fusion c-IAP2.MALT1 stimulates NF-kappaB activation independently of TRAF1 AND TRAF2[J]. J Biol Chem, 2006, 281(39): 29022 [24]Papa S, Zazzeroni F, Pham C G, et al. Linking JNK signaling to NF-kappaB: a key to survival[J]. J Cell Sci, 2004, 117(Pt 22): 5197 [25]Wang C Y, Mayo M W, Korneluk R G, et al. NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation[J]. Science, 1998, 281(5383): 1680 [26]Li X J, Zhao Y, Zhang Y F, et al. Tumor necrosis factor α stimulates Her-2 cleavage by activated caspase-8[J]. Cell Physiol Biochem, 2012, 30(4): 889 [27]Bu Y W, Li X N, He Y C, et al. A phosphomimetic mutant of RelA/p65 at Ser536 induces apoptosis and senescence: An implication for tumor-suppressive role of Ser536 phosphorylation[J]. Int J Cancer, 2016, 138(5): 1186 [28]Xiao J S, Duan X P, Yin Q, et al. The inhibition of metastasis and growth of breast cancer by blocking the NF-κB signaling pathway using bioreducible PEI-based/p65 shRNA complex nanoparticles[J]. Biomaterials, 2013, 34(21): 5381 [29]Oh J H, Kim J H, Ahn H J, et al. Syndecan-1 enhances the endometrial cancer invasion by modulating matrix metalloproteinase-9 expression through nuclear factor kappaB[J]. Gynecol Oncol, 2009, 114(3): 509 [30]Jacob A, Jing J, Lee J, et al. Rab40b regulates trafficking of MMP2 and MMP9 during invadopodia formation and invasion of breast cancer cells[J]. J Cell Sci, 2013, 126(Pt 20): 4647 [31]杨晓文,崔明,王世清,等.乳腺癌组织核因子-κB和血管内皮生长因子表达及其临床意义[J].中华肿瘤防治杂志,2009,16(3):190, 199 [32]Storci G, Sansone P, Mari S, et al. TNFalpha up-regulates SLUG via the NF-kappaB/HIF1alpha axis, which imparts breast cancer cells with a stem cell-like phenotype[J]. J Cell Physiol, 2010, 225(3): 682 [33]Li C W, Xia W Y, Huo L F, et al. Epithelial-mesenchymal transition induced by TNF-α requires NF-κB-mediated transcriptional upregulation of Twist1[J]. Cancer Res, 2012, 72(5): 1290 [34]Paul A, Gunewardena S, Stecklein S R, et al. PKCλ/ι signaling promotes triple-negative breast cancer growth and metastasis[J]. Cell Death Differ, 2014, 21(9): 1469 [35]Malonia S K, Yadav B, Sinha S, et al. Chromatin remodeling protein SMAR1 regulates NF-κB dependent Interleukin-8 transcription in breast cancer[J]. Int J Biochem Cell Biol, 2014, 55: 220 [36]Song Z B, Ni J S, Wu P, et al. Testes-specific protease 50 promotes cell invasion and metastasis by increasing NF-kappaB-dependent matrix metalloproteinase-9 expression[J]. Cell Death Dis, 2015, 6: e1703 [37]Tafani M, Pucci B, Russo A, et al. Modulators of HIF1α and NFkB in cancer treatment: is it a rational approach for controlling malignant progression[J]. Front Pharmacol, 2013, 4: 13 [38]Lee S T, Li Zhimei, Wu Zhenlong, et al. Context-specific regulation of NF-κB target gene expression by EZH2 in breast cancers[J]. Mol Cell, 2011, 43(5): 798 [39]Pratt M A, Bishop T E, White D, et al. Estrogen withdrawal-induced NF-kappaB activity and bcl-3 expression in breast cancer cells: roles in growth and hormone independence[J]. Mol Cell Biol, 2003, 23(19): 6887 [40]Boersma M C, Dresselhaus E C, De Biase L M, et al. NF-kappaB and estrogen receptor alpha interactions:differential function in estrogen Receptor-Negative and-Positive Hormone-Independent breast cancer cells[J]. J Neurosci, 2011, 1(14): 5414 [41]Lee S H, Nam H S. TNF alpha-induced down-regulation of estrogen receptor alpha in MCF-7 breast cancer cells[J]. Mol Cells, 2008, 26(3): 285 [42]Kastrati I, Siklos M I, Calderon-Gierszal E L, et al. Dimethyl fumarate inhibits the nuclear factor κB pathway in breast cancer cells by covalent modification of p65 protein[J]. J Biol Chem, 2016, 291(7): 3639 [43]Song L Q, Liu D, Zhao Y, et al. Sinomenine inhibits breast cancer cell invasion and migration by suppressing NF-κB activation mediated by IL-4/miR-324-5p/CUEDC2 axis[J]. Biochem Biophys Res Commun, 2015, 464(3): 705 [44]Boldin M P, Baltimore D M. New effectors and regulators of NF-κB[J]. Immunol Rev, 2012, 246(1): 205
[1]赵庆庆,宋文静.NF-κB和eIF4E在子宫内膜上皮内瘤变和子宫内膜样癌中的表达及意义[J].天津医科大学学报,2016,22(06):483.
ZHAO Qing-qing,SONG Wen-jing.Expression and significance of NF-B and eIF4E in endometrial intraepithelial neoplasia and endometrioid carcinoma[J].Journal of Tianjin Medical University,2016,22(03):483.
[2]王 卓,吴洁,吕元军,等.人工发酵虫草菌粉对糖尿病大鼠肾脏IL-17、p38 MAPK和NF-κB表达的影响 [J].天津医科大学学报,2017,23(03):189.
WANG Zhuo,WU Jie,Lü Yuan-jun?,et al.Effect of artificial fermentation cordyceps powder on the expression of IL-17, p38 MAPK, NF-κB in kidneys of diabetic rats [J].Journal of Tianjin Medical University,2017,23(03):189.
[3]王金伟,张立萍,胡石甫,等.GYS1通过激活NF-κB通路促进肝细胞癌进展[J].天津医科大学学报,2024,30(05):405.[doi:10.20135/j.issn.1006-8147.2024.05.0405]
WANG Jinwei,ZHANG Liping,HU Shifu,et al.GYS1 promotes hepatocellular carcinoma progression by activating the NF-κB pathway[J].Journal of Tianjin Medical University,2024,30(03):405.[doi:10.20135/j.issn.1006-8147.2024.05.0405]