|本期目录/Table of Contents|

[1]孟宇 综述 王志强 审校.红细胞分布宽度与脓毒症相关性的研究进展[J].天津医科大学学报,2021,27(06):661-664.
点击复制

红细胞分布宽度与脓毒症相关性的研究进展(PDF)
分享到：

《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
27卷
期数:
2021年06期
页码:
661-664
栏目:
综述
出版日期:
2021-11-15

文章信息/Info

Title:
-
文章编号:
1006-8147（2021）06-0661-04
作者:
孟宇 综述 王志强 审校
（天津医科大学总医院重症医学科，天津 300052）
Author(s):
-
关键词:
红细胞分布宽度; 脓毒症; 预后
Keywords:
-
分类号:
R4
DOI:
-
文献标志码:
A
摘要:
红细胞分布宽度（RDW）是一项反映血液循环中红细胞形态大小和离散程度的指标，以往多用于不同类型的贫血诊断及鉴别诊断。近年来研究表明，RDW除用于血液系统相关疾病以外，对心血管疾病、感染性疾病、自身免疫性疾病及危重症疾病也有非常重要的临床意义。迄今为止，很多学者发现RDW对于脓毒症疾病的诊断、病情严重程度及预后评估方面均具有一定的临床价值。阐述RDW与脓毒症相关性的研究现状，有助于探索脓毒症更为便捷的预测指标，为进一步研究RDW在脓毒症中的作用机制提供思路。
Abstract:
-

参考文献/References:

[1] BATEMAN R，SHARP M，SINGER M，et al. The effect of sepsis on the erythrocyte[J]. Int J Mol Sci，2017，18（9）：1932
[2] SALVAGNO G L，SANCHIS-GOMAR F，PICANZA A，et al. Red blood cell distribution width: a simple parameter with multiple clinical applications[J]. Crit Rev Clin Lab Sci，2015，52（2）：86
[3] XANTHOPOULOS A，PAPAMICHALIS M，ZAJICHEK A，et al. In-hospital red blood cell distribution width change in patients with heart failure[J]. Eur J Heart Fail，2019，21（12）：1659
[4] SADAKA F，OBRIEN J，PRAKASH S. Red cell distribution width and outcome in patients with septic shock[J]. J Intensive Care Med，2013，28（5）：307
[5] CHEN C K，LIN S C，WU C C，et al. STARD-compliant article: the utility of red cell distribution width to predict mortality for septic patients visiting the emergency department[J]. Medicine （Baltimore)，2016，95（24）：e3692
[6] LORENTE L，MARTIN M M，ABREU-GONZALEZ P，et al. Red blood cell distribution width during the first week is associated with severity and mortality in septic patients[J]. PLoS One，2014，9（8）：e105436
[7] JIANG Y，JIANG F，KONG F，et al. Inflammatory anemia-associated parameters are related to 28-day mortality in patients with sepsis admitted to the ICU: a preliminary observational study[J]. Ann Intensive Care，2019，9（1）：67
[8] KIM C H，PARK J T，KIM E J，et al. An increase in red blood cell distribution width from baseline predicts mortality in patients with severe sepsis or septic shock[J]. Crit care，2013，17（6）：R282
[9] 朱祖芳，陆俊福，詹海超，等. 年龄对脓毒症休克患者90天全因病死率影响的回顾性队列研究[J]. 2018，13（7）：626
[10] WANG A Y，MA H P，KAO W F，et al. Red blood cell distribution width is associated with mortality in elderly patients with sepsis[J].Am J Emerg Med，2018，36（6）：949
[11] KIM S，LEE K，KIM I，et al. Red cell distribution width and early mortality in elderly patients with severe sepsis and septic shock[J]. Clin Exp Emerg Med，2015，2（3）：155
[12] JU X F，WANG F，WANG L，et al. Dynamic change of red cell distribution width levels in prediction of hospital mortality in Chinese elderly patients with septic shock[J]. Chin Med J （Engl），2017，130（10）：1189
[13] OMER I M，MOHAMMED B. A study of red cell distribution width and neonatal sepsis at Soba University Hospital，Khartoum，Sudan[J]. Sudan J Paediatr，2021，21（1）：42
[14] ELLAHONY D M，EL-MEKKAWY M S，FARAG M M. A study of red cell distribution width in neonatal sepsis[J]. Pediatr Emerg Care，2020，36（8）：378
[15] 赵育弘，张文雅，王涛，等. 降钙素原、红细胞分布宽度对早产儿败血症病情及预后评估的价值[J]. 中华围产医学杂志，2019，22（9）：641
[16] MARTIN S L，DESAI S，NANAVATI R，et al. Red cell distribution width and its association with mortality in neonatal sepsis[J]. J Matern Fetal Neonatal Med，2019，32（12）：1925
[17] PARK S H，PARK C J，LEE B R，et al. Sepsis affects most routine and cell population data （CPD) obtained using the Sysmex XN-2000 blood cell analyzer: neutrophil-related CPD NE-SFL and NE-WY provide useful information for detecting sepsis[J]. Int J Lab Hematol，2015，37（2）：190
[18] PARK H，SONG J，PARK Y，et al. Red blood cell distribution width is useful in discriminating adult onset Still′s disease and sepsis within 24 hours after hospitalization[J]. Korean J Intern Med，2018， 33（6）：1234
[19] LAUKEMANN S，KASPER N，KULKARNI P，et al. Can we reduce negative blood cultures with clinical scores and blood markers? Results from an observational cohort study[J]. Medicine（Baltimore)，2015，94（49）：e2264
[20] ZHANG H B，CHEN J，LAN Q F，et al. Diagnostic values of red cell distribution width，platelet distribution width and neutrophil-lymphocyte count ratio for sepsis[J]. Exp Ther Med，2016,12（4）：2215
[21] PURTLE S W，MOROMIZATO T，MCKANE C K，et al. The association of red cell distribution width at hospital discharge and out-of-hospital mortality following critical illness[J]. Criti Care Med，2014， 42（4）：918
[22] 龚艳，龙现明，金钧，等. 红细胞分布宽度对脓毒症预后评估的临床研究[J]. 中华危重病急救医学，2017,29（6）：481
[23] LEE C C，CHEN S Y，TSAI C L，et al. Prognostic value of mortality in emergency department sepsis score，procalcitonin，and C-reactive protein in patients with sepsis at the emergency department[J]. Shock，2008，29（3）：322
[24] F?魻RH?魪CZ Z，GOMBOS T，BORGULYA G，et al. Red cell distribution width in heart failure: prediction of clinical events and relationship with markers of ineffective erythropoiesis，inflammation，renal function，and nutritional state[J]. Am Heart J，2009,158（4）：659
[25] 安萌萌，龚平. 脓毒症相关性贫血发病机制及治疗的研究进展[J]. 中华急诊医学杂志，2018,27（10）：1175
[26] GHAFFARI S. Oxidative stress in the regulation of normal and neoplastic hematopoiesis[J]. Antioxid Redox Signal，2008,10（11）：1923
[27] RAHMAN I，ADCOCK I M. Oxidative stress and redox regulation of lung inflammation in COPD[J]. Eur Respir J，2006,28（1）：219
[28] FELKER G M，ALLEN L A，POCOCK S J，et al. Red cell distribution width as a novel prognostic marker in heart failure: data from the CHARM Program and the Duke Databank[J]. J Am Coll Cardiol，2007， 50（1）：40
[29] HU Z，SUN Y，WANG Q，et al. Red blood cell distribution width is a potential prognostic index for liver disease[J]. Clin Chem Lab Med，2013，51（7）：1403
[30] LIPPI G，TARGHER G，MONTAGNANA M，et al. Relationship between red blood cell distribution width and kidney function tests in a large cohort of unselected outpatients[J]. Scand J Clin Lab Invest，2008,68（8）：745
[31] KATO H，ISHIDA J，IMAGAWA S，et al. Enhanced erythropoiesis mediated by activation of the renin-angiotensin system via angiotensinⅡ type 1a receptor[J]. FASEB J，2005,19（14）：2023
[32] 姚波，刘大为，柴文昭，等. 脓毒症患者中红细胞分布宽度与血乳酸关系的研究[J].中国急救医学，2018，38（10）：874

相似文献/References:

[1]高秋文,谢克亮,王卫娜,等.氢气对脓毒症小鼠存活率和肝脏损伤的保护作用[J].天津医科大学学报,2013,19(06):449.
　GAO Qiu-wen,XIE Ke-liang,WANG Wei-na,et al.Protective effects of hydrogen gas on survival rate and liver injury in septic mice[J].Journal of Tianjin Medical University,2013,19(06):449.
[2]蒋森森,周长钰.平均血小板体积、红细胞分布宽度与冠心病的相关性研究[J].天津医科大学学报,2014,20(02):120.
　JIANG Sen-sen,ZHOU Chang-yu.Correlation between mean platelet volume, red blood cell distribution width and coronary heart disease [J].Journal of Tianjin Medical University,2014,20(06):120.
[3]高秋文,谢克亮,陈红光,等.Nrf2在富氢液减轻小鼠脓毒症氧化损伤中的作用[J].天津医科大学学报,2014,20(05):354.
　GAO Qiu-wen,XIE Ke-liang,CHEN Hong-guang,et al.Effect of Nrf2 in hydrogen-rich saline to reduce the oxidative damage in septic mice[J].Journal of Tianjin Medical University,2014,20(06):354.
[4]李宏亮,刘 彤,许 纲,等.红细胞分布宽度与阵发性非瓣膜性心房颤动射频消融复发的关系[J].天津医科大学学报,2016,22(02):104.
　LI Hong-liang,LIU Tong,XU Gang,et al.Association between RDW and atrial fibrillation recurrence after radiorequency catheter ablation in patients with paroxysmal non-valvular atrial fibrillation[J].Journal of Tianjin Medical University,2016,22(06):104.
[5]王彦峰,白 洁,李光明,等.血清降钙素原与肾上腺髓质素前体中段肽在婴幼儿细菌性肺炎诊疗中的临床研究[J].天津医科大学学报,2017,23(04):314.
　WANG Yan-feng,BAI Jie,LI Guang-ming,et al.Clinical research of serum procalcitonin and MR-pro-adrenomedullin in the diagnosis and treatment of bacterial pneumonia in infants[J].Journal of Tianjin Medical University,2017,23(06):314.
[6]齐 颖,陈 兵.脓毒性休克限制性液体复苏的临床研究[J].天津医科大学学报,2017,23(04):324.
　QI Ying,CHEN Bing.Clinical study on limited fluid resuscitation in septic shock[J].Journal of Tianjin Medical University,2017,23(06):324.
[7]杨蕊,许华,王兵,等.IL-18在脓毒症及脓毒症休克中预测死亡的作用[J].天津医科大学学报,2018,24(02):142.
　YANG Rui,XU Hua,WANG Bing,et al.Role of IL-18 in predicting mortality of patients with sepsis and septic shock[J].Journal of Tianjin Medical University,2018,24(06):142.
[8]杨宏伟,牛文彦.探讨uKIM-1、IL-6、T细胞亚群在脓毒症急性肾损伤中早期检测的意义[J].天津医科大学学报,2018,24(02):145.
　YANG Hong-wei,NIU Wen-yan.Value of measuring uKIM，IL-6 and T-cell subsets in sepsis patients with acute kidney injury[J].Journal of Tianjin Medical University,2018,24(06):145.
[9]黄 颖,曹 超,王 军,等.TLR4在脓毒症中对调节性T细胞功能活性的影响[J].天津医科大学学报,2018,24(06):492.
　HUANG Ying,CAO Chao,WANG Jun,et al.The effects of TLR4 on regulating the function of Tregs in sepsis[J].Journal of Tianjin Medical University,2018,24(06):492.
[10]吴 枫,李燕华,高玉雷,等.蛋白C活性联合D-二聚体在脓毒症和脓毒性休克患者病情评估中的预测价值研究[J].天津医科大学学报,2019,25(03):229.
　WU Feng,LI Yan-Hua,GAO Yu-Lei,et al.Predictive value of protein C activity combined with D-dimer in the evaluation of sepsis and septic shock[J].Journal of Tianjin Medical University,2019,25(06):229.

备注/Memo

备注/Memo:
作者简介 孟宇（1983-），女，副主任医师，硕士， 研究方向：脓毒症；通信作者：王志强， E-mail ：wzq19611231@sina.com。
更新日期/Last Update: 2021-11-15