|本期目录/Table of Contents|

[1]鞠佳君,王彦,张静,等.OSAHS患者的临床和多导睡眠图的性别差异分析[J].天津医科大学学报,2020,26(05):429-433.
　JU Jia-jun,WANG Yan,ZHANG Jing,et al.Gender differences in clinical and polysomnography in OSAHS patients[J].Journal of Tianjin Medical University,2020,26(05):429-433.
点击复制

OSAHS患者的临床和多导睡眠图的性别差异分析(PDF)
分享到：

《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
26卷
期数:
2020年05期
页码:
429-433
栏目:
临床医学
出版日期:
2020-09-20

文章信息/Info

Title:
Gender differences in clinical and polysomnography in OSAHS patients
文章编号:
1006-8147(2020)05-0429-05
作者:
鞠佳君; 王彦; 张静; 曹洁; 陈宝元
（天津医科大学总医院呼吸科，天津300052）
Author(s):
JU Jia-jun;  WANG Yan;  ZHANG Jing;  CAO Jie;  CHEN Bao-yuan
（Department of Respiratory Medicine, General Hospital, Tianjin Medical University, Tianjin 300052， China）
关键词:
睡眠呼吸暂停; 阻塞性; 性别特征; 人体测量学
Keywords:
sleep apnea;  obstructive;  gender identity;  anthropometry
分类号:
R563.9
DOI:
-
文献标志码:
A
摘要:
目的：探讨阻塞性睡眠呼吸暂停低通气综合征（OSAHS）患者的临床症状及多导睡眠图等方面的性别差异。方法：回顾性分析1 371例经整夜的多导睡眠监测(PSG)确诊为OSAHS的连续病例。比较 男性和女性OSAHS患者在人口统计学、临床症状和多导睡眠图参数的差异。结果：与男性OSAHS患者相比，女性年龄较大（P＜0.05），颈围较小（P＜0.001）。女性患者多见晨起头痛（P＜0.05）、失眠 （P＜0.001）及记忆力减退（P＜0.001）症状。不同严重程度的OSAHS患者中，女性的颈围均小于男性（P＜0.001）。不同肥胖程度的OSAHS患者中，女性的AHI小于男性（P＜0.01）。结论：与男性OSAHS 患者相比，女性患者诊断时年龄较大，颈围较大，疾病严重程度较低，缺氧程度较低，睡眠结构较好，多表现出夜尿多、失眠及记忆力减退症状。
Abstract:
Objective: To investigate the gender differences in clinical symptoms and polysomnography in patients with obstructive sleep apnea hypopnea syndrome(OSAHS). Methods: A retrospective analysis was made of 1 371 consecutive cases of OSAHS confirmed by overnight polysomnography(PSG). Differences in demographic, clinical symptoms, and polysomnography parameters between male and female OSAHS patients were compared. Results: Females were older (P<0.05) and had smaller neck circumferences (P<0.001). Female patients mainly showed symptoms of headache in the morning (P<0.05), insomnia (P<0.001) and memory loss (P<0.001). Among patients with different severity of OSAHS, the neck circumference of females was smaller than males(P<0.001). Among OSAHS patients with different degrees of obesity, females had lower AHI than males(P<0.01). Conclusion: Female patients were older at the time of diagnosis, with larger neck circumference, lower disease severity, lower hypoxia, and better sleep structure. They often showed more nocturia, insomnia and memory loss symptoms.

参考文献/References:

[1] Young T, Palta M, Dempsey J, et al. The occurrence of sleep-disordered breathing among middle-aged adults[J]. N Engl J Med, 1993, 328(17):1230
[2] Vagiakis E, Kapsimalis F, Lagogianni I, et al. Gender differences on polysomnographic findings in Greek subjects with obstructive sleep apnea syndrome[J]. Sleep Med, 2006, 7(5): 424
[3] Valipour A. Gender-related differences in the obstructive sleep apnea syndrome[J]. Pneumologie, 2012, 66(10):584
[4] Basoglu O K, Tasbakan M K. Gender differences in clinical and polysomnographic features of obstructive sleep apnea: a clinical study of 2827 patients[J]. Sleep Breath, 2018, 22(1): 241
[5] Yamakoshi S, Kasai T, Tomita Y, et al. Comparison of clinical features and polysomnographic findings between men and women with sleep apnea[J]. J Thorac Dis,2016, 8(1):145
[6] Chen N H，Johns M W，Li H Y，et al．Validation of a Chinese version of the Epworth sleepiness scale[J]. Qual Life Res, 2002, 11(8):817
[7] Liu Y, Su C, Liu R, et al. NREM-AHI greater than REM-AHI versus REM-AHI greater than NREM-AHI in patients with obstructive sleep apnea: clinical and polysomnographic features[J]. Sleep Breath, 2011, 15(3): 463
[8] Bozkurt M K, Oy A, Aydin D, et al. Gender differences in polysomnographic findings in Turkish patients with obstructive sleep apnea syndrome[J]. Eur Arch Otorhinolaryngol, 2008, 265(7): 821
[9] Walker R P, Durazo-Arvizu R, Wachter B, et al. Preoperative differences between male and female patients with sleep apnea[J]. Laryngoscope, 2001, 111(9):1501
[10] Zhang Z, Cheng J, Yang W, et al. Gender differences in clinical manifestations and polysomnographic findings in Chinese patients with obstructive sleep apnea[J]. Sleep Breath,Published online: 23 October 2019
[11] Alotair H, Bahammam A. Gender differences in Saudi patients with obstructive sleep apnea[J]. Sleep Breath, 2008, 12(4): 323
[12] Shepertycky M R, Banno K, Kryger M H. Differences between men and women in the clinical presentation of patients diagnosed with obstructive sleep apnea syndrome[J]. Sleep, 2005, 28(3): 309
[13] Quintana-Gallego E, Carmona-Bernal C, Capote F, et al. Gender differences in obstructive sleep apnea syndrome: a clinical study of 1166 patients[J]. Respir Med, 2004, 98(10): 984
[14] Franklin K A, Sahlin C, Stenlund H, et al. Sleep apnoea is a common occurrence in females[J]. Eur Respir J, 2013, 41(3): 610
[15] Alotair H, Bahammam A. Gender differences in Saudi patients with obstructive sleep apnea[J]. Sleep Breath, 2008, 12(4): 323
[16] Campos-Rodriguez F, Martinez-Garcia M A, de la Cruz-Moron I, et al. Cardiovascular mortality in women with obstructive sleep apnea with or without continuous positive airway pressure treatment: a cohort study[J]. Ann Intern Med, 2012, 156(2):115

相似文献/References:

备注/Memo

备注/Memo:
基金项目 国家自然科学基金资助（81670084，81600067， 81970084）；国家重点研发计划资助（2016YFC1304502）
作者简介 鞠佳君（1992-），女，硕士在读，研究方向：睡眠相关疾病；
通信作者：曹洁，E-mail：tjcaojie@163.com。
更新日期/Last Update: 2020-09-18