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[1]张莹华 综述,马勇杰 审校.ITSN1蛋白磷酸化的研究进展[J].天津医科大学学报,2019,25(06):666-669.
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ITSN1蛋白磷酸化的研究进展(PDF)
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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
25卷
期数:
2019年06期
页码:
666-669
栏目:
综述
出版日期:
2019-11-20

文章信息/Info

Title:
-
文章编号:
1006-8147(2019)06-0666-04
作者:
张莹华 综述; 马勇杰 审校
（天津医科大学肿瘤医院细胞生物学实验室，国家肿瘤临床医学研究中心，天津市“肿瘤防治”重点实验室，天津市恶性肿瘤临床医学研究中心，天津300060）
Author(s):
-
关键词:
ITSN1; 磷酸化; 生物学; 疾病
Keywords:
-
分类号:
Q51
DOI:
-
文献标志码:
A
摘要:
Intersectin（ITSN），又称EHSH1、Dap60和Ese-1，该基因位于人体第21号染色体上，编码一种高度保守的多结构域细胞衔接蛋白，主要调节胞吞和胞吐、肌动蛋白细胞骨架重排等生物学过程。磷酸化是蛋白质翻译后修饰的主要类型，受到蛋白激酶和磷酸酶的共同调节而保持一种动态平衡，在正常生命活动乃至肿瘤发生中发挥作用。本文总结了ITSN1磷酸化后参与的生物学过程及在一些疾病中的作用，希望能进一步了解磷酸化是如何调节ITSN1蛋白的功能。
Abstract:
-

参考文献/References:

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备注/Memo

备注/Memo:
基金项目 国家自然科学基金面上项目（81572851）
作者简介 张莹华（1990-），女，硕士在读，研究方向：生物化学与分子生物学；通信作者：马勇杰，E-mail:yongjiemagu@aliyun.com。
更新日期/Last Update: 2020-01-20