|本期目录/Table of Contents|

[1]陈伟婵,梁国聪,庞国珍,等.蛛网膜下腔出血与胃泌素-17的相关性研究[J].天津医科大学学报,2019,25(04):403-404411.
　CHEN Wei-chan,LIANG Guo-cong,PANG Guo-zhen,et al.Correlation between serum gastrin-17 and subarachnoid hemorrhage[J].Journal of Tianjin Medical University,2019,25(04):403-404411.
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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
25卷
期数:
2019年04期
页码:
403-404411
栏目:
临床医学
出版日期:
2019-07-20

文章信息/Info

Title:
Correlation between serum gastrin-17 and subarachnoid hemorrhage
文章编号:
1006-8147(2019)04-0403-02
作者:
陈伟婵1; 梁国聪2; 庞国珍1; 陈雪峰1; 陈晓驷1; 郑春霞1
（广东医科大学附属医院1.VIP病区；2.神经内科，湛江 524000）
Author(s):
CHEN Wei-chan1;  LIANG Guo-cong2;  PANG Guo-zhen1;  CHEN Xue-feng1;  CHEN Xiao-si1;  ZHENG Chun-xia1
(1.VIP Ward; 2.Department of Neurology, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524000, China)
关键词:
蛛网膜下腔出血; 胃泌素; 应激性溃疡; 幽门螺旋杆菌
Keywords:
subarachnoid hemorrhage;  gastrin;  stress ulcer;  Helicobacter pylori
分类号:
R743.34
DOI:
-
文献标志码:
A
摘要:
目的：探讨胃泌素-17（GAS-17）在蛛网膜下腔出血患者血清的表达及意义。方法：采用酶联免疫法测定了255例蛛网膜下腔出血患者、255例体检者血清的GAS-17变化。蛛网膜下腔出血同时测定幽门螺旋杆菌lgG（HP-lgG）抗体。结果：蛛网膜下腔出血组GAS-17较对照组明显增高（5.75 pmol/L vs. 2.72 pmol/L，Z =-7.110，P =0.000）。蛛网膜下腔出血组的HP-lgG抗体阳性与HP-lgG抗体阴性GAS-17含量比较差异无统计学意义（Z =-0.384，P =0.701）。结论：GAS-17升高可能参与蛛网膜下腔出血患者应激性溃疡的发生发展。
Abstract:
Objective: To investigate the expression and significance of the gastrin-17(GAS-17) content in subarachnoid hemorrhage patients. Methods: ELISA was used to measure the serum concentration of GAS-17 in 255 patients with subarachnoid hemorrhage and 255 healthy people. HP-lgG antibodies were detected in patients with subarachnoid hemorrhage. Results: For patients with subarachnoid hemorrhage, the serum GAS-17 were compared with those in the normal group, and the difference was statistically significant (5.75 pmol/L vs. 2.72 pmol/L, Z =-7.110，P =0.000). The value of GAS-17 increased significantly in patients with subarachnoid hemorrhage. In the group with subarachnoid hemorrhage, there was no significant difference between the GAS-17 content and whether the antibody of HP-lgG was positive or not(Z =-0.384，P =0.701). Conclusion: Elevated serum GAS-17 might be involved in the pathogenesis of stress ulcer of subarachnoid hemorrhage.

参考文献/References:


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备注/Memo

备注/Memo:
作者简介 陈伟婵（1987-），男，主治医师，硕士，研究方向：消化系统疾病；E-mail：383384556@qq.com。
更新日期/Last Update: 2019-08-28