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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:

21卷

期数:

2015年02期

页码:

154-157

栏目:

临床医学

出版日期:

2015-03-20

文章信息/Info

Title:

Analysis of ultrasonography and clinical pathological characteristics of follicular variant of papillary thyroid carcinoma

文章编号:

1006-8147（2015）02-0154-04

作者:

索晓鹏; 何小玲; 何向辉; 张 杰

 （天津医科大学总医院普通外科，天津300052）

Author(s):

SUO Xiao-peng; HE Xiao-ling; HE Xiang-hui; ZHANG Jie

 (Department of General Surgery, General Hospital, Tianjin Medical University ，Tianjin 300052，China)

关键词:

 ; 甲状腺乳头状癌; 滤泡亚型; 超声声像图; 临床病理特征

Keywords:

 ; papillary thyroid carcinoma; follicular variant;  ultrasonography ; clinical pathological characteristics

分类号:

R653+R445.1

DOI:

-

文献标志码:

A

摘要:

目的：分析甲状腺乳头状癌滤泡亚型临床病理特征、声像图特征。方法：回顾性分析74例甲状腺乳头状癌滤泡亚型患者（排除小于1 cm的微小癌）的临床病理和超声声像图资料。以同期甲状腺乳头状癌经典型295例、甲状腺滤泡状癌患者21例作为对照纳入本研究。结果：甲状腺乳头状癌滤泡亚型共74例，根据超声声像图不同滤泡亚型分为类经典型亚组55例（74.3%），类腺瘤样亚组19例（25.7%）。甲状腺乳头状癌滤泡亚型的淋巴结转移率较甲状腺滤泡状癌常见，但较甲状腺乳头状癌经典型少见（P<0.05）。甲状腺乳头状癌经典型、甲状腺乳头状癌滤泡亚型和甲状腺滤泡状癌的远处转移率分别为1.4%、2.7%和4.8%。两亚组肿瘤大小、多灶癌的几率、甲状腺外侵犯、淋巴结转移率及TNM分期差异有统计学意义（P<0.05）。结论：拥有超声恶性征象甲状腺乳头状癌滤泡亚型比无恶性征象的更具侵袭性，超声可以帮助预测其临床生物学表现。

Abstract:

Objective：To analyze the clinical pathological and ultrasonographic(US) features of follicular variant of papillary thyroid carcinoma(FV-PTC). Methods： Clinical pathological and ultrasonographic data of 74 FV-PTC patients （microcarcinoma less than 1 cm were excluded） were retrospectively analyzed. Two hundreds and ninty five patients with classical papillary thyroid carcinoma (C-PTCs) and 21 patients with follicular thyroid carcinoma (FTCs) were included as controls meanwhile. Results： Seventy four FV-PTC surgical cases were identified. Of the 74 FV-PTCs, 55(74.3%) were PTC-featured and 19 (25.7%) were FN-featured. Lymph-node metastases were more frequent in FV-PTC than in FTC, but significantly less common than in C-PTC (P<0.05). Distant metastasis rates were 2.7% for patients with FV-PTC, 1.4% for patients with C-PTC, and 4.8% for pateints FTC. Significant differences were found between PTC-featured and FN featured groups in tumor size, multifocality rate, Extrathyroidal extension, Lymph node metastasis and TNM staging（P<0.05）.Conclusion：FV-PTC with malignant US features seems to behave in a more aggressive fashion than FV-PTC without malignant US features. US can help predict the behavior of FV-PTC.

参考文献/References:

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备注/Memo

备注/Memo:

作者简介 索晓鹏（1986-），男，硕士在读，研究方向：普通外科；通信作者：张杰，E-mail：wxq_bf@sina.com。

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更新日期/Last Update: 2015-03-24