|本期目录/Table of Contents|

[1]杜林,陈峰,徐医军 综述,等.非编码RNA对肺癌中铁死亡调控作用的研究进展[J].天津医科大学学报,2022,28(05):568-571.
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非编码RNA对肺癌中铁死亡调控作用的研究进展(PDF)
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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
28卷
期数:
2022年05期
页码:
568-571
栏目:
综述
出版日期:
2022-09-20

文章信息/Info

Title:
-
文章编号:
1006-8147(2022)05-0568-04
作者:
杜林; 陈峰; 徐医军 综述; 张逊 审校
（天津市胸科医院胸外科，天津300222）
Author(s):
-
关键词:
肺癌; 铁死亡; 非编码RNA; 分子机制
Keywords:
-
分类号:
R34
DOI:
-
文献标志码:
A
摘要:
铁死亡是最近发现的一种新型细胞程序性死亡方式，在形态学与发生机制等方面区别于其他的细胞死亡方式。同时，非编码RNA（ncRNA）可以通过影响mRNA转录等作用调节下游靶蛋白的表达。近年来研究发现，ncRNA可以通过影响铁离子代谢、细胞脂代谢和调控谷胱甘肽过氧化物酶4（GPX4）等多种机制，参与肺癌的细胞铁死亡过程。因此，与细胞铁死亡相关的ncRNA和下游的靶基因可能成为新的肺癌临床标志物和治疗靶点。
Abstract:
-

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备注/Memo

备注/Memo:
作者简介 杜林（1988-），男，主治医师，博士在读，研究方向：肺癌基础研究；通信作者：张逊，E-mail： Zhangxun69@163.com。
更新日期/Last Update: 2022-09-20