|本期目录/Table of Contents|

[1]吴晓敏,竹丽萍,杨桐,等.双语延迟老年性痴呆发生年龄的Meta分析[J].天津医科大学学报,2021,27(02):172-175.
 WU Xiao-min,ZHU Li-ping,YANG Tong,et al.Bilingualism delays age at onset of dementia: a meta-analysis[J].Journal of Tianjin Medical University,2021,27(02):172-175.
点击复制

双语延迟老年性痴呆发生年龄的Meta分析(PDF)
分享到:

《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
27
期数:
2021年02期
页码:
172-175
栏目:
预防医学
出版日期:
2021-03-15

文章信息/Info

Title:
Bilingualism delays age at onset of dementia: a meta-analysis
文章编号:
1006-8147(2021)02-0172-04
作者:
吴晓敏竹丽萍杨桐王华楼马菲
(天津医科大学公共卫生学院流行病与卫生统计学系,天津市环境营养与人群健康重点实验室,天津300070)
Author(s):
WU Xiao-min ZHU Li-pingYANG Tong WANG Hua-louMA Fei
(Department of Epidemiology and Biostatistics, School of Public Health, Tianjin Medical University, Tianjin Key Laboratory of Environment, Nutrition and Public Health, Tianjin 300070, China)
关键词:
双语老年性痴呆预防认知储备Meta分析
Keywords:
bilingualismdementiapreventioncognitive reservemeta-analysis
分类号:
R749.1+6
DOI:
-
文献标志码:
A
摘要:
目的:探讨双语是否可以延迟老年性痴呆发生的年龄。方法:以老年性痴呆(dementia)、阿尔兹海默病(Alzheimer′s disease 或AD)、认知损伤(cognitive impairment)和双语(bilingual*)为检索词,计算机检索PubMed、EMbase、Web of Science 核心、知网、万方和维普数据库,检索时间均为建库至2019年11月20日,系统收集在此期间发表的有关双语与老年性痴呆发生年龄关系的文献,文献类型为横断面研究(现况调查)。由2名研究者独立筛选文献、提取资料并评价纳入研究的质量后,采用Stata12.0软件进行Meta分析。结果:共纳入8篇原始研究,总样本量为1 553人,单语组701人,双语组852人。Meta分析显示掌握双语的人群与仅掌握一门语言的人群相比,老年性痴呆发生年龄平均延迟4.61年(95%CI:-5.56~-3.65,P<0.05)。结论:双语可以延迟老年性痴呆发生的年龄。
Abstract:
Objective: To investigate whether bilingualism can delay age at onset of dementia with meta-analysis. Methods:Using dementia,Alzheimer′s disease,cognitive impairment and bilingual* as search terms,then PubMed,EMbase,Web of Science,CNKI,WanFang data,VIP databases were electronically searched to collect literature of the association between bilingualism and the age at onset of dementiafrom inception to Nov 20th,2019. Cross-sectional studies that aimed to investigate the relationship between bilingualism and the onset of dementia were collected.Two reviewers independently screened literature,extracted data and assessed the quality of included studies. Then,meta-analysis was performed using Stata 12.0 software. Results:A total of 8 studies involving 1 553 participates were finally included. There were 701 monolinguals and 852 bilinguals. The results of meta-analysis shows that bilingual patient′s first symptoms of dementia were,on average,4.61 years later than monolinguals(95%CI:-5.56--3.65,P<0.05). Conclusion:Bilingualism can delay the onset of dementia.

参考文献/References:

[1] Klimova B,Valis M,Kuca K. Bilingualism as a strategy to delay the onset of Alzheimer′ s disease[J]. Clin Interv Aging,2017,12:1731
[2] 晏月平,黄旭东. 努力探索应对老龄化的“中国经验”[N]. 中国人口报,2019-10-21(003)
[3] 杜娟,陈玉华,阮湘虹,等. 老年痴呆患者的精神行为状况及其影响因素[J]. 中国老年学杂志,2019,39(19):4776
[4] 柯丽,徐曼,柯攀,等. 老年痴呆患者照料负担研究进展[J]. 中国老年学杂志,2019,39(13):3310
[5] Lee A,Richards M,Chan W C,et al. Association of daily intellectual activities with lower risk of incident dementia among older Chinese adults[J]. JAMA Psychiat,2018,75(7):697
[6] Mukadam N,Sommerlad A,Livingston G. The relationship of bilingualism compared to monolingualism to the risk of cognitive decline or dementia: a systematic review and meta-analysis[J]. J Alzheimers Dis,2017,58(1):45
[7] Stern Y. Cognitive reserve in ageing and Alzheimer′s disease[J]. Lancet Neurol,2012,11(11):1006
[8] Xu H,Yang R,Qi X,et al. Association of lifespan cognitive reserve indicator with dementia risk in the presence of brain pathologies[J]. JAMA Neurol,2019,76(10):1184
[9] Mendez M F. Bilingualism and dementia: cognitive reserve to linguistic competency[J]. J Alzheimers Dis,2019,71(2):377
[10] Perani D,Abutalebi J. Bilingualism,dementia,cognitive and neural reserve[J]. Curr Opin Neurol,2015,28(6):618
[11] Zheng Y,Wu Q,Su F,et al. The protective effect of cantonese/mandarin bilingualism on the onset of Alzheimer′s disease[J]. Dement Geriatr Cogn Disord,2018,45(3/4):210
[12] Alladi S,Bak T H,Shailaja M,et al. Bilingualism delays the onset of behavioral but not aphasic forms of frontotemporal dementia[J]. Neuropsychologia,2017,99:207
[13] Alladi S,Bak T H,Duggirala V,et al. Bilingualism delays age at onset of dementia,independent of education and immigration status[J]. Neurology,2013,81(22):1938
[14] Bialystok E,Craik F,Binns M A,et al. Effects of bilingualism on the age of onset and progression of MCI and AD: evidence from executive function tests[J]. Neuropsychology,2014,28(2):290
[15] Bialystok E,Craik F I,Freedman M. Bilingualism as a protection against the onset of symptoms of dementia[J]. Neuropsychologia,2007,45(2):459
[16] Craik FIM,Bialystok E,Freedman M. Delaying the onset of Alzheimer disease Bilingualism as a form of cognitive reserve[J]. Neurology,2010,75(19):1726
[17] Clare L,Whitaker C J,Craik F I,et al. Bilingualism,executive control,and age at diagnosis among people with early-stage Alzheimer′ s disease in Wales[J]. J Neuropsychol,2016,10(2):163
[18] Schweizer T A,Ware J,Fischer C E,et al. Bilingualism as a contributor to cognitive reserve:evidence from brain atrophy in Alzheimer′s disease[J]. Cortex,2012,48(8):991
[19] 杨雪,李小波,韩婧,等. 中国健康人群中MRSA检出率的Meta分析[J]. 中国循证医学杂志,2019,19(9):1037
[20] Perani D,Farsad M,Ballarini T,et al. The impact of bilingualism on brain reserve and metabolic connectivity in Alzheimer′s dementia[J]. Proc Natl Acad Sci U S A,2017,114(7):1690
[21] Quinteros B C,Billick S B. Positive cognitive effects of bilingualism and multilingualism on cerebral function: a review[J]. Psychiatr Q,2018,89(2):273
[22] Fuller-Thomson E. Emerging evidence contradicts the hypothesis that bilingualism delays dementia onset. A commentary on "age of dementia diagnosis in community dwelling bilingual and monolingual Hispanic Americans" by Lawton et al,2015[J]. Cortex,2015, 66:170

相似文献/References:

备注/Memo

备注/Memo:
基金项目 国家自然科学基金(81874261)
作者简介 吴晓敏(1995-),女,硕士在读,研究方向:营养流行病学;通信作者:马菲,E-mail: mafei@tmu.edu.cn。
更新日期/Last Update: 2021-03-10