|本期目录/Table of Contents|

[1]王祥璞,曹雅婷,宋立婷,等.中老年牙周炎患者血脂水平与牙周指标的相关性分析[J].天津医科大学学报,2019,25(06):642-644+647.
 WANG Xiang-Pu,CAO Ya-Ting,SONG Li-Ting,et al.Correlation analysis of lipidemia level and periodontal index in middle-aged and elderlypatients with periodontitis[J].Journal of Tianjin Medical University,2019,25(06):642-644+647.
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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
25
期数:
2019年06期
页码:
642-644+647
栏目:
临床医学
出版日期:
2019-11-20

文章信息/Info

Title:
Correlation analysis of lipidemia level and periodontal index in middle-aged and elderlypatients with periodontitis
文章编号:
1006-8147(2019)06-0642-04
作者:
王祥璞曹雅婷宋立婷李佳珊邓嘉胤蒋少云
(天津医科大学口腔医院牙周科,天津 300070)
Author(s):
WANG Xiang-Pu CAO Ya-Ting SONG Li-Ting LI Jia-Shan DENG Jia-Yin JIANG Shao-Yun
(Department of Periodontology,Stomatology Hospital of Tianjin Medical University,Tianjin 300070,China)
关键词:
慢性牙周炎总胆固醇高密度脂蛋白胆固醇低密度脂蛋白胆固醇甘油三酯
Keywords:
chronic periodontitis total cholesterol high density lipoprotein cholesterol low density lipoprotein cholesterol triglyceride
分类号:
R780.1
DOI:
-
文献标志码:
A
摘要:
目的:分析中老年牙周炎患者血脂水平与牙周指标的相关性。方法:对收集的天津市某社区321例51~88岁中老年人的一般及全身状况信息进行整理,对菌斑指数(PLI)水平、BMI指数、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)和高密度脂蛋白胆固醇(HDL-C)等指标与牙周探诊深度(PD)、临床附着水平(AL)、牙龈出血指数(BI)相关性进行统计分析。结果:PLI与PD及AL显著相关(P<0.01);TC与AL显著相关(P<0.05);TC与PD、BI显著相关(P<0.01);LDL-C与BI显著相关(P<0.05);HDL-C与PD(P<0.05)和BI(P<0.01)显著相关;BMI与BI、TG、LDL-C、HDL-C显著相关(P<0.05)。结论:血脂水平与牙周临床指数之间存在相关性,可能与牙周炎的发生发展有关。
Abstract:
Objective: To investigate the relationship between lipidemia level and periodontal clinical parameters in middle-aged and elderly patients with periodontitis. Methods:The general information of 321 people(aged 51~88 years) in a certain community of Tianjin were collected. Then we analyzed the correlation among plaque index (PLI), body mass index(BMI),total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C) or high density lipoprotein cholesterol (HDL-C) and periodontal index such as periodontal depth (PD), clinical attachment level (AL), gingival bleeding index (BI). Results: PLI was significantly correlated with PD and AL (P<0.01). TC was significantly correlated with AL(P<0.05), and TG was significantly associated with PD and BI(P<0.01), while LDL-C was significantly correlated with BI (P<0.05). HDL-C was significantly correlated with PD (P<0.05) and BI(P<0.01).BMI was significantly correlated with BI, TG, LDL-C and HDL-C (P<0.05).Conclusion:Correlation between periodontal clinic index and hyperlipidemiamay contribute to the development of periodontal inflammation.

参考文献/References:

[1] Otomo-Corgel J, Pucher J J, Rethman M P, et al. State of the science: chronic periodontitis and systemic health[J]. J Evid Based Dent Pract, 2012, 12(3 Suppl): 20
[2] Jain A, Batista E J, Serhan C, et al. Role for periodontitis in the progression of lipid deposition in an animal model[J]. Infect Immun, 2003, 71(10): 6012
[3] Slocum C, Kramer C, Genco C A. Immune dysregulation mediated by the oral microbiome: potential link to chronic inflammation and atherosclerosis[J]. J Internal Med, 2016, 280(1): 114
[4] Hasturk H, Abdallah R, Kantarci A, et al. Resolvin E1 (RvE1) attenuates atherosclerotic plaque formation in diet and inflammation-induced atherogenesis[J]. Arterioscl Thromb Vasc Biol, 2015, 35(5): 1123
[5] Rydén L, Buhlin K, Ekstrand E, et al. Periodontitis increases the risk of a first myocardial infarction: a report from the PAROKRANK study[J]. Circulation, 2016, 133(6): 576
[6] Reyes L, Herrera D, Kozarov E, et al. Periodontal bacterial invasion and infection: contribution to atherosclerotic pathology[J]. J ClinPeriodontol, 2013, 40(Suppl 14): S30
[7] Leishman S J, Do H L, Ford P J. Cardiovascular disease and the role of oral bacteria[J].J Oral Microbiol, 2010, 2:5781
[8] Moeintaghavi A, Haerian-Ardakani A, Talebi-Ardakani M, et al. Hyperlipidemia in patients with periodontitis[J]. J Contemp Dent Pract, 2005, 6(3): 78
[9] Noack B, Jachmann I, Roscher S, et al. Metabolic diseases and their possible link to risk indicators of periodontitis[J]. J Periodontol, 2000, 71(6): 898
[10] 曹雅婷, 薛栋, 吴鹏, 等. 天津市部分中老年人肥胖与牙周炎症相关性的调查 [J]. 牙体牙髓牙周病学杂志, 2016, 26(3): 171
[11] Morita I, Okamoto Y, Yoshii S, et al. Five-year incidence of periodontal disease is related to body mass index[J]. J Dental Res, 2011, 90(2): 199
[12] Hertelyova Z, Salaj R, Chmelarova A, et al. The association between lipid parameters and obesity in university students [J]. J Endocrinol Invest, 2016, 39(7): 769
[13] Lgsche W 1, Marshal G J, Apatzidou D A, et al. Lipoprotein-associated phospholipase A2 and plasma lipids in patients with destructive periodontal disease[J]. J ClinPeriodontol, 2005, 32(6): 640
[14] Fentolu o, Sozen T, oz S G, et al. Short-term effects of periodontal therapy as an adjunct to anti-lipemic treatment[J]. Oral Dis, 2010, 16(7): 648
[15] Nassar P O, Walker C S, Salvador C S, et al. Lipid profile of people with diabetes mellitus type and periodontal disease[J]. Diabetes Res Clin Pract, 2012, 96(1): 35
[16] Montebugnoli L, Servidio D, Miaton R A, et al. Periodontal health improves systemic inflammatory and haemostatic status in subjects with coronary heart disease[J]. J Clin Periodontol, 2005, 32(2): 188
[17] Cutler C W, Shinedling E A, Nunn M, et al. Association between periodontitis and hyperlipidemia: cause or effect?[J]. J Periodontol, 1999, 70(12): 1429
[18] Welty F K. How do elevated triglycerides and low HDL-cholesterol affect inflammation and atherothrombosis?[J]. Curr Cardiol Rep, 2013, 15(9): 400
[19] Pirillo A, Bonacina F, Norata G D, et al. The interplay of lipids, lipoproteins, and immunity in atherosclerosis[J]. Curr Atheroscler Rep, 2018, 20(3): 12

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备注/Memo

备注/Memo:
作者简介 王祥璞(1990-),男,硕士在读,研究方向:牙周炎的发病机制研究;通信作者:邓嘉胤,E-mail: yazhou2991@126.com;蒋少云,E-mail:jiangshaoyun11@126.com。
更新日期/Last Update: 2020-01-20