|本期目录/Table of Contents|

[1]于雪迪,佘春华,孙增峰,等.婚姻状况对少突胶质细胞瘤患者预后的影响[J].天津医科大学学报,2019,25(05):488-492+495.
 YU Xue-di,SHE Chun-hua,SUN Zeng-feng,et al.Effects of marital status on patient prognosis in oligodendroglioma[J].Journal of Tianjin Medical University,2019,25(05):488-492+495.
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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
25
期数:
2019年05期
页码:
488-492+495
栏目:
临床医学
出版日期:
2019-09-20

文章信息/Info

Title:
Effects of marital status on patient prognosis in oligodendroglioma
文章编号:
1006-8147(2019)05-0488-05
作者:
于雪迪佘春华孙增峰尹 强纪昕欣马 莉李文良
(天津医科大学肿瘤医院脑系肿瘤科,国家肿瘤临床医学研究中心,天津市“肿瘤防治”重点实验室,天津市恶性肿瘤临床医学研究中心,天津300060)
Author(s):
YU Xue-di SHE Chun-hua SUN Zeng-feng YIN Qiang JI Xin-xin MA Li LI Wen-liang
(Department of Brain Oncology, Cancer Institute and Hospital, Tianjin Medical University, National Clinical Research Center for Cancer,Key Laboratoryof Cancer Prevention and Therapy, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China)
关键词:
少突胶质细胞瘤婚姻状态预后SEER规划
Keywords:
oligodendroglioma marital status prognosis SEER Program
分类号:
R739.41
DOI:
-
文献标志码:
A
摘要:
目的:探讨少突胶质细胞瘤患者婚姻状况与预后之间的关系。方法:纳入SEER数据库中自1973-2015年诊断为少突胶质细胞瘤的4 282例患者。通过Kaplan-Meier法分析患者生存率,Cox回归模型分析影响生存的独立危险因素。结果:单因素分析显示,性别、年龄、手术情况、原发灶部位、婚姻状况与少突胶质细胞瘤患者生存期相关(P<0.01)。多因素分析发现,婚姻状况是患者生存的独立预后因素(P<0.05),在相同性别、年龄范围、手术治疗情况下,丧偶仍是患者的独立危险因素(P<0.01)。结论:婚姻状况与少突胶质细胞瘤患者生存期密切相关,丧偶增加患者的死亡风险。
Abstract:
Objective: To investigate the impact of marital status on patient prognosis in oligodendroglioma. Methods:We collected 4282 eligible patients with oligodendroglioma from SEER database from 1973 to 2015. Kaplan-Meier methods were used to analyze the patients’ survival, and Cox regression models were applied to analyze independent risk factors for patients’overall survival in oligodendroglioma. Results: Univariate analysis showedthat gender, age,surgery status, and primary siteandmarital status were significantly associated with patients’ overall survival in oligodendroglioma(P <0.01). Multivariate analysis found that marital status wasthe independent prognostic factor for patients’ overall survival(P <0.05). Widowed remained the independent risk factor for patients with the same gender, age range or surgery status(P<0.01). Conclusion: Marital status might be closely associated with patients’ overall survival in oligodendroglioma, and widowed may increase the risk of death in patients.

参考文献/References:

[1] Louis D N, Perry A, Reifenberger G, et al. The 2016 world health organization classification of tumors of the central nervous system: a summary[J]. Acta Neuropathol, 2016,131(6):803
[2] Brat D J, Verhaak R G, Aldape K D, et al. Comprehensive, Integrative genomic analysis of diffuse lower-grade gliomas[J]. N Engl J Med, 2015,372(26):2481
[3] Eckel-Passow J E, Lachance D H, Molinaro A M, et al. Glioma groups based on 1p/19q, IDH, and TERT promoter mutations in tumors[J]. N Engl J Med, 2015,372(26):2499
[4] Helmer C, Damon D, Letenneur L, et al. Marital status and risk of Alzheimer’s disease: a French population-based cohort study[J]. Neurology, 1999,53(9):1953
[5] Aizer A A, Chen M H, McCarthy E P, et al. Marital status and survival in patients with cancer[J]. J Clin Oncol, 2013,31(31):3869
[6] Dupre M E, Lopes R D. Marital History and Survival After Stroke[J]. J Am Heart Assoc, 2016,5(12) :1
[7] Datta G D, Neville B A, Kawachi I, et al. Marital status and survival following bladder cancer[J]. J Epidemiol Community Health, 2009, 63(10):807
[8] Inverso G, Mahal B A, Aizer A A, et al. Marital status and head and neck cancer outcomes[J]. Cancer, 2015,121(8):1273
[9] Miao T, Li Y, Sheng X, et al. Marital status and survival of patients with kidney cancer[J]. Oncotarget, 2017,8(49): 86157
[10] Wu Y, Ai Z, Xu G. Marital status and survival in patients with non-small cell lung cancer: an analysis of 70006 patients in the SEER database[J]. Oncotarget, 2017,8(61): 103518
[11] Xie J C, Yang S, Liu X Y, et al. Marital status is associated with survival of patients with astrocytoma[J]. J Clin Neurosci, 2018,10(56):79
[12] Wang X, Li X, Su S, et al. Marital status and survival in epithelial ovarian cancer patients: a SEER-based study[J]. Oncotarget, 2017,8(51):89040
[13] Satin J R, Linden W, Phillips M J. Depression as a predictor of disease progression and mortality in cancer patients: a meta-analysis[J]. Cancer, 2009,115(22):5349
[14] Borstelmann N A, Rosenberg S M, Ruddy K J, et al. Partner support and anxiety in young women with breast cancer[J]. Psychooncology, 2015, 24(12):1679
[15] Jacob L, Bleicher L, Kostev K, et al. Prevalence of depression, anxiety and their risk factors in German women with breast cancer in general and gynecological practices[J]. J Cancer Res Clin Oncol, 2016,142(2): 447
[16] Mausbach B T, Irwin S A. Depression and healthcare service utilization in patients with cancer[J]. Psychooncology, 2017,26(8):1133
[17] Sbarra D A, Hasselmo K, Bourassa K J. Divorce and Health: Beyond Individual Differences[J]. Curr Dir Psychol Sci, 2015,24(2):109
[18] Balducci M, Fiorentino A, De Bonis P, et al. Impact of age and co-morbidities in patients with newly diagnosed glioblastoma: a pooled data analysis of three prospective mono-institutional phase II studies[J]. Med Oncol, 2012,29(5): 3478
[19] St JPD, Montgomery P R. Marital status, partner satisfaction, and depressive symptoms in older men and women[J]. Can J Psychiatry, 2009, 54(7):487
[20] Rendall M S, Weden M M, Favreault M M, et al. The protective effect of marriage for survival: a review and update[J]. Demography, 2011,48(2):481
[21] Pouratian N, Asthagiri A, Jagannathan J, et al. Surgery Insight: the role of surgery in the management of low-grade gliomas[J]. Nat Clin Pract Neurol, 2007,3(11):628
[22] Sayegh E T, Oh T, Fakurnejad S, et al. Principles of surgery for malignant astrocytomas[J]. Semin Oncol, 2014,41(4): 523

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备注/Memo

备注/Memo:
基金项目 国家自然科学基金资助项目(81702481);天津市自然科学基金资助项目(15JCQNJC44800)
作者简介 于雪迪(1992-),女,硕士在读,研究方向:颅脑肿瘤;通信作者:李文良,E-mail:Liwenliang2338@163.com。
更新日期/Last Update: 2019-10-11