|本期目录/Table of Contents|

[1]付 蔷,徐文贵,于筱舟,等.早期18F-FDG PET/CT显像在结直肠癌术后再分期中的临床价值[J].天津医科大学学报,2017,23(01):38-40.
 FU Qiang,XU Wen-gui,YU Xiao-zhou,et al.Value of early postoperative 18F-FDG PET/CT in restaging of the colorectal carcinoma[J].Journal of Tianjin Medical University,2017,23(01):38-40.
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早期18F-FDG PET/CT显像在结直肠癌术后再分期中的临床价值(PDF)
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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
23
期数:
2017年01期
页码:
38-40
栏目:
临床医学
出版日期:
2017-01-16

文章信息/Info

Title:
Value of early postoperative 18F-FDG PET/CT in restaging of the colorectal carcinoma
文章编号:
1006-8147(2017)01-0038-03
作者:
付 蔷徐文贵于筱舟刘建井李小凤
(天津医科大学肿瘤医院分子影像与核医学诊疗科,国家肿瘤临床医学研究中心;天津市“肿瘤防治”重点实验室;天津市恶性肿瘤临床医学研究中心,天津 300060)
Author(s):
FU Qiang XU Wen-gui YU Xiao-zhouLIU Jian-jingLI Xiao-feng
(Department of Molecular Imaging and Nuclear Medicine, Cancer Institute and Hospital, Tianjin Medical University , National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy ,Tianjins Clinical Research Center for China, Tianjin 300060, China)
关键词:
结直肠癌18F-FDG PET/CT显像再分期
Keywords:
colorectal carcinoma18F-FDG PET/CT restage
分类号:
R735.3
DOI:
-
文献标志码:
A
摘要:
目的:评价术后早期18F-FDG PET/CT显像在结直肠癌再分期中的临床价值。方法:回顾性分析术前分期明确后于本院行局部结直肠癌切除手术,并且行术后18F-FDG PET/CT显像的结直肠癌患者46例,根据显像结果对其进行再分期,分析分期改变率,并通过χ2检验和秩和检验分析再分期影响因素。结果:46例患者中共14例(30.4%)出现病理性18F-FDG 的摄取,其中13例证实为恶性病灶且分期上升,肝脏转移7例(53.8%),外周淋巴结转移5例(38.5%),腹膜转移1例(7.7%),意外发现其他类型肿瘤2例(15.4%),1例证实为淋巴结炎性反应性增生。PET/CT在诊断结直肠癌远处转移方面的灵敏度为100%,特异度为97.3%,阳性预测率为92.9%,阴性预测率为100%。秩和检验结果表明,相对于较早期I/II期结直肠癌病人而言,术后早期18F-FDG PET/CT显像对于晚期III期结直肠癌病人再分期改变率较高,χ2检验结果显示年龄、性别、原发部位对于术后再分期无显著影响。结论:术后早期18F-FDG PET/CT显像在结直肠癌再分期中具有重要的临床价值,尤其是对于晚期III期病人意义更为明显。
Abstract:
Objective: To evaluate 18F-FDG PET/CT in the diagnosis of restaging for colorectal carcinoma. Methods: Forty six cases, from Tumor Hospital of Tianjin Medical University, of postoperative colorectal carcinoma examined by 18F-FDG PET/CT imaging were reviewed to restage and analyze the influence factors by Chi-squared test and Kruskal-Wallis Test. Results: In all cases, pathological 18F-FDG uptake was observed in 14(30.4%). Of these,13 were upstaged with true-positive metastatic disease in distant organs after further workup liver in 7 cases, lymph node in 5 cases, peritoneum in one case) and one case had false-positive finding. The sensitivity and specificity of PET/CT for detecting metastatic disease were 100% and 97.3%, the positive predictive value was 92.9% and the negative predictive value was 100%.The Kruskal-Wallis univariate analysis showed that patients in stage III had more risk than the patients in stage I/II (P <0.05). The Chi-square test showed that age, sex and tumor location were not significantly associated with upstaging. Conclusion: The early postoperative 18F-FDG PET/CT have an important role in restaging of the colorectal carcinoma especially in the patients in stage III.

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备注/Memo

备注/Memo:

作者简介 付蔷(1991-),女,硕士在读,研究方向:肿瘤影像与核医学诊断;通信作者:徐文贵,E-mail: wenguixy@126.com。



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更新日期/Last Update: 2017-01-16