|本期目录/Table of Contents|

[1]孙秀梅,张 飞 综 述,牛瑞芳 审校. Nanog及其假基因NanogP8在肿瘤中的研究进展[J].天津医科大学学报,2015,21(01):90-封三.
点击复制

 Nanog及其假基因NanogP8在肿瘤中的研究进展(PDF)
分享到:

《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
21
期数:
2015年01期
页码:
90-封三
栏目:
综述
出版日期:
2015-01-20

文章信息/Info

Title:
-
文章编号:
1006-8147(2015)01-0090-04
作者:
孙秀梅张 飞 综 述 牛瑞芳 审校
(天津医科大学肿瘤医院公共实验室,国家肿瘤临床医学研究中心,天津市肿瘤防治重点实验室,乳腺癌防治教育部重点实验室,天津 300060)

 

Author(s):
-
关键词:
  NanogNanogP8肿瘤
Keywords:
-
分类号:
R730.2
DOI:
-
文献标志码:
A
摘要:
-
Abstract:
-

参考文献/References:

[1]Cavaleri F, Schöler H R. Nanog: a new recruit to the embryonic stem cell orchestra[J]. Cell, 2003,113(5):551

[2]Palla A R, Piazzolla D, Abad M, et al. Reprogramming activity of NANOGP8, a NANOG family member widely expressed in Cancer[J]. Oncogene, 2014,33(19):2513

[3]Poliseno L. Pseudogenes: newly discovered players in human Cancer[J]. Sci Signal, 2012,5(242):5

[4]Zhang J, Wang X, Li M, et al. NANOGP8 is a retrogene expressed in cancers[J]. FEBS J, 2006,273(8):1723

[5]Chang D F, Tsai S C, Wang X C, et al. Molecular characterization of the human NANOG protein[J]. Stem Cells, 2009,27(4):812

[6]Jeter C R, Liu B, Liu X, et al. NANOG promotes Cancer stem cell characteristics and prostate Cancer resistance to androgen deprivation[J]. Oncogene, 2011,30(36):3833

[7]Chambers I, Colby D, Robertson M, et al. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells[J]. Cell, 2003,113(5):643

[8]Jeter C R, Badeaux M, Choy G, et al. Functional evidence that the self-renewal gene NANOG regulates human tumor development[J]. Stem Cells, 2009,27(5):993

[9]Liu B, Badeaux M D, Choy G, et al. Nanog1 in NTERA-2 and recombinant NanogP8 from somatic Cancer cells adopt multiple protein conformations and migrate at multiple M.W species[J]. PLoS One, 2014,9(3):90615

[10]Fairbanks D J, Fairbanks A D, Ogden T H, et al. NANOGP8: evolution of a human-specific retro-oncogene[J]. G3 (Bethesda), 2012,2(11):1447

[11]Ambady S, Malcuit C, Kashpur O, et al. Expression of NANOG and NANOGP8 in a variety of undifferentiated and differentiated human cells[J]. Int J Dev Biol, 2010,54(11/12):1743

[12]Ishiguro T, Sato A, Ohata H, et al. Differential expression of nanog1 and nanogp8 in colon Cancer cells[J]. Biochem Biophys Res Commun, 2012,418(2):199

[13]Ibrahim E E, Babaei-Jadidi R, Saadeddin A, et al. Embryonic NANOG activity defines colorectal Cancer stem cells and modulates through AP1- and TCF-dependent mechanisms[J]. Stem Cells, 2012,30(10):2076

[14]Uchino K, Hirano G, Hirahashi M, et al. Human nanog pseudogene8 promotes the proliferation of gastrointestinal Cancer cells[J]. Exp Cell Res, 2012,318(15):1799

[15]Meng H M, Zheng P, Wang X Y, et al. Over-expression of Nanog predicts tumor progression and poor prognosis in colorectal Cancer[J]. Cancer Biol Ther, 2010,9(4):295

[16]Zhang J, Espinoza L A, Kinders R J, et al. NANOG modulates stemness in human colorectal Cancer[J]. Oncogene, 2013,32(37):4397

[17]Ezeh U I, Turek P J, Reijo R A, et al. Human embryonic stem cell genes OCT4, NANOG, STELLAR, and GDF3 are expressed in both seminoma and breast carcinoma[J]. Cancer, 2005,104(10):2255

[18]Ye F, Zhou C, Cheng Q, et al. Stem-cell-abundant proteins Nanog, Nucleostemin and Musashi1 are highly expressed in malignant cervical epithelial cells[J]. BMC Cancer, 2008,8:108

[19]Chiou S H, Wang M L, Chou Y T, et al. Coexpression of Oct4 and nanog enhances malignancy in lung adenocarcinoma by inducing Cancer stem Cell-Like properties and Epithelial-Mesenchymal transdifferentiation[J]. Cancer Res, 2010,70(24):10433

[20]Han J H, Zhang F, Yu M, et al. RNA interference-mediated silencing of NANOG reduces cell proliferation and induces G0/G1 cell cycle arrest in breast Cancer cells[J]. Cancer Lett, 2012,321(1):80

[21]Choi S C, Choi J H, Park C Y, et al. Nanog regulates molecules involved in stemness and cell cycle-signaling pathway for maintenance of pluripotency of P19 embryonal carcinoma stem cells[J]. J Cell Physiol, 2012,227(11):3678

[22]Shan J J, Shen J J, Liu L M, et al. Nanog regulates self-renewal of Cancer stem cells through the insulin-like growth factor pathway in human hepatocellular carcinoma[J]. Hepatology, 2012,56(3):1004

[23]Chiou S H, Yu C C, Huang C Y, et al. Positive correlations of Oct-4 and Nanog in oral Cancer stem-like cells and high-grade oral squamous cell carcinoma[J]. Clin Cancer Res, 2008,14(13):4085

[24]Siu M , Wong E , Kong D , et al. Stem cell transcription factor NANOG controls cell migration and invasion via dysregulation of E-cadherin and FoxJ1 and contributes to adverse clinical outcome in ovarian cancers[J]. Oncogene, 2013,32(30):3500

[25]Nagata T. Prognostic significance of NANOG and KLF4 for breast Cancer[J]. Breast Cancer, 2012,30(15, S):96

[26]Lee M, Nam E J, Kim S W, et al. Prognostic impact of the Cancer stem Cell-Related marker NANOG in ovarian serous carcinoma[J]. Int J Gynecol Cancer, 2012,22(9):1489

[27]Yang L, Zhang X, Zhang M, et al. Increased nanog expression promotes tumor development and cisplatin resistance in human esophageal Cancer cells[J]. Cell Physiol Biochem, 2012,30(4):943

[28]Zbinden M, Duquet A, Lorente-Trigos A, et al. NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53[J]. EMBO J, 2010,29(15):2659

[29]Xu F, Dai C, Zhang R, et al. Nanog: a potential biomarker for liver metastasis of colorectal Cancer[J]. Dig Dis Sci, 2012,57(9):2340

[30]He A, Qi W, Huang Y, et al. CD133 expression predicts lung metastasis and poor prognosis in osteosarcoma patients: A clinical and experimental study[J]. Exp Ther Med, 2012,4(3):435

[31]Leung E L, Fiscus R R, Tung J W, et al. Non-small cell lung Cancer cells expressing CD44 are enriched for stem cell-like properties[J]. PLoS One, 2010,5(11):14062

[32]Tsai L L, Yu C C, Chang Y C, et al. Markedly increased Oct4 and Nanog expression correlates with cisplatin resistance in oral squamous cell carcinoma[J]. J Oral Pathol Med, 2011,40(8):621

[33]Bourguignon L Y, Peyrollier K, Xia W, et al. Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells[J]. J Biol Chem, 2008,283(25):17635-17651

[34]Wang M L, Chiou S H, Wu C W. Targeting Cancer stem cells: emerging role of Nanog transcription factor[J]. Onco Targets Ther, 2013,6:1207

[35]Noh K H, Kim B W, Song K H, et al. Nanog signaling in Cancer promotes stem-like phenotype and immune evasion[J]. J Clin Invest, 2012,122(11):4077

[36]Noh K H, Lee Y H, Jeon J H, et al. Cancer vaccination drives Nanog-dependent evolution of tumor cells toward an immune-resistant and stem-like phenotype[J]. Cancer Res, 2012,72(7):1717

[37]Ma L, Zhang G, Miao X B, et al. Cancer stem-like cell properties are regulated by EGFR/AKT/β-catenin signaling and preferentially inhibited by gefitinib in nasopharyngeal carcinoma[J]. FEBS J, 2013,280(9):2027

[38]Hyder A, Ehnert S, Hinz H, et al. EGF and HB-EGF enhance the proliferation of programmable cells of monocytic origin (PCMO) through activation of MEK/ERK signaling and improve differentiation of PCMO-derived hepatocyte-like cells[J]. Cell Commun Signal, 2012,10(1):23

[39]Xu C, Xie D, Yu S C, et al. β-Catenin/POU5F1/SOX2 transcription factor complex mediates IGF-I receptor signaling and predicts poor prognosis in lung adenocarcinoma[J]. Cancer Res, 2013,73(10):3181

[40]Ho B, Olson G, Figel S, et al. Nanog increases focal adhesion kinase (FAK) promoter activity and expression and directly binds to FAK protein to be phosphorylated[J]. J Biol Chem, 2012,287(22):18656

相似文献/References:

[1]张 茜,李洪发,刘俊玲,等. 快速扩弓后牙齿及牙槽骨变化的锥体束CT研究[J].天津医科大学学报,2014,20(01):57.
 ZHANG Qian,LI Hong- fa,LIU Jun-ling,et al. Study on cone beam computed tomography study of tooth and alveolar bone changes after rapid maxillary expansion treatment [J].Journal of Tianjin Medical University,2014,20(01):57.
[2]马长辉,杨万松.血清丙氨酸转氨酶与ST段抬高型心肌梗死的相关性研究[J].天津医科大学学报,2014,20(02):116.
 MA Chang-hui,YANG Wan-song.Clinical study of serum alanine aminotransferase in patients with acute ST-segment elevation myocardial infarction[J].Journal of Tianjin Medical University,2014,20(01):116.
[3]李 颖 综述,夏 天 审校. 肥胖相关性肾病的研究进展[J].天津医科大学学报,2014,20(02):165.
[4]牛 健,于晓旭,李 雪,等.重组 CARDs TX 融合蛋白的表达纯化与复性[J].天津医科大学学报,2014,20(03):184.
 NIU Jian,YU Xiao-xu,LI Xue,et al.Expression, purification and renaturation of recombinant CARDs TX fusion protein[J].Journal of Tianjin Medical University,2014,20(01):184.
[5]陈清刚,钱 明,王 毅,等.首发精神分裂症患者与超高危人群认知功能的对照研究[J].天津医科大学学报,2014,20(03):216.
 CHEN Qing gang,QIAN Ming,WANG Yi,et al.Control study of cognitive function in ultra-high risk population of schizophrenia and first-episode schizophrenia patients[J].Journal of Tianjin Medical University,2014,20(01):216.
[6]单立新,高 越,王学菊.血清Cys C、RBP、尿mALb/ Cr检测在糖尿病肾病早期诊断中的价值[J].天津医科大学学报,2014,20(03):241.
[7]班新超,孙保存,谷彦军,等. CXCR4和CathepsinD在恶性纤维组织细胞瘤中的表达及意义[J].天津医科大学学报,2014,20(04):264.
 BAN Xin-chao,SUN Bao-cun,GU Yan-jun,et al.Expression of CXCR4 and CathepsinD in malignant fibrous histiocytoma and their biological significance[J].Journal of Tianjin Medical University,2014,20(01):264.
[8]谭艳萍,吴校伟,刘 寅,等. 冠心病合并糖尿病患者药物涂层支架术后观察[J].天津医科大学学报,2014,20(05):414.
[9]叶剑飞 综述. microRNAs与肿瘤研究的新进展[J].天津医科大学学报,2014,20(05):416.
[10]李 姗,严海泓,章 萍,等. 长春新碱致双手麻木与麻痹性肠梗阻1例报道[J].天津医科大学学报,2014,20(05):373.

备注/Memo

备注/Memo:
基金项目 国家自然科学基金资助项目(81372844; 81071731)

作者简介 孙秀梅(1985-),女,硕士在读,研究方向:生物化学与分子生物学;通信作者:牛瑞芳,E-mail:niuruifang@tjmuch.com。

更新日期/Last Update: 2015-06-11