[1] Ma H D, Wang Y H, Chang C, et al. The Intestinal Microbiota and Microenvironment in Liver [J]. Autoimmun Rev, 2015,14(3):183 [2] Oo Y H, Shetty S, Adams D H. The role of chemokines in the recruitment of lymphocytes to the liver [J]. Dig Dis, 2010, 28(1):31 [3] Palomino D C, Marti L C. Chemokines and immunity [J]. Einstein (Sao Paulo), 2015, 13(3):469 [4] Moreno C, Gustot T, Nicaise C, et al. CCR5 deficiency exacerbates T-cell-mediated hepatitis in mice [J]. Hepatology, 2005, 42(4): 854 [5] Zen Y, Liberal R, Nakanuma Y, et al. Possible involvement of CCL1-CCR8 interaction in lymphocytic recruitment in IgG4-related sclerosing cholangitis [J]. J Hepatol, 2013, 59(5):1059 [6] Béland K, Lapierre P, Djilali-Saiah I, et al. Liver restores immune homeostasis after local inflammation despite the presence of autoreactive T cells [J]. PLoS One, 2012, 7(10):e48192 [7] Saeki C, Nakano M, Takahashi H, et al. Accumulation of functional regulatory T cells in actively inflamed liver in mouse dendritic cell-based autoimmune hepatic inflammation [J]. Clin Immunol, 2010, 135(1):156 [8] Kobayashi T, Okamoto S, Iwakami Y, et al. Exclusive increase of CX3CR1+CD28- CD4+T cells in inflammatory bowel disease and their recruitment as intraepithelial lymphocytes [J]. Inflamm Bowel Dis, 2007, 13(7):837 [9] Czaja AJ. Review article: prevention and reversal of hepaticfibrosis in autoimmune hepatitis [J].Aliment Pharmacol Ther, 2014, 39(4): 385 [10] Eickmeier I, Seidel D1, Grün JR2, et al. Influence of CD8 T cell priming in liver and gut on the enterohepatic circulation [J]. J Hepatol, 2014, 60(6):1143 [11] Zhang J, Zhang W, Leung PS, et al. Ongoing activation of autoantigen-specific B cells in primary biliary cirrhosis [J]. Hepatology, 2014, 60(5):1708 [12] Landi A, Weismuller T J, Lankisch TO, et al. Differential serum levels of eosinophilic eotaxins in primary sclerosing cholangitis, primary biliary cirrhosis, and autoimmune hepatitis [J]. J Interferon Cytokine Res, 2014, 34(3):204 [13] Iwamoto S, Kido M, Aoki N, et al. TNF-α is essential in the induction of fatal autoimmune hepatitis in mice through upregulation of hepatic CCL20 expression [J]. Clin Immunol, 2013, 146(1):15 [14] Affo S, Morales-Ibanez O, RodrigoTorres D, et al. CCL20 mediates lipopolysaccharide induced liver injury and is a potential driver of inflammation andfibrosis in alcoholic hepatitis [J]. Gut, 2014, 63(11):1782 [15] Chuang YH, Lian ZX, Cheng CM, et al. Increased levels of chemokine receptor CXCR3 and chemokines IP-10 and MIG in patients with primary biliary cirrhosis and their first degree relatives [J]. J Autoimmun, 2005, 25(2):126 [16] Antonelli A, Ferrari SM, Giuggioli D, et al. Chemokine (C-X-C motif) ligand (CXCL)10 in autoimmune diseases [J]. Autoimmun Rev, 2014, 13(3):272 [17] Burak KW, Swain MG, Santodomingo-Garzon T, et al. Rituximab for the treatment of patients with autoimmune hepatitis who are refractory or intolerant to standard therapy [J]. Can J Gastroenterol, 2013, 27(5):273 [18] Ikeda A, Aoki N, Kido M, et al. Progression of autoimmune hepatitis is mediated by IL-18-producing dendritic cells and hepatic CXCL9 expression in mice [J]. Hepatology, 2014, 60(1):224 [19] Antonelli A, Fallahi P, Ferrari SM,et al. Circulating CXCL11 and CXCL10 are increased in hepatitis Cassociated cryoglobulinemia in the presence of autoimmune thyroiditis [J]. Mod Rheumatol, 2012, 22(5): 659 [20] Lee EY, Lee ZH, Song YW. CXCL10 and autoimmune diseases [J]. Autoimmun Rev, 2009, 8(5): 379 [21] Sasaki M, Miyakoshi M, Sato Y,et al. Chemokine-chemokine receptor CCL2-CCR2 and CX3CL1-CX3CR1 axis may play a role in the aggravated inflammation in primary biliary cirrhosis [J]. Dig Dis Sci, 2014, 59(2):358 [22] Manousou P, Kolios G, Drygiannakis I, et al. CXCR3 axis in patients with primary biliary cirrhosis: a possible novel mechanism of the effect of ursodeoxycholic acid [J]. Clin Exp Immunol, 2013, 172(1):9 [23] Saeki C, Nakano M, Takahashi H, et al. Accumulation of functional regulatory T cells in actively inflamed liver in mouse dendritic cell-based autoimmune hepatic inflammation [J]. Clin Immunol, 2010, 135(1): 156 [24] Zhang W, Ono Y, Miyamura Y, et al. T cell clonal expansions detected in patients with primary biliary cirrhosis express CX3CR1 [J]. J Autoimmun, 2011, 37(2):71 [25] White GE, Greaves DR. Fractalkine: a survivor’s guide: chemokines as antiapoptotic mediators [J]. Arterioscler Thromb Vasc Biol, 2012, 32(3): 589 [26] Harada K, Kakuda Y, Nakamura M, et al. Clinicopathological significance of serum fractalkine in primary biliary cirrhosis [J].Dig Dis Sci, 2013, 58(10): 3037 [27] Okamura A, Harada K, Nio M,et al.Participation of natural killer cells in the pathogenesis of bile duct lesions in biliary atresia [J]. J Clin Pathol, 2013, 66(2):99 [28] Karlmark KR, Zimmermann HW, Roderburg C, et al. The fractalkine receptor CX(3)CR1 protects against liver fibrosis by controlling differentiation and survival of infiltrating hepatic monocytes [J]. Hepatology, 2010, 52(5): 1769 [29] Wang L, Sun Y, Zhang Z, et al. CXCR5+CD4+T follicular helper cells participate in the pathogenesis of primary biliary cirrhosis [J]. Hepatology, 2015,61(2):627 [30] Maruoka R, Aoki N, Kido M, et al. Splenectomy prolongs the effects of corticosteroids in mouse models of autoimmune hepatitis [J]. Gastroenterology, 2013, 145(1):209 [31] Ahearne MJ, Allchin RL, Fox CP,et al. Follicular helper T-cells: expanding roles in T-cell lymphoma and targets for treatment [J]. Br J Haematol, 2014, 166(3): 326 [32] Tsuchiya A, Imai M, Kamimura H, et al.Increased susceptibility to severe chronic liver damage in CXCR4 conditional knock-out mice [J]. Dig Dis Sci,2012, 57(1): 2892 [33] Puchert M, Engele J. The peculiarities of the SDF-1/CXCL12 system: in some cells, CXCR4 and CXCR7 sing solos, in others, they sing duets [J].Cell Tissue Res, 2014, 355(2): 239 [34] Saiman Y, Agarwal R, Hickman DA, et al.CXCL12 induces hepatic stellate cell contraction through a calcium independent pathway [J]. Am J Physiol Gastrointest Liver Physiol, 2013, 305(5): G375 [35] Tanegashima K, Suzuki K, Nakayama Y,et al. CXCL14 is a natural inhibitor of the CXCL12-CXCR4 signaling axis [J].FEBS Lett, 2013, 587(12): 1731 [36] Costantini S, Raucci R, Colonna G, et al. Peptides targeting chemokine receptor CXCR4: structural behavior and biological binding studies [J].J Pept Sci, 2014, 20(4): 270
[1]赵小丽,高鹏,刘俊华,等.乙型病毒性肝炎患者血清炎症因子及趋化因子表达及意义[J].天津医科大学学报,2018,24(02):152.
ZHAO Xiao-li,GAO Peng,LIU Jun-hua,et al.Expression and significance of serum inflammatory cytokines and chemokines in patients with viral hepatitis B[J].Journal of Tianjin Medical University,2018,24(04):152.
[2]来佳丹,魏诗瑶,李常颖.肾癌来源的IL4I1介导Treg诱导与募集的实验研究[J].天津医科大学学报,2023,29(03):302.
LAI Jia-dan,WEI Shi-yao,LI Chang-ying.Research on inducement and recruitment of Treg mediated by IL4I1 derived from renal cell carcinoma[J].Journal of Tianjin Medical University,2023,29(04):302.
[3]李美,来佳丹,魏诗瑶,等.肾透明细胞癌来源的IL4I1介导PD1+CD8+ T淋巴细胞募集的相关研究[J].天津医科大学学报,2024,30(02):122.[doi:10.20135/j.issn.1006-8147.2024.02.0122]
LI Mei,LAI Jiadan,WEI Shiyao,et al.Research on recruitment of PD1+ CD8+ T lymphocytes mediated by IL4I1 derived from clear cell renal cell carcinoma[J].Journal of Tianjin Medical University,2024,30(04):122.[doi:10.20135/j.issn.1006-8147.2024.02.0122]
作者简介 焦国慧(1985-),主治医师,博士在读,研究方向:自身免疫性肝病;通信作者:王邦茂,E-mail:tjmedgie@yeah.net。