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[1]郭小凡 综述,邓靖宇,梁 寒 审校.PCDH10启动子甲基化与恶性肿瘤关系的研究进展[J].天津医科大学学报,2016,22(02):182-184.
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PCDH10启动子甲基化与恶性肿瘤关系的研究进展(PDF)
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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
22卷
期数:
2016年02期
页码:
182-184
栏目:
综述
出版日期:
2016-03-20

文章信息/Info

Title:
-
文章编号:
1006-8147（2016）02-0182-03
作者:
郭小凡 综述; 邓靖宇; 梁 寒 审校
（天津医科大学肿瘤医院胃部肿瘤科，国家肿瘤临床研究中心，天津市“肿瘤防治”重点实验室，天津300060）
Author(s):
-
关键词:
原钙粘蛋白细胞粘附分子; 甲基化; 肿瘤
Keywords:
-
分类号:
R73
DOI:
-
文献标志码:
A
摘要:
-
Abstract:
-

参考文献/References:

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[12]Lin Y L, Li Z G, He Z K, et al. Clinical and prognostic significance of protocadherin-10 (PCDH10) promoter methylation in bladder cancer[J].J Int Med Res,2012,40(6):2117

[13]Li Z S, Li W J, Xie J, et al. Epigenetic inactivation of PCDH10 in human prostate cancer cell lines[J].Cell Biol Int,2011,35(7):671

[14]Yu J, Cheng Y Y, Tao Q, et al. Methylation of protocadherin 10, a novel tumor suppressor, is associated with poor prognosis in patients with gastric cancer[J].Gastroenterology,2009,136(2):640

[15]Hou Y C, Deng J Y, Zhang R P, et al. Evaluating the clinical feasibility: The direct bisulfite genomic sequencing for examination of methylated status of protocadherin10 (PCDH10) promoter to predict the prognosis of gastric cancer[J].Cancer Biomark,2015,15(5):567

[16]Jao T M, Tsai M H, Lio H Y, et al. Protocadherin 10 suppresses tumorigenesis and metastasis in colorectal Cancer and its genetic loss predicts adverse prognosis[J].Int J Cancer,2014,135(11):2593

[17]Ma J G, He Z K, Ma J H, et al. Downregulation of protocadherin-10 expression correlates with malignant behaviour and poor prognosis in human bladder cancer[J].J Int Med Res,2013,41(1):38

[18]Fang S, Huang S F, Cao J, et al. Silencing of PCDH10 in hepatocellular carcinoma via de novo DNA methylation Independent of HBV infection or HBX expression[J].Clin Exp Med,2013,13(2):127

[19]Narayan G, Scotto L, Neelakantan V, et al. Protocadherin PCDH10, involved in tumor progression, is a frequent and early target of promoter hypermethylation in cervical cancer[J].Genes Chromosomes Cancer,2009,48(11):983

[20]Zhao Y, Yang Y, Trovik J, et al. A novel wnt regulatory axis in endometrioid endometrial cancer[J].Cancer Res,2014,74(18):5103

[21]Li Y, Yang Z S, Song J J, et al. Protocadherin-10 is involved in angiogenesis and methylation correlated with multiple myeloma[J].Int J Mol Med,2012,29(4):704

[22]Zhong X, Zhu Y, Mao J, et al. Frequent epigenetic silencing of PCDH10 by methylation in human colorectal cancer[J].J Cancer Res Clin Oncol,2013,139(3):485

[23]Tang X K, Yin X E, Xiang T X, et al. Protocadherin 10 is frequently downregulated by promoter methylation and functions as a tumor suppressor gene in non-small cell lung Cancer[J].Cancer Biomark, 2012,12(1):11

[24]Li Z, Yang Z, Peng X, et al. Nuclear factor-κB is involved in the protocadherin-10-mediated pro-apoptotic effect in multiple myeloma [J].Mol Med Rep,2014,10(2):832

[25]Deng J, Liang H, Ying G, et al. Clinical significance of the methylated cytosine-phosphate-guanine sites of protocadherin-10 promoter for evaluating the prognosis of gastric cancer[J].J Am Coll Surg, 2014,219(5):904

[26]Schneider B G, Mera R, Piazuelo M B, et al. DNA methylation predicts progression of human gastric lesions[J].Cancer Epidemiol Biomarkers Prev,2015,24(10):1607

[27]Wang L, Xie P G, Lin Y L, et al. Aberrant methylation of PCDH10 predicts worse biochemical recurrence-free survival in patients with prostate cancer after radical prostatectomy[J].Med Sci Monit,2014,20:1363

[28]Lin C J, Lai H C, Wang K H, et al. Testing for methylated PCDH10 or WT1 is superior to the HPV test in detecting severe neoplasms (CIN3 or greater) in the triage of ASC-US smear results[J].Am J Obstet Gynecol,2011,204(1):21

[29]Danese E, Minicozzi A M, Benati M, et al. Epigenetic alteration: new insights moving from tissue to plasma - the example of PCDH10 promoter methylation in colorectal cancer[J].Br J Cancer,2013,109(3):807

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　CHEN Sai-peng,WANG Jia-nan,WANG Lin,et al.Integrated analysis of the mechanism of methylation promoting the progress of seminomas based on the TCGA database[J].Journal of Tianjin Medical University,2019,25(02):463.
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备注/Memo

备注/Memo:
作者简介 郭小凡（1988-），女，硕士在读，研究方向：胃癌的综合治疗；通信作者：梁寒，E-mail：tjlianghan@126.com。
更新日期/Last Update: 2016-03-24