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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:

23卷

期数:

2017年02期

页码:

99-102

栏目:

专题报道

出版日期:

2017-03-20

文章信息/Info

Title:

Effect of magnetic resonance imaging scan on the?transrectal ultrasound?prostate biopsy

文章编号:

1006-8147(2017)02-0099-04

作者:

张一然; 潘盼; 连振鹏; 郑小康; 刘冉录

（天津医科大学第二医院泌尿外科，天津市泌尿外科研究所，天津300211）

Author(s):

ZHANG Yi-ran;  PAN Pan;  LIAN Zhen-peng;  ZHENG Xiao-kang;  LIU Ran-lu.

（Department of Urology, The Second Hospital,Tianjin Medical University, Tianjin Institute of Urology, Tianjin 300211, China）

关键词:

前列腺穿刺; 磁共振; 前列腺癌

Keywords:

prostatebiopsy;  magnetic resonance imaging;  prostate cancer.

分类号:

R737.25

DOI:

-

文献标志码:

A

摘要:

目的：研究前列腺穿刺前行磁共振（MRI）扫描对结果的影响，并分析其对于前列腺癌（PCa）诊断的帮助。方法：回顾性选取行经直肠超声引导前列腺穿刺的住院患者，按照穿刺前是否行MRI扫描分为两组，调查其病理结果、穿刺针数、前列腺特异性抗原（PSA）、前列腺体积（PV）等，对确诊PCa患者，统计其阳性针数占比、Gleason评分、局部侵犯神经和骨转移情况。使用统计学方法分析MRI扫描对穿刺的影响。结果：共372例患者纳入统计，其中行MRI患者255例，未行MRI患者117例。MRI组患者穿刺阳性率（52.2%vs41.0%, P=0.046）、高危患者比例（78.9%vs64.6%, P=0.049）、阳性针数占比（69.9%vs54.2%, P=0.048）均高于Non-MRI组。年龄（P=0.116）、PSA（P=0.078）、f/tPSA（P=0.329）、PV（P=0.291）、PSAD（P=0.302）之间均无组间差异，在穿刺针数（P=0.001）、阳性针数占比（P=0.039）中存在统计学差异。结论：前列腺穿刺作为PCa术前确诊最重要的技术手段，有必要在前列腺穿刺前为所有可疑患者行MRI检查，在此基础上增加穿刺针数，以获得更高的穿刺效率。

Abstract:

Objective: To investigate the effect of the magnetic resonance imaging(MRI) for prostate biopsy and analyze its assistance with the diagnosis of prostate cancer（PCa）. Methods: Patients who had undergone a transrectal ultrasound guided prostate biopsy were retrospectively included in the research. All the participants were divided into two groups according to whether or not they had a MRI scan before biopsy. The pathological results, the number of biopsy cores, the prostate specific antigen (PSA), and prostate volume (PV) of all the patients were recorded. Proportion of positive cores, Gleason scores, ECT bone scan and local neural invasion results were investigated in patients with PCa. The effect of MRI scan on biopsy was analyzed by statistical software.Results: A total of 372 patients were included in the research, including 255 patients with MRI and 117 patients without MRI. The median age was 70.5, the total positive rate was 48.7% and the high-risk patients (Gleason score over 7 points or with bone metastases or local neural invasion) accounted for 65.7% of PCa patients. The positive rate of biopsy in MRI group was higher than non-MRI group (52.2%vs41.0%, P=0.046), high-risk patients proportion in MRI group was higher than non-MRI group (69.9%vs54.2%, P=0.049), and Proportion of positive cores was significantly higher than non-MRI group (78.9%vs64.6%, P=0.048). There were no significant differences in age (P=0.116), PSA (P=0.078), f/tPSA (P=0.329), PV (P=0.291), PSAD (P=0.302) between the two groups, while the number of biopsy cores (P=0.001), proportion of positive cores (P=0.039) had significant differences between the two groups.Conclusion: Prostate biopsy may be the most important technique of PCa diagnosis. MRI scan could be necessary for all the suspectedpatients before a prostate biopsy in order to increase the number of biopsy cores and obtain higher biopsy efficiency.

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相似文献/References:

[1]张延辉,张雪君.MRI及CT诊断在颅底沟通性脑膜瘤患者中的应用对比及其预后分析[J].天津医科大学学报,2021,27(06):591.
　ZHANG Yan-hui,ZHANG Xue-jun.Comparison of MRI and CT diagnosis in patients with skull base communicating meningioma and analysis of its prognosis[J].Journal of Tianjin Medical University,2021,27(02):591.

备注/Memo

备注/Memo:

基金项目 天津市自然科学基金重点项目基金资助（15JCZDJC35900）；天津市卫生局重点攻关项目（13KG141）

作者简介 张一然（1991-），男，硕士在读，研究方向：泌尿外科；通信作者：刘冉录，E-mail:liuranlu1976@126.com。

常用功能

更新日期/Last Update: 2017-03-28