|本期目录/Table of Contents|

[1]焦国慧 综述,王邦茂,周 璐 审校.趋化因子参与自身免疫性肝病发病的研究进展[J].天津医科大学学报,2016,22(04):364-366.
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趋化因子参与自身免疫性肝病发病的研究进展(PDF)
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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
22卷
期数:
2016年04期
页码:
364-366
栏目:
综述
出版日期:
2016-07-19

文章信息/Info

Title:
-
文章编号:
1006-8147（2016）04-0364-03
作者:
焦国慧 综述;  王邦茂;  周 璐 审校
（天津医科大学总医院消化科，天津 300052）
Author(s):
-
关键词:
趋化因子; 自身免疫性肝病; 治疗
Keywords:
-
分类号:
R575
DOI:
-
文献标志码:
A
摘要:
-
Abstract:
-

参考文献/References:

[1] Ma H D, Wang Y H, Chang C, et al. The Intestinal Microbiota and Microenvironment in Liver [J]. Autoimmun Rev, 2015,14（3）:183

[2] Oo Y H, Shetty S, Adams D H. The role of chemokines in the recruitment of lymphocytes to the liver [J]. Dig Dis, 2010, 28(1):31

[3] Palomino D C, Marti L C. Chemokines and immunity [J]. Einstein (Sao Paulo), 2015, 13(3):469

[4] Moreno C, Gustot T, Nicaise C, et al. CCR5 deficiency exacerbates T-cell-mediated hepatitis in mice [J]. Hepatology, 2005, 42（4）: 854

[5] Zen Y, Liberal R, Nakanuma Y, et al. Possible involvement of CCL1-CCR8 interaction in lymphocytic recruitment in IgG4-related sclerosing cholangitis [J]. J Hepatol, 2013, 59(5):1059

[6] Béland K, Lapierre P, Djilali-Saiah I, et al. Liver restores immune homeostasis after local inflammation despite the presence of autoreactive T cells [J]. PLoS One, 2012, 7(10):e48192

[7] Saeki C, Nakano M, Takahashi H, et al. Accumulation of functional regulatory T cells in actively inflamed liver in mouse dendritic cell-based autoimmune hepatic inflammation [J]. Clin Immunol, 2010, 135(1):156

[8] Kobayashi T, Okamoto S, Iwakami Y, et al. Exclusive increase of CX3CR1+CD28- CD4+T cells in inflammatory bowel disease and their recruitment as intraepithelial lymphocytes [J]. Inflamm Bowel Dis, 2007, 13（7）:837

[9] Czaja AJ. Review article: prevention and reversal of hepaticfibrosis in autoimmune hepatitis [J].Aliment Pharmacol Ther, 2014, 39（4）: 385

[10] Eickmeier I, Seidel D1, Grün JR2, et al. Influence of CD8 T cell priming in liver and gut on the enterohepatic circulation [J]. J Hepatol, 2014, 60(6):1143

[11] Zhang J, Zhang W, Leung PS, et al. Ongoing activation of autoantigen-specific B cells in primary biliary cirrhosis [J]. Hepatology, 2014, 60(5):1708

[12] Landi A, Weismuller T J, Lankisch TO, et al. Differential serum levels of eosinophilic eotaxins in primary sclerosing cholangitis, primary biliary cirrhosis, and autoimmune hepatitis [J]. J Interferon Cytokine Res, 2014, 34(3):204

[13] Iwamoto S, Kido M, Aoki N, et al. TNF-α is essential in the induction of fatal autoimmune hepatitis in mice through upregulation of hepatic CCL20 expression [J]. Clin Immunol, 2013, 146(1):15

[14] Affo S, Morales-Ibanez O, RodrigoTorres D, et al. CCL20 mediates lipopolysaccharide induced liver injury and is a potential driver of inflammation andfibrosis in alcoholic hepatitis [J]. Gut, 2014, 63(11):1782

[15] Chuang YH, Lian ZX, Cheng CM, et al. Increased levels of chemokine receptor CXCR3 and chemokines IP-10 and MIG in patients with primary biliary cirrhosis and their first degree relatives [J]. J Autoimmun, 2005, 25（2）:126

[16] Antonelli A, Ferrari SM, Giuggioli D, et al. Chemokine (C-X-C motif) ligand (CXCL)10 in autoimmune diseases [J]. Autoimmun Rev, 2014, 13（3）:272

[17] Burak KW, Swain MG, Santodomingo-Garzon T, et al. Rituximab for the treatment of patients with autoimmune hepatitis who are refractory or intolerant to standard therapy [J]. Can J Gastroenterol, 2013, 27(5):273

[18] Ikeda A, Aoki N, Kido M, et al. Progression of autoimmune hepatitis is mediated by IL-18-producing dendritic cells and hepatic CXCL9 expression in mice [J]. Hepatology, 2014, 60(1):224

[19] Antonelli A, Fallahi P, Ferrari SM,et al. Circulating CXCL11 and CXCL10 are increased in hepatitis Cassociated cryoglobulinemia in the presence of autoimmune thyroiditis [J]. Mod Rheumatol, 2012, 22（5）: 659

[20] Lee EY, Lee ZH, Song YW. CXCL10 and autoimmune diseases [J]. Autoimmun Rev, 2009, 8（5）: 379

[21] Sasaki M, Miyakoshi M, Sato Y,et al. Chemokine-chemokine receptor CCL2-CCR2 and CX3CL1-CX3CR1 axis may play a role in the aggravated inflammation in primary biliary cirrhosis [J]. Dig Dis Sci, 2014, 59(2):358

[22] Manousou P, Kolios G, Drygiannakis I, et al. CXCR3 axis in patients with primary biliary cirrhosis: a possible novel mechanism of the effect of ursodeoxycholic acid [J]. Clin Exp Immunol, 2013, 172(1):9

[23] Saeki C, Nakano M, Takahashi H, et al. Accumulation of functional regulatory T cells in actively inflamed liver in mouse dendritic cell-based autoimmune hepatic inflammation [J]. Clin Immunol, 2010, 135（1）: 156

[24] Zhang W, Ono Y, Miyamura Y, et al. T cell clonal expansions detected in patients with primary biliary cirrhosis express CX3CR1 [J]. J Autoimmun, 2011, 37(2):71

[25] White GE, Greaves DR. Fractalkine: a survivor’s guide: chemokines as antiapoptotic mediators [J]. Arterioscler Thromb Vasc Biol, 2012, 32（3）: 589

[26] Harada K, Kakuda Y, Nakamura M, et al. Clinicopathological significance of serum fractalkine in primary biliary cirrhosis [J].Dig Dis Sci, 2013, 58（10）: 3037

[27] Okamura A, Harada K, Nio M,et al.Participation of natural killer cells in the pathogenesis of bile duct lesions in biliary atresia [J]. J Clin Pathol, 2013, 66（2）:99

[28] Karlmark KR, Zimmermann HW, Roderburg C, et al. The fractalkine receptor CX(3)CR1 protects against liver fibrosis by controlling differentiation and survival of infiltrating hepatic monocytes [J]. Hepatology, 2010, 52（5）: 1769

[29] Wang L, Sun Y, Zhang Z, et al. CXCR5+CD4+T follicular helper cells participate in the pathogenesis of primary biliary cirrhosis [J]. Hepatology, 2015,61（2）：627

[30] Maruoka R, Aoki N, Kido M, et al. Splenectomy prolongs the effects of corticosteroids in mouse models of autoimmune hepatitis [J]. Gastroenterology, 2013, 145(1):209

[31] Ahearne MJ, Allchin RL, Fox CP,et al. Follicular helper T-cells: expanding roles in T-cell lymphoma and targets for treatment [J]. Br J Haematol, 2014, 166(3): 326

[32] Tsuchiya A, Imai M, Kamimura H, et al.Increased susceptibility to severe chronic liver damage in CXCR4 conditional knock-out mice [J]. Dig Dis Sci,2012, 57（1）: 2892

[33] Puchert M, Engele J. The peculiarities of the SDF-1/CXCL12 system: in some cells, CXCR4 and CXCR7 sing solos, in others, they sing duets [J].Cell Tissue Res, 2014, 355（2）: 239

[34] Saiman Y, Agarwal R, Hickman DA, et al.CXCL12 induces hepatic stellate cell contraction through a calcium independent pathway [J]. Am J Physiol Gastrointest Liver Physiol, 2013, 305（5）: G375

[35] Tanegashima K, Suzuki K, Nakayama Y,et al. CXCL14 is a natural inhibitor of the CXCL12-CXCR4 signaling axis [J].FEBS Lett, 2013, 587（12）: 1731

[36] Costantini S, Raucci R, Colonna G, et al. Peptides targeting chemokine receptor CXCR4: structural behavior and biological binding studies [J].J Pept Sci, 2014, 20（4）: 270

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备注/Memo

备注/Memo:
基金项目 国家自然科学基金资助项目（ 81470834）；天津医科大学总医院青年孵育基金资助项目（ZYYFY2014008）

作者简介 焦国慧（1985-），主治医师，博士在读，研究方向：自身免疫性肝病；通信作者：王邦茂，E-mail：tjmedgie@yeah.net。

更新日期/Last Update: 2016-07-13