子查询返回的值不止一个。当子查询跟随在 =、!=、<、<=、>、>= 之后，或子查询用作表达式时，这种情况是不允许的。 NFAT2在非小细胞肺癌中的表达及预后关联研究-《天津医科大学学报》
|本期目录/Table of Contents|

[1]李晶鑫,许芳秀,王玉,等.NFAT2在非小细胞肺癌中的表达及预后关联研究[J].天津医科大学学报,2016,22(05):417-420.
　LI Jing-xin,XU Fang-xiu,WANG Yu,et al.Relationship between expression of NFAT2 and survival prognosis in? non-small cell lung cancer[J].Journal of Tianjin Medical University,2016,22(05):417-420.
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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
22卷
期数:
2016年05期
页码:
417-420
栏目:
临床医学
出版日期:
2016-09-20

文章信息/Info

Title:
Relationship between expression of NFAT2 and survival prognosis in? non-small cell lung cancer
文章编号:
1006-8147（2016）05-0417-4
作者:
李晶鑫1; 许芳秀1; 2; 王玉1; 郭燕1; 3; 钱碧云1; 4
（1.天津医科大学肿瘤医院肿瘤流行病与生物统计室，国家肿瘤临床医学研究中心，天津市“肿瘤防治”重点实验室，天津300060；2.解放军第401 医院药剂科，青岛266071；3.天津医科大学肿瘤医院病理科，天津300060；4.上海交通大学公共卫生学院，上海200025）
Author(s):
LI Jing-xin1; XU Fang-xiu1; 2; WANG Yu1; GUO Yan1; 3; QIAN Bi-yun1; 4
关键词:
NFAT2; 非小细胞肺癌; 免疫组织化学技术
Keywords:
NFAT2;  non-small cell lung cancer;  immunohistochemistry
分类号:
R730.2
DOI:
-
文献标志码:
A
摘要:
目的：研究NFAT2在非小细胞肺癌（NSCLC）中的表达情况及与患者生存预后的关系。方法：收集原发性NSCLC肿瘤组织315例及其配对的正常组织164例，免疫组织化学染色检测NFAT2蛋白表达情况，同时进行临床关联及预后分析。结果：NFAT2在NSCLC中高表达（P<0.001）。在女性及非吸烟早期NSCLC中，NFAT2表达上调与生存期缩短相关，差异具有统计学意义（P=0.003、P=0.001）。结论：NFAT2是NSCLC发生的危险因子，NFAT2高表达可能预示着不良预后结局。
Abstract:
Objective: To study the relationship between the NFAT2 expression in non-small cell lung cancer (NSCLC) and the survival prognosis in NFAT2 and NSCLC. Methods: NFAT2 expression were detected by applying Immunohistochemistry in 315 NSCLC cancer tissues and 164 adjacent normal tissues. Then， the relationship between NFAT2 expression and survival prognosis was studied in NSCLC. Results: NFAT2 increased in NSCLC tumor tissues (P<0.001). The subgroup analysis showed that in the early NSCLC women and non-smokers, NFAT2 expression was significantly correlated with shortened survival (P=0.003, P=0.001). Conclusion: NFAT2 is a risk factor for NSCLC. NFAT2 high expression may indicate poor prognosis.

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备注/Memo

备注/Memo:
基金项目国家自然科学基金资助项目（81573231）；天津市自然科学基金资助项目（13JCYBJC23100）

作者简介 李晶鑫（1988-），女，硕士在读，研究方向：肺癌病因学及分子流行病学；通信作者：钱碧云，E-mail：qianbiyun@126.com。

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更新日期/Last Update: 2016-09-20