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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:

22卷

期数:

2016年01期

页码:

47-50

栏目:

临床医学

出版日期:

2016-01-20

文章信息/Info

Title:

-

文章编号:

1006-8147（2016）01-0047-04

作者:

?梁家正; 李黎明; 汤坤龙; 刘晓龙; 朱国栋

（天津医科大学总医院泌尿外科，天津 300052)

Author(s):

-

关键词:

原发性醛固酮增多症;  高血压;  低血钾; 醛固酮肾素活性比值

Keywords:

-

分类号:

R586.2+4

DOI:

-

文献标志码:

A

摘要:

目的： 分析经病理证实的原发性醛固酮增多症（PHA）患者的临床特点。方法：对2012年5月至2015年3月间连续确诊的143例PHA患者的临床资料进行回顾性分析。结果：血压升高者135例，其中1、2、3级高血压分别占1.39%、28.67%、64.34%。低血钾者占105例。醛固酮和肾素活性比值(ARR)≥40者占75.52%，ARR≥40且肾素活性减低者占24.48%，ARR≥40且醛固酮浓度升高者占44.76%，醛固酮浓度升高且肾素活性降低者占12.59%，醛固酮浓度升高者占61.54%，肾素活性降低者占24.48%。B超、CT及MRI检查肾上腺病变阳性率分别为60.87%,100%,90.91%。CT和MRI对PHA的检出率高于超声（P＜0.01）。CT对醛固酮腺瘤和皮质增生的诊断符合率分别为92.22%和55%（P＜0.01），MRI对醛固酮腺瘤和皮质增生的诊断符合率分别为80%和100%（P＞0.05）。结论：PHA主要表现为中重度高血压，血钾正常者不能排除PHA的诊断。ARR≥40作为切点对诊断PHA具有较高的敏感性，可能有助于减少漏诊率。CT对PHA有较高的检出率和诊断符合率。

Abstract:

-

参考文献/References:

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