|本期目录/Table of Contents|

[1]杨 虹,田凤石.颈动脉内中膜厚度与H型高血压及相关因素的分析[J].天津医科大学学报,2014,20(02):137-139.
　YANG Hong,TIAN Feng-Shi.Analysis of carotid intima-media thickness , H type of hypertension and related factors[J].Journal of Tianjin Medical University,2014,20(02):137-139.
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颈动脉内中膜厚度与H型高血压及相关因素的分析(PDF)
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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
20卷
期数:
2014年02期
页码:
137-139
栏目:
临床医学
出版日期:
2014-03-20

文章信息/Info

Title:
Analysis of carotid intima-media thickness , H type of hypertension and related factors
文章编号:
1006-8147(2014)02-0137-03
作者:
杨 虹1; 2 ; 田凤石3
(1.天津医科大学研究生院，天津300070；2.天津市公安医院物检科，天津 300042；3.天津市第四中心医院心内科，天津 300140)
Author(s):
YANG Hong1; 2 ;  TIAN Feng-Shi3
(1.Graduate School, Tianjin Medical University, Tianjin 300070，China;2. Department of Physical Inspection, Tianjin Gongan Hospital, Tianjin 300042, China, 3. Department of Cardiology, Tianjin Fourth Center Hospital, Tianjin 300140, China)
关键词:

“H型”高血压; 超声; 颈动脉内中膜厚度; 颈动脉斑块

Keywords:
H-typehypertension;  ultrasound;  ;  carotid intima-media thickne;  ;  atherosclerosis
分类号:
R544.1
DOI:
-
文献标志码:
A
摘要:

目的：探讨颈动脉内中膜厚度与H型高血压及相关因素的关系。方法：选取244例高血压患者,根据同型半胱氨酸(Hcy)水平分为H型高血压组(Hcy≥10μmol/L)、非H型高血压组(Hcy<10 μmol/L)，测量颈动脉内中膜厚度(IMT),观察有无斑块、斑块位置及类型,计算斑块积分并测量血甘油三酯(TG)、胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)等指标;同时收集年龄、性别、病程等流行病学资料。结果：H型高血压组颈动脉IMT、斑块积分、斑块检出率、合并脑梗死及冠心病构成比均高于非H型高血压组,两组间差异有统计学意义(P<0.05)。相关分析显示：颈动脉IMT与Hcy、FBG、HDL-C、年龄及高血压病程有相关性。结论：H型高血压与颈动脉内中膜厚度密切相关，HHcy可在高血压的基础上加速动脉硬化的进程。

Abstract:
  Objective: To investigate the relationship of carotid intima-media thickness (IMT) and H-type hypertension as well as its relevant factors. Methods: According to their levels of Hcy, 244 patients were divided into two groups: the H-type hypertension group (Hcy≥10 μmo/L) and non-H-type hypertension group (Hcy< 10 μmol/L). Carotid intima-media thickness was measured and the location and type of plaque were observed. Meanwhile, the plaque integral was calculated and the blood triglycerides, cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and other indicators were all measured epidemiological data such as age, gender, duration were collected. Results: In the H-type hypertension group, the factor values of IMT, piaque score, plaque detection rate, merging, cerebral infarction and coronary heart disease were higher than those in non-hypertension group（P<0.05）. Analysis showed that IMT was correlated with Hcy and FBG, HDL-C, age as well as hypertension duration. Conclusion: The high incidence of H-type hypertension is related to IMT. HHcy can accelerate the process of arteriosclerosis in the condition of hypertension.

参考文献/References:

[1] Saceo R L，Adams R，Albers G, et a1 Guidelines for prevention of stroke in patients with is chemic stroke or transient is chemic attack：astatement for health are professionals from the American Heart Assoeiation／American Stroke Association Council on Stroke：cosponsored by the Council on Cardiovascular Radiology and Intervention：the American A cademy of Neurology affirms the value of this guideline[J]．Circulation，2006，113 (10)：409

[2] 张琛涛，新玲．H型高血压的研究进展[J]．中国医药指南，201l，9(26)：202

[3] Finn A V，Kolodgie F D，Virmani R．Correlation between carotid intimal／medial thickness and atherosclerosis a point of view from pathology[J]．Arterioseler Thromb Vase Biol，2010,30(2)：177

[4] 中国高血压防治指南修订委员会．中国高血压防治指南 2010[J]．中国高血压杂志，2011，19(8)：709

[5] 中华医学会神经病分会脑血管病学组．中国急性缺血性脑卒中诊治指南 2010[J]．中华神经科杂志，2010，43(2)：2

[6] 叶任高, 陆再英. 内科学[M]. 北京: 人民卫生出版社, 2005:250-263

[7] Rahimtoola SH．The year in valvular heart disease[J]．J Am Coll Cardiol，2011，58(12)：1197

[8] 吴凤芸，张宇虹，苏本利．高频超声评价2型糖尿病患者颈动脉粥样硬化血管重构[J]．中国医学影像技术，2009，25(1)：65

[9] 李建华，杨文东，王其国．血清氧化型低密度脂蛋白及同型半胱氨酸水平与冠状动脉病变严重程度的相关性研究[J]．实用心脑肺血管病杂志，2012，20(2)：227

[10] Goldstein L B，Bushnell C D，Adams R J，et a1．Guidelines for the primary prevention of stroke：A guideline for healtheare professionals from the American heart association／American stroke association [J]．Stroke，2011，42(2)：517

[11] Bauer M，Caviezel S，Teynor A，et a1．Carotid intima-media thickness as a biomarker of subclinical atheroselerosis[J]．Swiss Med Wkly，2012，142(4)：3705

[12] Umeh E O，Aqunloye A M，Adekanmi A J，et a1．Ultrasound evaluation of intima-media thickness of carotid arteries in adults with primary hypertension at Ibadan，Nigeria[J]．West Afr J Med，2013，32(1)：62

[13] 赵锋，李建平，王淑玉，等．高血压人群基线同型半胱氨酸水平对依那普利叶酸降压及降同型半胱氨酸疗效的分析[J] 中华医学杂志，2008，88(5)：2957

[14] Sen U，Mishra P K，Tyasi N，et a1．Homocysteine to hydrogen sulfide or hypertension[J]．Cell Biochem Biophys，2010，57(3)：49

[15] 黄中红,苏莉莉.176例颈动脉内膜增厚病变的超声分析[J].现代中西医结合杂志,2010，19(22):2820

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备注/Memo

备注/Memo:
作者简介 杨虹（1979-），女，硕士在读，研究方向：心血管病；
通信作者：田凤石，E-mail：fengshitian0801@hotmail.com。
更新日期/Last Update: 2014-03-31