|本期目录/Table of Contents|

[1]付怡如 时倩倩 综述 付 丽 审校.乙醛脱氢酶2型与肿瘤相关性的研究进展[J].天津医科大学学报,2022,28(02):214-217.
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乙醛脱氢酶2型与肿瘤相关性的研究进展(PDF)
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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
28卷
期数:
2022年02期
页码:
214-217
栏目:
综述
出版日期:
2022-03-20

文章信息/Info

Title:
-
文章编号:
1006-8147(2022)02-0214-04
作者:
付怡如 时倩倩 综述 付 丽 审校
（天津医科大学肿瘤医院乳腺病理科，国家肿瘤临床医学研究中心，天津市“肿瘤防治”重点实验室，天津市恶性肿瘤临床医学研究中心，乳腺癌防治教育部重点实验室，天津300060）
Author(s):
-
关键词:
乙醛脱氢酶2型; 氧化代谢; 肿瘤
Keywords:
-
分类号:
R73
DOI:
-
文献标志码:
A
摘要:
乙醛脱氢酶2型(ALDH2)是乙醇氧化代谢过程中的关键酶，主要功能是将乙醛(ACE)代谢成无毒的乙酸。近年的研究表明，ALDH2基因多态性增加肿瘤的易感性，该酶的相关突变所致活性降低或失活导致ACE蓄积，进而影响遗传物质的复制及促进氧化应激，从而参与肿瘤的发生及侵袭、转移。此外ALDH2的表达水平也与肿瘤患者的预后相关。现就ALDH2的结构、功能及其肿瘤相关性研究进行综述。
Abstract:
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相似文献/References:

备注/Memo

备注/Memo:
基金项目 国家自然科学基金(81672637,81872164)
作者简介 付怡如（1995-），女，硕士在读，研究方向：乳腺浸润性微乳头状癌；通信作者：付丽，E-mail：fulijyb@hotmail.com。
更新日期/Last Update: 2022-03-20