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[1]魏丽坤,宋学茹,赵明飞,等.辅助生殖技术单胎妊娠女性围产结局分析[J].天津医科大学学报,2020,26(06):530-532,537.
　WEI Li-kun,SONG Xue-ru,ZHAO Ming-fei,et al.Analysis of perinatal outcomes in assisted reproductive technology singletons[J].Journal of Tianjin Medical University,2020,26(06):530-532,537.
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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
26卷
期数:
2020年06期
页码:
530-532,537
栏目:
临床医学
出版日期:
2020-11-20

文章信息/Info

Title:
Analysis of perinatal outcomes in assisted reproductive technology singletons
作者:
魏丽坤1; 宋学茹1; 赵明飞1; 王崇丹2; 徐铮3; 丁洁4; 薛凤霞1
1.天津医科大学总医院妇产科，天津300052；2.天津市滨海新区塘沽妇产医院妇产科，天津 300451；3.天津市红桥 医院妇产科，天津 300131；4.天津市北辰区中医医院妇产科，天津300400
Author(s):
WEI Li-kun1;  SONG Xue-ru1;  ZHAO Ming-fei1;  WANG Chong-dan2;  XU Zheng3;  DING Jie4;  XUE Feng-xia1
1.Department of Gynecology and Obstetrics, General Hospital，Tianjin Medical University，Tianjin 300052，China；2. Department of Gynecology and Obstetrics, Tanggu Maternity Hospital，Tianjin Binhai New District, Tianjin 300451, China；3. Department of Gynecology and Obstetrics, Tianjin Red Bridge Hospital, Tianjin 300131, China；4. Department of Gynecology and Obstetrics, Tianjin Beichen Chinese Medicine Hospital, Tianjin 300400, China
关键词:
辅助生殖技术; 围产结局; 妊娠期糖尿病; 前置胎盘; 早产
Keywords:
assisted reproductive technology; perinatal outcomes; gestational diabetes mellitus;  placenta previa; premature delivery
分类号:
R711.6
DOI:
-
文献标志码:
A
摘要:
目的：分析辅助生殖技术（ART）单胎妊娠女性围产期母婴结局与自然妊娠女性的差异。方法：回顾性分析了 234例ART单胎妊娠女性（ART组）和20 906名自然妊娠单胎女性（自然妊娠组）围产期妊娠结局，分别比较两组间母婴 围产期并发症差异，包括妊娠期高血压疾病、妊娠期糖尿病（GDM）、前置胎盘、早产、产后出血、分娩方式等，新生 儿结局如新生儿平均出生体重、新生儿窒息、低出生体重儿及巨大儿的发生率、新生儿转入新生儿重症监护病房 （NICU）的发生率及新生儿出生性别比。结果：ART组较自然妊娠组GDM（χ２=67.978，P=0.000）、前置胎盘（χ２ =27.565，P=0.000）、早产（χ２=11.874，P=0.001）、剖宫产分娩（χ２=92.042，P=0.000）的发生风险均显著增 加。ART组较自然妊娠组低出生体重儿（χ２=13.534，P=0.000）、巨大儿（χ２=8.328，P=0.004）、新生儿转入 NICU（χ２=5.763，P=0.016）的发生风险均显著增加。结论：与自然妊娠女性相比，ART单胎妊娠女性母婴不良围产 结局显著增加。
Abstract:
Objective: To analyze the perinatal outcomes of assisted reproductive technology（ART） singleton pregnancies in comparison to spontaneously conceived singletons. Methods: Perinatal outcomes of 234 ART singletons（ART group） and 20 906 spontaneous pregnancies （spontaneous pregnancy group） were analyzed retrospectively. Perinatal complications such as hypertensive disorders complicating pregnancy（HDCP），gestational diabetes mellitus（GDM），placenta previa，premature delivery， postpartum hemorrhage，mode of delivery and neonatal outcomes such as neonatal average birth weight, the incidence of the neonatal asphyxia，low birth weight infants，macrosomia， and neonatal transfer to NICU and neonatal sex ratio were compared between the two groups. Results: ART group had higher GDM（χ ２=67.978, P=0.000），placenta previa（χ２=27.565, P=0.000）, premature delivery（χ２=11.874, P=0.001 ） and cesarean delivery rate（χ２=92.042, P=0.000） than spontaneous pregnancy group. ART group had higher low birth weight infants（χ２=13.534, P=0.000），macrosomia（χ２=8.328, P=0.004） and neonatal transfer to NICU rate（χ２=5.763, P=0.016） than spontaneous pregnancy group. Conclusion: Compared with spontaneous pregnancy group, ART singleton pregnancies increased the risks of adverse perinatal outcomes.

参考文献/References:

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备注/Memo

备注/Memo:
文章编号 1006-8147（2020）06-0530-03
基金项目 天津医科大学科学基金（2016KYZM13）
作者简介 魏丽坤（1979-），女，主治医师，博士，研究方向：生殖医学；通信作者：薛凤霞，E-mail： fengxiaxue1962＠163.com。
更新日期/Last Update: 2020-11-20