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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:

26卷

期数:

2020年04期

页码:

358-361

栏目:

临床医学

出版日期:

2020-07-15

文章信息/Info

Title:

Efficacy of combined use of T2WI, DWI and DCE-MRI in the diagnosis of prostate cancer

文章编号:

1006-8147(2020)04-0358-04

作者:

黄晓莹¹; 胡亚萍¹; 张婷玉¹; 徐卫波²

（1.开封市人民医院影像科，开封475000 ；2.河南大学淮河医院医学影像科，开封475000）

Author(s):

HUANG Xiao-ying¹;  HU Ya-ping¹;  ZHANG Ting-yu¹;  XU Wei-bo²

（1. Department of Imaging, Kaifeng People′s Hospital, Kaifeng 475000, China; 2. Department of Medical Imaging, Huaihe Hospital, Henan University, Kaifeng 475000, China)

关键词:

T2加权成像; 扩散加权成像; 动态对比增强磁共振成像; 前列腺癌

Keywords:

T2-weighted imaging;  diffusion-weighted imaging;  dynamic contrast-enhanced magnetic resonance imaging;  prostate cancer

分类号:

R445.2

DOI:

-

文献标志码:

A

摘要:

目的：探讨T2加权成像（T2WI）、扩散加权成像（DWI）及动态对比增强磁共振成像（DCE-MRI）联合诊断前列腺癌的价值。方法：选取2017年3月—2019年4月就诊的疑似前列腺癌患者119例，均行常规MRI、DWI和DCE-MRI检查。结果：119例疑似患者中，有69例诊断为前列腺癌，有50例诊断为前列腺增生；T2WI、DWI和DCE-MRI联合诊断前列腺癌的灵敏性为97.10%，明显高于T2WI、DWI单独诊断（均P＜0.05）；T2WI、DWI、DCE-MRI及联合诊断前列腺癌特异性、准确率比较差异无统计学意义（均P＞0.05）；前列腺癌Ktrans、KeP、Ve和VP分别为（1.42±0.87）、（1.83±0.80）、（0.84±0.21）和（0.15±0.07），明显高于前列腺增生（均P＜0.05），而ADC为（0.92±0.34）×10-3 mm2/s，明显低于前列腺增生（P＜0.05）；Ktrans、KeP、Ve、VP与Gleason评分无相关性（均P＞0.05），ADC值与Gleason评分呈负相关（r=-0.508，P＜0.05）。结论：T2WI、DWI及DCE-MRI联合用于诊断前列腺癌有较好的效果，其中DWI及DCE-MRI可为诊断提供客观参数。

Abstract:

Objective: To explore the value of combined use of T2-weighted imaging(T2WI), diffusion-weighted imaging(DWI) and dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI) in the diagnosis of prostate cancer. Methods: 119 patients with suspected prostate cancer were selected from March 2017 to April 2019, and the routine MRI, DWI and DCE-MRI were performed. Results: Of 119 suspected cases, 69 were diagnosed as prostate cancer and 50 were diagnosed as benign prostatic hyperplasia. The sensitivity of combined diagnosis of T2WI, DWI and DCE-MRI for prostate cancer was 97.10%, which were significantly higher than that of single diagnosis of T2WI and DWI (all P< 0.05). There were no significant difference in specificity and accuracy of T2WI, DWI, DCE-MRI and combined diagnosis of prostate cancer (all P> 0.05). Ktrans, KeP, Ve and VP of prostate cancer were (1.42±0.87), (1.83±0.80), (0.84±0.21) and (0.15±0.07) respectively, which were significantly higher than those of benign prostatic hyperplasia (all P<0.05), while ADC was (0.92±0.34)×10-3 mm2/s, which was significantly lower than that of benign prostatic hyperplasia(P< 0.05). Ktrans, KeP, Ve and VP were not correlated with Gleason score(all P>0.05), but ADC was negatively correlated with Gleason score(r=-0.508, P<0.05). Conclusion: The combination of T2WI, DWI and DCE-MRI has a good effect in the diagnosis of prostate cancer, and DWI and DCE-MRI can provide objective parameters for the diagnosis.

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备注/Memo

备注/Memo:

基金项目 河南省科技发展计划项目（192102310109）
作者简介 黄晓莹（1987-），女，主治医师，学士， 研究方向：医学影像诊断；E-mail ： abc32165897@163.com。

常用功能

更新日期/Last Update: 2020-07-15