|本期目录/Table of Contents|

[1]朱婷婷 综述,周旋 审校.ZIP4与肿瘤生物学行为的研究进展[J].天津医科大学学报,2020,26(02):183-187.
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ZIP4与肿瘤生物学行为的研究进展(PDF)
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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
26卷
期数:
2020年02期
页码:
183-187
栏目:
综述
出版日期:
2020-04-30

文章信息/Info

Title:
-
文章编号:
1006-8147(2020)02-0188-05
作者:
朱婷婷 综述周旋 审校
(天津医科大学肿瘤医院颌面和耳鼻喉肿瘤科,国家肿瘤临床医学研究中心,天津市“肿瘤防治”重点实验室,天津市恶性肿瘤临床医学研究中心,天津 300060)
Author(s):
-
关键词:
上皮间质转化锌离子转运蛋白ZIP4肿瘤发生转移
Keywords:
-
分类号:
R73
DOI:
-
文献标志码:
A
摘要:
锌铁调控蛋白(ZIP)4是一种锌离子转运蛋白,不仅参与肠道上皮细胞锌离子的吸收,而且在肿瘤的发生、发展中也起着十分重要的作用。ZIP4的过表达促进了多种上皮源性恶性肿瘤的发生及转移,然而抑制ZIP4的表达可以有效抑制肿瘤细胞的生长和侵袭。目前研究认为,ZIP4介导的肿瘤侵袭转移主要是通过促进EMT的发生、促进炎性介质的产生、促进血管新生等方式进行,而且ZIP4表达高低与肿瘤化疗耐药具有相关性。
Abstract:
-

参考文献/References:

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备注/Memo

备注/Memo:
基金项目 国家自然科学基金资助项目编号(81872206,81872495)
作者简介 朱婷婷(1993-),女,硕士在读,研究方向:头颈部肿瘤;
通信作者: 周旋,E-mail:byron2000zhou@sina.com
更新日期/Last Update: 2020-06-02