[1]Hanahan D, Weinberg R A.The hallmarks of cancer[J]. Cell,2000,100(1):57 [2]Huang W, Seo J, Willingham S B, et al. Learning from host-defense peptides: cationic, amphipathic peptoids with potent anticancer activity[J].PLoS One,2014,9(2):e90397 [3]Ding J, Chua P J, Bay B H, et al. Scorpion venoms as a potential source of novel cancer therapeutic compounds[J].Exp Biol Med,2014,239(4):387 [4] 胡楠, 卞筱泓, 许激扬.抗肿瘤活性多肽的研究现状[J].中国现代应用药学, 2015,31(9): 1155 [5] 刘光照, 张婕, 殷润婷.抗肿瘤多肽的研究新进展[J].药学进展, 2015,56(9): 671 [6]Tian R, Li Y, Gao M. Shikonin causes cell-cycle arrest and induces apoptosis by regulating the EGFR-NF-kappa B signalling pathway in human epidermoid carcinoma A431 cells[J].Biosci Rep,2015,35(2):e00189 [7] Russo L C, Araujo C B, Iwai L K,et al. A Cyclin D2-derived peptide acts on specific cell cycle phases by activating ERK1/2 to cause the death of breast cancer cells.[J].J Proteomics, 2017,151(1):24 [8]林秀坤,苏硕楠.靶向细胞凋亡的海洋抗肿瘤多肽药物研究进展[J].山东科学,2015,28(3):16 [9]Thakur R, Kini S, Kurkalang S A, et al. Mechanism of apoptosis induction in human breast cancer MCF-7 cell by Ruviprase, a small peptide from Daboia russelii russelii venom[J].Chem Biol Interact,2016,258(1):297 [10]Adams J M. Therapeutic potential of a peptide targeting BCL-2 cell guardians in cancer[J].J Clin Invest , 2012, 122(6):1965 [11]庄海峰,郑智茵,陈均法,等.蝎毒抗癌多肽对HL-60细胞凋亡及Bcl-2/P53基因表达的影响[C]//中华中医药学会第二届岐黄论坛—血液病中医药防治分论坛论文集,2014,北京,2014:1 [12]Bellou S, Pentheroudakis G, Murphy C, et al. Anti-angiogenesis in cancer therapy: Hercules and hydra[J].Cancer Lett,2013,338(2):219 [13]Masuzawa T, Fujiwara Y, Okada K, et al. Phase I/II study of S-1 plus cisplatin combined with peptide vaccines for human vascular endothelial growth factor receptor 1 and 2 in patients with advanced gastric cancer[J].Int J Oncol,2012,41(4):1297 [14]Bae S M, Kim J H, Chung S W, et al. An apoptosis-homing peptide-conjugated low molecular weight heparin-taurocholate conjugate with antitumor properties[J].Biomaterials,2013,34(8):2077 [15]Presicce P, Giannelli S, Taddeo A, et al. Human defensins activate monocyte-derived dendritic cells, promote the production of proinflammatory cytokines, and up-regulate the surface expression of CD91[J].J Leukoc Biol,2009,86(4):941 [16]Mansourian M, Badiee A, Jalali S A, et al. Effective induction of anti-tumor immunity using p5 HER-2/neu derived peptide encapsulated in fusogenic DOTAP cationic liposomes co-administrated with CpG-ODN[J].Immunol Lett,2014,162(1, A):87 [17]Schiffman M, Wentzensen N. Towards therapeutic vaccination against cervical precancer[J].Lancet,2015,386(18):2036 [18]Xiao Y F, Jie M M, Li B S, et al. Peptide-Based treatment: a promising cancer therapy[J].Jouranl of Immunology Research,2015,2015(6):761820 [19]Albrethsen J, Moller C H, Olsen J A. Human neutrophil peptides 1,2 and 3 are biochemical markers for metastatic colorectal cancer[J].Euro J Cancer,2006,42(17):3057 [20]Cicatiello V, Apicella I, Tudisco L, et al. Powerful anti-tumor and anti-angiogenic activity of a new anti-vascular endothelial growth factor receptor 1 peptide in colorectal cancer models[J].Oncotarget, 2015,6(12):10563 [21]Wang C, Zhao M, Liu Y R, et al. Suppression of colorectal cancer subcutaneous xenograft and experimental lung metastasis using nanoparticle-mediated drug delivery to tumor neovasculature[J]. Biomaterials,2014,35(4):1215 [22]Luna Vital D A, De Mejia E G, Dia V P, et al. Peptides in common bean fractions inhibit human colorectal cancer cells[J].Food Chem , 2014,157(11):347 [23]Siegel R, Ma J M, Zou Z H, et al. Cancer statistics, 2014[J].CA Cancer J Clin,2014,64(1):9 [24]Ohtsu A. Current status and future prospects of chemotherapy for metastatic gastric cancer:a review[J].Gastric Cancer,2005,8(2):95 [25]Ishikawa H, Imano M, Shiraishi O, et al. Phase I clinical trial of vaccination with LY6K-derived peptide in patients with advanced gastric cancer[J].Gastric Cancer,2014,17(1):173 [26]Zhang B, Zhang Z L, Zhang X F, et al. Serological antibodies against LY6K as a diagnostic biomarker in esophageal squamous cell carcinoma[J]. Biomarkers,2012,17(4):372 [27]Ishikawa N, Takano A, Yasui W, et al. Cancer-testis antigen lymphocyte antigen 6 complex locus K is a serologic biomarker and a therapeutic target for lung and esophageal carcinomas[J].Cancer Res,2007,67(24):11601 [28]Iwahashi M, Katsuda M, Nakamori M A, et al. Vaccination with peptides derived from cancer-testis antigens in combination with CpG-7909 elicits strong specific CD8+T cell response in patients with metastatic esophageal squamous cell carcinoma[J].Cancer Sci,2010,101(12):2510 [29]Higashihara Y, Kato J, Serizawa N, et al. Phase I clinical trial of peptide vaccination with Urlc10 and VEGFR1 epitope peptides in patients with advanced gastric cancer[J].Gastroenterology,2012,142(5, 1):S628 [30]Nishida S, Koido S, Takeda Y, et al. Wilms tumor gene ( WT1) peptide- based cancer vaccine combined with gemcitabine for patients with advanced pancreatic cancer[J].J Immunother ,2014,37(2):105
[1]张娅洁,王慧媛,陈应之,等.经穿膜肽与PEG修饰的核糖体失活蛋白Gelonin抗肿瘤作用的研究[J].天津医科大学学报,2015,21(05):369.
ZHANG Ya-jie,WANG Hui-yuan,CHEN Ying-zhi,et al.Study on cell-penetrating peptide modified and PEGylated ribosome inactive protein Gelonin[J].Journal of Tianjin Medical University,2015,21(04):369.
[2]蒋腾,朱仲玲综 述,阎昭审 校.二甲双胍抗肿瘤作用的研究进展[J].天津医科大学学报,2020,26(06):577.
[3]杜双双,赵红平,综述,等.多肽类药物对肿瘤免疫调节的影响及其机制研究进展[J].天津医科大学学报,2018,24(04):363.
作者简介 王美飒(1992-),女,硕士在读,研究方向:肿瘤临床药理;通信作者:阎昭, E-mail:yanzhaopaper@163.com。