[1]Garra A,Vieira P.Regulatory T cells and mechanisms of immune system control[J].Nat Med,2004,10( 8) : 801 [2]Neta R,Salvin S B.Specific suppression of delayed hypersensitivity:the possible presence of a suppressor B cell in the regulation of delayed hypersensitivity[J].J Immunol,1974,113 ( 6) : 1716 [3]Kitamura D,Roes J,Kühn R,et al.A B cell-deficient mouse by targeted disruption of the membrate exon of the immunoglobulinmu chain gene[J].Nature,1991,350( 6317) : 423 [4]Wolf S D,Dittel B N, Janeway C A. Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice[J]. Exp Med,1996,184( 6) :271 [5]Mizoguchi E,Mizoguchi A,Preffer F I,et al.Regulatory role of mature B cells in a murine model of inflammatory bowel disease[J].Int Immunol,2000,12( 5) : 597 [6]Yanaba K,Bouaziz J D,Haas K M,et al.A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses[J].Immunity,2008,28( 5) : 639 [7]Blair P A,Norena L Y,Flores-Borja F,et al.CD19+ CD24hiCD38hi B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic lupus erythematosus patients[J].Immunity,2010,32( 1) : 129 [8]Hardy R R,Hayakawa K.B cell development pathways[J].Annu Rev Immunol,2001, 19: 595 [9]Xu M,Mizoguchi I,Morishima N,et al. Regulation of antitumor immune responses by the IL-12 family cytokines,IL-12,IL-23,and IL-27[J].Clin Dev Immunol,2010,2010:832454 [10]Fillatreau S.Cytokine-producing B cells as regulators of pathogenic and protective immune responses[J].Ann Rheum Dis,2013,72(Suppl 2):ii80 [11]Lampropoulou V,Hoehlig K,Roch T,et al.TLR-activated B cells suppress T cell-mediated autoimmunity[J].J Immunol,2008,180(7) : 4763 [12] Mauri C, Menon M . The expanding family of regulatory B cells[J]. Int Immunol ,2015,27(10):479 [13]Bouaziz J D,Calbo S,Maho-Vaillant M,et al. IL-10 produced by activated human B cells regulates CD4+ T-cell activation in vitro[J].Eur J Immunol,2010,40( 10) : 2686 [14]Kapsogeorgou E K,Moutsopoulos H M,Manoussakis M N. Functional expression of a costimulatory B7.2 (CD86) protein on human salivary gland epithelial cells that interacts with the CD28 receptor,but has reduced binding to CTLA4[J]. J Immunol,2001,166(5):3107 [15]Herve M,Isnardi I,Ng Y S,et al.CD40 ligand and MHC class Ⅱexpression are essential for human peripheral B cell tolerance[J].J Exp Med,2007,204( 7) : 1583 [16]Laleh M,Richard L M,Claude L. Regulatory B and T cells in infections[J]. Mic Infec,2008,10(9):1030 [17]Zhang X,Deriaud E,Jiao X,et al. Type I interferons protect neonates from acute inflammation through interleukin 10-producing B cells[J]. J Exp Med,2007,121(4):1107 [18]刘学磊,刘玉梅,丁剑冰,等.调节性B细胞在感染免疫中的作用研究进展[J].中国病原生物学杂志,2014,9( 4):381 [19]Evans J G,Chavez-Rueda K A,Eddaoudi A,et al. Novel suppressive function of transitional 2B cells in experimental arthritis[J].J Immunol,2007,178(12):7868 [20] Stüve O, Warnke C, Deason K , et al. CD19 as a molecular target in CNS autoimmunity[J]. Acta Neuropathol, 2014 ,128(2): 177 [21]Matsushita T,Horikawa M,Iwata Y,et al. Regulatory B cells(B10 cells)and regulatory T cells have independent roles in controlling experimental autoimmune encephalomyelitis initiation and late-phase immunopathogenesis[J]. Immunol,2010,185(4):2240 [22]Inaki S. Rationale for B cell targeting in SLE[J]. Semin Immunopathol, 2014,36(3):365 [23]Xi B,Yu F,Zi M,et al. Proportions of immune regulatory cells and their subsets in peripheral blood of patients with Graves’ disease [J]. Cell Mol Immuno,2014,30(11):1190 [24]冯锦山,迟宏罡,郑学宝.人体调节性B细胞表型及相关功能分子研究[J].细胞与分子免疫学杂志, 2013,29( 3):320 [25]Stolp J,Turka L A,Wood K J. B cells with immune-regulating function in transplantation[J]. Nat Rev Nephrol,2014,10(7):389 [26]Yeung M Y,Ding Q,Brooks CR,et al. TIM-1 signaling is required for maintenance and induction of regulatory B cells[J].Am J Transplant,2015,15 ( 4) : 942
通信作者:张鹏,E-mail:zhp_tjgh@163.com。