|本期目录/Table of Contents|

[1]谷 寅,何向辉,赵 科. 结节性甲状腺肿合并偶发乳头状癌临床分析[J].天津医科大学学报,2015,21(03):245-247.
　GU Yin,HE Xiang-Hui,ZHAO Ke.Incidental papillary carcinoma in nodular goiter[J].Journal of Tianjin Medical University,2015,21(03):245-247.
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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
21卷
期数:
2015年03期
页码:
245-247
栏目:
临床医学
出版日期:
2015-05-20

文章信息/Info

Title:
Incidental papillary carcinoma in nodular goiter
文章编号:
1006-8147（2015）03-0245-03
作者:
谷 寅; 何向辉; 赵  科
 
（天津医科大学总医院普通外科，天津 300052）
Author(s):
GU Yin; HE Xiang-Hui; ZHAO Ke
（Department of General Surgery ，General Hospital， Tianjin Medical University ，Tianjin 300052 ，China）
关键词:
结节性甲状腺肿; 甲状腺乳头状癌; 预后
Keywords:
 ; nodular goiter ; papillary thyroid carcinoma ;  prognosis
分类号:
R736.1
DOI:
-
文献标志码:
A
摘要:
目的：总结结节性甲状腺肿合并偶发乳头状癌（IPC）的临床特点和治疗要点。方法：回顾性分析92例结节性甲状腺肿合并偶发乳头状癌患者的临床资料及病理特点。结果： 92例（7.2%）结节性甲状腺肿合并偶发乳头状癌患者，男性15例（17.4%），女性77例（82.6%），最大良性结节平均直径为（2.37±0.68）cm，单侧发病60例（65.2%），双侧发病32例（34.8%），偶发乳头状癌直径为0.1～1.0 cm，平均直径（0.43±0.27）cm，91例（98.9%）为单发癌灶，1例（1.1%）为单侧多发癌灶（2个），92例（100%）患者术后长期口服左甲状腺素片，80例（87%）得到随访，随访时间7～72月，未发现复发及淋巴结转移。结论：结节性甲状腺肿合并偶发乳头状癌发病率为7.2%，对术前诊断为结节性甲状腺肿患者，单侧发病实施腺叶切除，双侧发病实施腺叶+次全切除或近全切除术，术后诊断为偶发乳头状癌，一般预后良好，但应长期口服左甲状腺素片抑制治疗，定期随访。
Abstract:
Objective: To investigate the clinical features and principles for the diagnosis and treatment of incidental papillary carcinoma (IPC) in goiter. Methods: Ninety-two patients with different thyroid carcinoma in nodular goiter admitted from July 2008 to December 2013 were retrospectively analyzed. Results: Overall, Ninety-two IPCs were recorded (male 15,female 77). The largest benign nodules had an average diameter(2.37±0.68)cm , the diameter of IPC ranged from 0.1～1.0 cm and the average diameter was (0.43±0.27)cm. Ninety-one cases(98.9%) were unifocal, and 1 case was unilateral multifocal(2 centers), 92 cases(100%) took L-T4 post operation for long time, 80 cases were followed up for 7～72 months and no recurrence or metastasis was found. Conclusion: The overall incidence of IPC in nodular goiter was 7.2%. For IPC patients who are considered nodular goiter receiving lobectomy or near-total thyroidectomy before operation, reoperation is unnecessary. However, L-T4 is regular drug for post-operation patients. Regular following-up is also essential.

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备注/Memo

备注/Memo:
作者简介 谷寅（1986-），男，硕士在读，研究方向：普通外科；

通信作者：何向辉,E-mail：humphreyhe@163.com。

更新日期/Last Update: 2015-05-27