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[1]王 琮,张士忠,何佳佳,等.多模式神经电生理监测指导手术切除脊髓髓内肿瘤的临床研究[J].天津医科大学学报,2015,21(02):136-139.
　WANG Cong,ZHANG Shi-zhong,HE Jia-jia,et al.Multimodal intraoperative neurophysiologic monitoring and clinical neurologic outcomes in patients with intrmedullary spine tumors[J].Journal of Tianjin Medical University,2015,21(02):136-139.
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多模式神经电生理监测指导手术切除脊髓髓内肿瘤的临床研究(PDF)
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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
21卷
期数:
2015年02期
页码:
136-139
栏目:
临床医学
出版日期:
2015-03-20

文章信息/Info

Title:
Multimodal intraoperative neurophysiologic monitoring and clinical neurologic outcomes in patients with intrmedullary spine tumors
文章编号:
1006-8147（2015）02-0136-04
作者:
王 琮1; 张士忠2; 何佳佳1; 刘 通1; 李 红1; 刘 辉1; 朱 涛1
（1.天津医科大学总医院神经外科 ，天津 300052；2.山东省泰安市中心医院神经外科 ，泰安 271000）
Author(s):
 WANG Cong1; ZHANG Shi-zhong2; HE Jia-jia1 ; LIU Tong1; LI Hong1 ; LIU Hui1 ; ZHU Tao1
(1.Department of Neurosurgery, General Hospital, Tianjin Medical University ,Tianjin 300052, China ;2.Department of Neurosurgery, The Central Hospital of Taian ,Taian 271000, China)
关键词:
脊髓髓内肿瘤; 术中神经电生理监测; 脊髓神经功能
Keywords:

spinal cord tumor;  intraoperative neurophysiologic monitoring;  spinal nerve function

分类号:
R61
DOI:
-
文献标志码:
A
摘要:
目的：探讨多模式术中神经电生理监测技术（MIOM）在脊髓髓内病变手术中预测脊髓神经功能的价值。方法：回顾性分析34 例脊髓髓内病变切除术，术中应用多模式神经电生理监测技术（感觉诱发电位、肌源性运动诱发电位和肌电图）监测脊髓功能，记录患者术前、术后脊髓神经功能状态及术中电生理监测数据。结果：34 例脊髓髓内肿瘤手术全切28 例，大部切除6 例。术中有21 例达到报警标准，一过性改变14 例，永久性改变7 例。术后6 例患者出现脊髓功能加重，超过6个月的长期随访中，其中2 例神经功能得到有效恢复；MIOM远期阴性预测值为100%，阳性预测值为57.1%。结论：MIOM在脊髓髓内肿瘤术中能及时发现神经损伤，有效地保护神经功能，其信号改变对术后脊髓神经功能有预测作用。
Abstract:

Objective：To assess the predictive capability of multimodal intraoperative neurophysiologic monitoring（MIOM）in decompression for intramedullary spine tumors. Methods： Thirty-four cases of intramedullary spine tumors were treated with MIOM [somatosensory evoked potentials (SSEP), motor evoked potentials (MEP)and electromyography (EMG)]. Preoperative and postoperative neurologic status and intraoperative neurophysiologic data were collected. Results：Intramedullary spinal cord tumors in 34 cases were completely removed in 28 cases, and partially in 6 cases. Twenty-one cases met inclusion criteria with 14 transient changes and 7 persistent changes. Six cases developed new neurologic deficits after surgery and 2 of them had obtained recovery in the 6-months follow-up. MIOM long-term negative predictive capability was 100% while positive predictive capability was 57.1%. Conclusion：MIOM in intramedullary spinal cord lesions can accurately locate nerve injury during operation and effectively protect the nerve functions. Signal changes in MIOM can predict postoperative spinal cord nerve function.

参考文献/References:

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备注/Memo

备注/Memo:

作者简介 王琮（1987-），男，硕士在读，研究方向：神经外科；

通信作者：朱涛，E-mail：zhutao5@126.com。

更新日期/Last Update: 2015-03-24