|本期目录/Table of Contents|

[1]陈 琳,袁如玉.冠心病患者血清胆红素、血尿酸水平与冠状动脉钙化的关系[J].天津医科大学学报,2015,21(02):134-135.
点击复制

冠心病患者血清胆红素、血尿酸水平与冠状动脉钙化的关系(PDF)
分享到：

《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
21卷
期数:
2015年02期
页码:
134-135
栏目:
临床医学
出版日期:
2015-03-20

文章信息/Info

Title:
-
文章编号:
1006-8147（2015）02-0134-02
作者:
陈 琳; 袁如玉
（天津医科大学第二医院心脏科，天津 300211 ）
Author(s):
-
关键词:
冠状动脉钙化; 胆红素; 尿酸; 冠状动脉造影
Keywords:
-
分类号:
R541.4
DOI:
-
文献标志码:
A
摘要:
 目的：探讨冠心病患者血清总胆红素、血尿酸水平与冠状动脉钙化的关系。方法：回顾性分析冠状动脉造影确诊的冠心病患者192例，将其分为钙化组和非钙化组。实验室检查测定各组的血清总胆红素及血尿酸浓度，分析不同组别血清总胆红素、血尿酸水平与冠脉钙化的关系。结果：两组一般资料基本一致，钙化组总胆红素水平均低于对照组（P＜0.05），血尿酸水平高于对照组（P＜0.05）。结论：冠心病患者血清胆红素水平与冠状动脉钙化负相关，血尿酸水平与冠状动脉钙化正相关，提示低胆红素、高尿酸水平可能是冠状动脉钙化的危险因素。
Abstract:
-

参考文献/References:

[1]罗玮．冠状动脉钙化的研究进展[J]．医学综述，2011，17（17）：2644
[2]周业波，陆峥飞，齐永芬．糖尿病与血管钙化[J]．中国动脉硬化杂志，2009，17（3）：241
[3]Kimm H, Yun J E, Jo J, et al. Low serum bilirubin level as an Independent predictor of stroke incidence: a prospective study in Korean men and women[J]. Stroke, 2009, 40(11): 3422
[4]Horsfall L J, Nazareth I, Petersen I. Cardiovascular events as a functionof serum bilirubin levels in a large,statin-treated cohort[J]. Circulation, 2012, 126(22): 2556.
[5]Schwertner H A, Jackson W G, Tolan G. Association of low serum concentration of bilirubin with increased risk of coronary artery disease[J]. Clin Chem, 1994, 40(1): 18
[6]De Ba ran an O, Rao M, Ferris C D, et al. Biliverdin reductase:amajor physiologic cytoprotectant[J]. Proc Natl Acad Sci U S A, 2002, 99(25): 16093
[7]林青，熊尚全，许少锋，等．胆红素及氧化修饰低密度脂蛋白与冠心病的关系[J]．临床心血管病杂志，2002，18（5）：204
[8]赵韧，李小虎，程自平，等．血清胆红素水平与冠脉病变的关系[J]．安徽医学，2014，35（1）：12
[9]Franchini M, Targher G, Lippi G. Serum bilirubin levels and cardiovascular disease risk:a Janus BifronsAdv Clin Chem 2010,50: 47
[10]Leopold J A, Loscalzo J. Oxidative enzymopathies and vascular disease[J]. Arterioscler Thromb Vasc Biol, 2005, 25(7): 1332
[11]Brodov Y, Behar S, Goldenberg I, et al. Usefulness of combining serum uric acid and C-reactive protein for risk stratification of patients with coronary artery disease (Bezafibrate Infarction Prevention [BIP] study)[J]. Am J Cardiol, 2009, 104(2): 194
[12]Atar A I, Y?lmaz O C, Ak?n K, et al. Serum uric acid level is an Independent risk factor for presence of Calcium in coronary arteries: an observational case-controlled study[J]. Anadolu Kardiyol Derg, 2013, 13(2): 139
[13]Neogi T, Terkeltaub R, Ellison R C, et al. Serum urate is not associated with coronary artery calcification:the NHLBI family heart study[J]. J Rheumatol, 2011, 38(1): 111
[14]Coutinho T D, Turner S T, Peyser P A, et al. Associations of serum uric acid with markers of inflammation, metabolic syndrome, and subclinical coronary atherosclerosis[J]. Am J Hypertens, 2007, 20(1): 83
[15]Johnson R J, Kang D H, Feig D, et al. Is there a pathogenetic role for uric acid in hypertension and cardiovascular and renal disease?[J]. Hypertension, 2003, 41(6): 1183

相似文献/References:

[1]邢云芝,李春君,张秋梅,等.中老年男性2型糖尿病患者骨质疏松症与血清胆红素的相关性[J].天津医科大学学报,2015,21(05):426.
　XING Yun-zhi,LI Chun-jun,ZHANG Qiu-mei,et al.Relationship between serum bilirubin levels and osteoporosis in middle and old aged male patients with type 2 diabetes mellitus[J].Journal of Tianjin Medical University,2015,21(02):426.
[2]刘洪梅综述,李广平审校. 血清胆红素在冠心病患者中的应用价值研究进展[J].天津医科大学学报,2014,20(06):506.

备注/Memo

备注/Memo:

作者简介 陈琳（1988-），女，硕士在读，研究方向：高血压；通信作者：袁如玉，E-mail : yuanruyu@medmail.com.cn。

更新日期/Last Update: 2015-03-24