|本期目录/Table of Contents|

[1]闫喆.主动循环呼吸技术对进展性纤维化性间质性肺病患者的治疗效果[J].天津医科大学学报,2022,28(04):414-417.
 YAN Zhe.Effect of active cycle of breathing technologies on patients with progressive fibrotic interstitial lung disease[J].Journal of Tianjin Medical University,2022,28(04):414-417.
点击复制

主动循环呼吸技术对进展性纤维化性间质性肺病患者的治疗效果(PDF)
分享到:

《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:
28卷
期数:
2022年04期
页码:
414-417
栏目:
临床医学
出版日期:
2022-07-20

文章信息/Info

Title:
Effect of active cycle of breathing technologies on patients with progressive fibrotic interstitial lung disease
文章编号:
1006-8147(2022)04-0414-04
作者:
闫喆
(天津医科大学第二医院康复医学科,天津 300211)
Author(s):
YAN Zhe
(Department of Rehabilitation,The Second Hospital of Tianjin Medical University,Tianjin 300211,China)
关键词:
肺纤维化结缔组织病主动循环呼吸技术肺康复
Keywords:
pulmonary fibrosis connective tissue disease active circulatory breathing technology lung rehabilitation
分类号:
R493
DOI:
-
文献标志码:
A
摘要:
目的:观察主动循环呼吸技术(ACBT)对进展性纤维化性间质性肺病(PF-ILD)患者不同阶段的治疗效果。方法:收集2018年12月至2020年12月天津医科大学第二医院康复医学科就诊的48例PF-ILD患者,采用随机数字表法分为对照组和试验组,各24例。所有患者均接受为期18周康复治疗,分为院内指导和家庭锻炼阶段。对照组接受常规运动康复,试验组在对照组的基础上增加ACBT训练。在各阶段开始、结束时分别进行用力肺活量占预计值的百分比(FVC%pred)、一氧化碳弥散占预计值的百分比(DLCO%pred)、涎液化糖链抗原-6(KL-6)、6 min步行试验(6MWT)及圣乔治呼吸问卷(SGRQ)测试,所得数据使用t检验或U检验。结果:在院内指导阶段结束时,试验组FVC%pred、DLCO%pred、6MWT、SGRQ评分优于对照组(t/z=4.154、3.280、2.540、-7.757,均P<0.05),KL-6与对照组相比,差异无统计学意义(P>0.05)。在家庭锻炼阶段结束时,试验组FVC%pred、DLCO%pred、SGRQ评分优于对照组(t/z=4.170、2.449、-6.246,均P<0.05),6MWT、KL-6为与对照组无差异(均P>0.05)。结论:在院内指导阶段和家庭锻炼阶段,ACBT对PF-ILD患者治疗效果较好,值得推广。
Abstract:
Objective: To observe the therapeutic effect of active cycle of breathing technologies(ACBT) on patients with progressive fibrotic interstitial lung disease(PF-ILD). Methods:A total of 48 patients with PF-ILD from December 2018 to December 2020 in the Department of Rehabilitation,The Second Hospital of Tianjin Medical University were collected and randomly divided into control group and experimental group,with 24 cases in each group. All patients received rehabilitation treatment for 18 weeks,which was divided into hospital guidance and family exercise. The control group received routine exercise rehabilitation,and the experimental group increased ACBT training on the basis of the control group. At the beginning and end of each stage,the percentage of forced vital capacity in the predicted value(FVC% pred),the percentage of carbon monoxide dispersion in the predicted value(DLCO% pred),salivary liquefied sugar chain antigen-6(KL-6),six-minute walk test(6MWT)and St. George′s Respiratory Questionnaire (SGRQ)were tested respectively. The data were tested by t-test or U-test. Results:At the end of the in-hospital guidance stage,FVC% pred,DLCO% pred,6MWT and SGRQ in the experimental group were significantly better than those in the control group(t/z=4.154,3.280,2.540,-7.757,all P<0.05),and there was no difference in KL-6 between the experimental group and the control group(t =-0.479,P > 0.05). At the end of family exercise, FVC% pred,DLCO%pred and SGRQ in the experimental group were significantly better than those in the control group(t/z=4.170, 2.449,-6.246,all P<0.05),and there was no difference in 6MWT and KL-6 between the experimental group and the control group(t/z=-1.495,-0.004,all P>0.05). Conclusion:In the hospital guidance stage and family exercise stage,ACBT has a good therapeutic effect on PF-ILD patients,which is worthy of popularization and use.

参考文献/References:

[1] JO H E,GLASPOLE I,MOODLEY Y,et al. Disease progression in idiopathic pulmonary fibrosis with mild physiological impairment:analysis from the Australian IPF registry[J]. BMC Pulm Med,2018,18(1):19.
[2] FLAHERTY K R,BROWN K K,WELLS A U,et al.Design of the PF-ILD trial:a double-blind,randomised,placebo-controlled phase Ⅲ trial of nintedanib in patients with progressive fibrosing interstitial lung disease[J]. BMJ Open Respir Res,2017,4(1):212-219.
[3] NICI L,ZUWALLACK R. Chronic obstructive pulmonary disease—evolving concepts in treatment:advances in pulmonary rehabilitation[J]. Semin Respir Crit Care Med,2015,36(4):567-574.
[4] TAKIZAWA A,KAMITA M,KONDOH Y,et al. Current monitoring and treatment of progressive fibrosing interstitial lung disease:a survey of physicians in Japan,the United States,and the European Union[J]. Curr Med Res Opin,2021,37(2):327-339.
[5] WIJSENBEEK M,KREUTER M,OLSON A,et al. Progressive fibrosing interstitial lung diseases:current practice in diagnosis and management[J]. Curr Med Res Opin,2019,35(11):2015-2024.
[6] YANG M,ZHONG J D,ZHANG J E,et al. Effect of the self-efficacy-enhancing active cycle of breathing technique on lung cancer patients with lung resection:aquasi-experimental trial[J]. Eur J Oncol Nurs,2018,34:1-7.
[7] 江宇,金洪.进展性纤维化性间质性肺疾病的概念及临床意义[J].中华结核和呼吸杂志,2021,44(6):566-568.
[8] COTTIN V,HIRANI N A,HOTCHKIN DL,et al. Presentation,diagnosisand clinical course of the spectrum of progressive-fibrosing interstitial lung diseases[J]. Eur Respir Rev,2018,27(150):76-87.
[9] PEREZ-BOGERD S,WUYTS W,BARBIER V,et al. Short and long-term effects of pulmonary rehabilitation in interstitial lung diseases:a randomised controlled trial[J]. Respir Res,2018,19(1):182-192.
[10] GELTSER B I,KURPATOV I G,DEJ A A,et al. Respiratory muscles dysfunction and respiratory diseases[J]. Ter Arkh,2019,91(3):93-100.
[11] AGUSTI A,BEL E,THOMAS M,et al. Treatable traits:toward precision medicine of chronic airway diseases[J]. Eur Respir J,2016,47(2):410-419.
[12] SAWYER A,CAVALHERI V,HILL K. Effects of high intensity interval training on exercise capacity in people with chronic pulmonary conditions:a narrative review[J]. BMC Sports Sci Med Rehabil,2020,12:22.
[13] SUZUKI A,KONDOH Y,SWIGRIS J J,et al. Performance of the St George's Respiratory Questionnaire in patients with connective tissue disease-associated interstitial lung disease[J]. Respirology,2018,23(9):851-859.
[14] 王龙平,彭继海,张鸣生.主动呼吸循环技术在非小细胞肺癌肺叶切除术后快速康复中的临床应用[J].中国康复医学杂志,2018,33(6):642-646.

相似文献/References:

[1]董笑影 综述,魏 蔚 审校. 沙利度胺治疗肺纤维化新进展[J].天津医科大学学报,2015,21(03):272.
[2]王硕,张军,严一杰,等.肺癌合并肺纤维化患者在肺癌根治术中手术风险的评估[J].天津医科大学学报,2018,24(02):156.
 WANG Shuo,ZHANG Jun,YAN Yi-jie,et al.Risk assessment of lung cancer combined with pulmonary fibrosis in lung cancer radical surgery[J].Journal of Tianjin Medical University,2018,24(04):156.
[3]徐雷倩,曹 洁.FSTL1促进间歇性低氧诱导的肺成纤维细胞活化[J].天津医科大学学报,2019,25(05):446.
 XU Lei-qian,CAO Jie.FSTL1 promotes intermittent hypoxia-induced lung fibroblast activation[J].Journal of Tianjin Medical University,2019,25(04):446.
[4]王 慧,张 娜,赵 音,等.结缔组织病相关动脉性肺动脉高压临床特点分析[J].天津医科大学学报,2020,26(01):32.
 WANG Hui,ZHANG Na,ZHAO Yin,et al.Clinical features of connective tissue disease associated Pulmonary artery hypertension[J].Journal of Tianjin Medical University,2020,26(04):32.

备注/Memo

备注/Memo:
作者简介:闫喆(1993-),女,康复治疗师,学士,研究方向:康复治疗学,E-mail:421877359@qq.com。
更新日期/Last Update: 2022-07-20