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《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]

卷:

25卷

期数:

2019年05期

页码:

488-492+495

栏目:

临床医学

出版日期:

2019-09-20

文章信息/Info

Title:

Effects of marital status on patient prognosis in oligodendroglioma

文章编号:

1006-8147(2019)05-0488-05

作者:

于雪迪; 佘春华; 孙增峰; 尹 强; 纪昕欣; 马 莉; 李文良

（天津医科大学肿瘤医院脑系肿瘤科，国家肿瘤临床医学研究中心，天津市“肿瘤防治”重点实验室，天津市恶性肿瘤临床医学研究中心，天津300060）

Author(s):

YU Xue-di;  SHE Chun-hua;  SUN Zeng-feng;  YIN Qiang;  JI Xin-xin;  MA Li;  LI Wen-liang

（Department of Brain Oncology, Cancer Institute and Hospital, Tianjin Medical University, National Clinical Research Center for Cancer,Key Laboratoryof Cancer Prevention and Therapy, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China）

关键词:

少突胶质细胞瘤; 婚姻状态; 预后; SEER规划

Keywords:

oligodendroglioma;  marital status;  prognosis;  SEER Program

分类号:

R739.41

DOI:

-

文献标志码:

A

摘要:

目的：探讨少突胶质细胞瘤患者婚姻状况与预后之间的关系。方法：纳入SEER数据库中自1973-2015年诊断为少突胶质细胞瘤的4 282例患者。通过Kaplan-Meier法分析患者生存率，Cox回归模型分析影响生存的独立危险因素。结果：单因素分析显示，性别、年龄、手术情况、原发灶部位、婚姻状况与少突胶质细胞瘤患者生存期相关（P<0.01）。多因素分析发现，婚姻状况是患者生存的独立预后因素（P<0.05），在相同性别、年龄范围、手术治疗情况下，丧偶仍是患者的独立危险因素（P<0.01）。结论：婚姻状况与少突胶质细胞瘤患者生存期密切相关，丧偶增加患者的死亡风险。

Abstract:

Objective: To investigate the impact of marital status on patient prognosis in oligodendroglioma. Methods:We collected 4282 eligible patients with oligodendroglioma from SEER database from 1973 to 2015. Kaplan-Meier methods were used to analyze the patients’ survival, and Cox regression models were applied to analyze independent risk factors for patients’overall survival in oligodendroglioma. Results: Univariate analysis showedthat gender, age,surgery status, and primary siteandmarital status were significantly associated with patients’ overall survival in oligodendroglioma（P <0.01）. Multivariate analysis found that marital status wasthe independent prognostic factor for patients’ overall survival（P <0.05）. Widowed remained the independent risk factor for patients with the same gender, age range or surgery status（P<0.01）. Conclusion: Marital status might be closely associated with patients’ overall survival in oligodendroglioma, and widowed may increase the risk of death in patients.

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备注/Memo

备注/Memo:

基金项目 国家自然科学基金资助项目（81702481）；天津市自然科学基金资助项目（15JCQNJC44800）
作者简介 于雪迪（1992-），女，硕士在读，研究方向：颅脑肿瘤；通信作者：李文良，E-mail：Liwenliang2338@163.com。

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更新日期/Last Update: 2019-10-11