[1]陆雨郡,杨金花,曹鸣芯,等.激光辅助治疗种植体周炎的疗效及对牙周菌群的影响[J].天津医科大学学报,2026,32(03):256-259,289.[doi:10.20135/j.issn.1006-8147.2026.03.0256]
LU Yujun,YANG Jinhua,CAO Mingxin,et al.Efficacy of laser-assisted therapy for peri-implantitis and its impact on periodontal microbiota[J].Journal of Tianjin Medical University,2026,32(03):256-259,289.[doi:10.20135/j.issn.1006-8147.2026.03.0256]
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激光辅助治疗种植体周炎的疗效及对牙周菌群的影响(PDF)
《天津医科大学学报》[ISSN:1006-8147/CN:12-1259/R]
- 卷:
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32卷
- 期数:
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2026年03期
- 页码:
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256-259,289
- 栏目:
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临床医学
- 出版日期:
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2026-05-20
文章信息/Info
- Title:
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Efficacy of laser-assisted therapy for peri-implantitis and its impact on periodontal microbiota
- 文章编号:
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1006-8147(2026)03-0256-05
- 作者:
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陆雨郡1; 杨金花1; 曹鸣芯2; 李志远1
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1.贵州医科大学附属口腔医院牙周黏膜科,贵阳550004;2.天津医科大学口腔医院正畸科,天津300070
- Author(s):
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LU Yujun1; YANG Jinhua1; CAO Mingxin2; LI Zhiyuan1
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1.Department of Periodontology and Mucosa, Stomatological Hospital Affiliated to Guizhou Medical University, Guiyang 550004, China;2.Department of Orthodontics, Hospital of Stomatology, Tianjin Medical University, Tianjin 300070, China
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- 关键词:
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种植体周炎; 660 nm激光; 牙周组织修复; 牙周菌群
- Keywords:
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peri-implantitis; 660 nm laser; periodontal tissue repair; periodontal microbiota
- 分类号:
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R782.1
- DOI:
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10.20135/j.issn.1006-8147.2026.03.0256
- 文献标志码:
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A
- 摘要:
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目的:探讨激光联合常规保守治疗种植体周炎的临床疗效及对牙周菌群结构的影响。方法:选取2022年12月—2025年6月贵州医科大学附属口腔医院收治的90例种植体周炎患者,随机分为对照组(45例,常规机械菌斑清除)与激光组(45例,常规治疗基础上联合激光照射),治疗12周,比较两组临床有效率、种植体周临床指标[探诊深度(PD)、菌斑指数(PLI)、临床附着丧失(CAL)、龈沟出血指数(SBI)]以及牙周菌群水平[牙龈卟啉单胞菌(Pg)、齿垢密螺旋体(Td)、具核梭杆菌(Fn)、中间普氏菌(Pi)]。结果:治疗12周后,激光组总有效率为95.56%(43/45)显著高于对照组77.78%(35/45)(χ2=6.154,P=0.013);两组PD、PLI、CAL、SBI均较治疗前显著降低(均P<0.05),且激光组改善幅度均显著优于对照组(t=5.656、4.770、6.019、2.386,均P<0.05)。两组牙周组织中Pg、Td、Fn、Pi水平均较治疗前明显下降(均P<0.05),且激光组各致病菌水平下降幅度显著大于对照组(t=6.499、8.885、3.055、6.062,均P<0.05)。结论:激光联合常规保守治疗可显著提升种植体周炎的临床疗效,有效抑制牙周致病菌增殖,促进种植体周组织修复。
- Abstract:
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Objective: To investigate the clinical efficacy of laser combined with conventional conservative treatment for peri-implan-titis and its impact on the structure of periodontal microbiota. Methods: A total of 90 patients with peri-implantitis admitted to the Stomatological Hospital Affiliated to Guizhou Medical University between December 2022 to June 2025 were randomly divided into control group(45 cases, routine mechanical plaque removal) and laser group(45 cases, laser irradiation combined with the basis of routine treatment). All patients were treated for 12 weeks. The clinical effective rate, peri-implant clinical indexes [probing depth (PD), plaque index(PLI), clinical attachment loss(CAL), sulcus bleeding index(SBI)] and levels of periodontal flora [Porphy-romonas gingivalis(Pg), Treponema denticola(Td), Fusobacterium nucleatum(Fn), Prevotella intermedia(Pi)] were compared between the two groups. Results: After 12 weeks of treatment, the total effective rate was 95.56%(43/45) in the laser group, which was significantly higher than 77.78%(35/45) in the control group(χ2=6.154, P=0.013). PD, PLI, CAL and SBI in both groups were significantly lower than those before treatment(all P<0.05), and the improvement in the laser group was significantly better than that in the control group(t=5.656, 4.770, 6.019, 2.386; all P<0.05). Meanwhile, the levels of Pg, Td, Fn and Pi in periodontal tissue of both groups were significantly decreased compared with those before treatment(all P<0.05), and the decreases in the laser group were significantly greater than those in the control group(t=6.499, 8.885, 3.055, 6.062; all P<0.05). Conclusion: Laser combined with routine conservative treatment can significantly improve the clinical efficacy of peri-implantitis, effectively inhibit the prolifera-tion of periodontal pathogenic bacteria, and promote the repair of peri-implant tissues.
参考文献/References:
[1] WANG H L, AVILA-ORTIZ G, MONJE A, et al. AO/AAP con-sensus on prevention and management of peri-implant diseases and conditions: summary report[J]. J Periodontol,2025, 96(6): 519-541.
[2] 郑桂婷,徐燕,吴明月.种植体周围疾病治疗的专家共识及治疗方法的进展[J].国际口腔医学杂志, 2020, 47(6): 725-731.
[3] 黄亭亭,吕宗凯.激光辅助牙周治疗的研究进展[J].四川医学, 2025,46(8):943-947.
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备注/Memo
- 备注/Memo:
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基金项目 国家自然科学基金青年项目(82403921);贵州省基础研究计划(黔科合基础-ZK[2023]一般338);贵州省卫生健康委科学技术基金项目(gzwkj2023-440);贵州医科大学附属口腔医院横向课题(GYKQ2022HX05);贵州医科大学青年科技人才成长项目(22QNRC16)
作者简介 陆雨郡(1999-),女,硕士在读,研究方向:牙周病学;通信作者:李志远,E-mail:lzyuan@gmc.edu.cn。
(2025-08-30收稿)
更新日期/Last Update:
2026-05-25